February 1962
Volume 1, Issue 1
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Articles  |   February 1962
The Effect of Ionizing Radiation on Protein and Carbohydrate Metabolism in the rat Lens
Author Affiliations
  • SIDNEY LERMAN
    Department of Surgery, Division of Ophthalmology, University of Rochester School of Medicine and Dentistry.
  • ANIMA DEVI
    Department of Surgery, Division of Ophthalmology, University of Rochester School of Medicine and Dentistry.
  • RENAKA BANERJEE
    Department of Surgery, Division of Ophthalmology, University of Rochester School of Medicine and Dentistry.
Investigative Ophthalmology & Visual Science February 1962, Vol.1, 95-100. doi:
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      SIDNEY LERMAN, ANIMA DEVI, RENAKA BANERJEE; The Effect of Ionizing Radiation on Protein and Carbohydrate Metabolism in the rat Lens. Invest. Ophthalmol. Vis. Sci. 1962;1(1):95-100.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The effects of ionizing radiation on the rat lens were investigated by means of single 1,500 r whole body or head exposures. The results indicate that there is no marked alteration in carbohydrate metabolism within the first week or two after such exposures to x-ray. A marked increase in the incorporation of C-14-leucine only into the insoluble protein-RNA complex of such lenses has been shown to occur within 6 hours after irradiation. A similar increase in the incorporation of P-32 into this albuminoid RNA° also becomes manifest 6 hours after exposure to x-ray.

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