Abstract
The distribution of catechol-O-methyl transferase and monoamine oxidase activity in the ocular tissues of albino rabbits has been determined with a radioactive tracer assay. The distribution of the former varied in the different tissues within a restricted range whereas the distribution of monoamine oxidase activity exhibited larger variations. Sympathetic denervation did not appear to affect catechol-O-methyl transferase levels although moderate decreases in MAO levels were observedone week after denervation. The possible role of these enzymes for catecholamine metabolism in the eye is briefly discussed.