February 1963
Volume 2, Issue 1
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Articles  |   February 1963
Localization of Phosphorylase in the Alloxan-Diabetic Rat Retina
Author Affiliations
  • SHINJI KURIMOTO
    Eye Research Laboratories, The University of Chicago
  • FRANK W. NEWELL
    Eye Research Laboratories, The University of Chicago
Investigative Ophthalmology & Visual Science February 1963, Vol.2, 24-31. doi:https://doi.org/
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      SHINJI KURIMOTO, FRANK W. NEWELL; Localization of Phosphorylase in the Alloxan-Diabetic Rat Retina. Invest. Ophthalmol. Vis. Sci. 1963;2(1):24-31. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Phosphorylase was demonstrated histochemically in the retina of normal and alloxan-diabetic rats. In the normal rat, phosphorylase was present in the inner segments of visual cells, nuclear layers, plexiform layers, ganglion cell layer, and the nerve fiber layer, and. was predominant in the inner layers of the retina. The localization of phosphorylase in the alloxandiabetic rat retina was generally similar to that in the normal rat retina, but the intensity was markedly increased, particularly in the inner layers of the retina. In general, the distribution of phosphorylase corresponded to that of glycogen; however, phosphorylase was present in the absence of detectable glycogen.

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