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Abstract
In the enucleated, arterially perfused cat eye, pilocarpine has been found capable of both increasing and decreasing the rate of aqueous humor formation. Utilizing pharmacologic criteria, the increased formation rate is ascribed to a stimulatory action on E2 sites of sympathetic ganglion-like receptors. The inhibitory response of pilocarpine is attributed to a stimulatory action on E2 sites of similar ganglion-like receptors.