August 1964
Volume 3, Issue 4
Free
Articles  |   August 1964
Gamma Globulin in Experimental Herpes Simplex Keratitis
Author Affiliations
  • ARMSTEAD B. HUDNELL
    Division of Ophthalmology, Bowman Cray School of Medicine, Wake Forest College, Winston-Salem, N. C., Department of Medicine and Division of Ophthalmology, Duke University School of Medicine, Durham, N. C.
  • SUYDUM OSTERHOUT
    Division of Ophthalmology, Bowman Cray School of Medicine, Wake Forest College, Winston-Salem, N. C., Department of Medicine and Division of Ophthalmology, Duke University School of Medicine, Durham, N. C.
Investigative Ophthalmology & Visual Science August 1964, Vol.3, 366-373. doi:https://doi.org/
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      ARMSTEAD B. HUDNELL, SUYDUM OSTERHOUT; Gamma Globulin in Experimental Herpes Simplex Keratitis. Invest. Ophthalmol. Vis. Sci. 1964;3(4):366-373. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
This content is PDF only. Please click on the PDF icon to access.
Abstract

The chronic keratitis resulting from the steroid treatment of acute herpes simplex infection of the rabbit cornea was significantly improved by the subconjunctival administration of either human or rabbit gamma globulin, the latter possessing no neutralizing antibody to herpes simplex virus. Virus titrations of this late lesion were consistently negative. The etiological and therapeutic implications of these observations will be discussed. It is suggested they provide additional support to the concept that this chronic inflammatory disease is not related to a continuing virus infection.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×