December 1964
Volume 3, Issue 6
Free
Articles  |   December 1964
Chorioretinal Vascular Occlusions with Latex Spheres
Author Affiliations
  • ANDREW J. GAY
    Departments of Ophthalmology and Neurology and the Oscar Johnson Institute, Washington University Medical School, St. Louis, Mo.
  • HOWARD GOLDOR
    Departments of Ophthalmology and Neurology and the Oscar Johnson Institute, Washington University Medical School, St. Louis, Mo.
  • MORTON SMITH
    Departments of Ophthalmology and Neurology and the Oscar Johnson Institute, Washington University Medical School, St. Louis, Mo.
Investigative Ophthalmology & Visual Science December 1964, Vol.3, 647-656. doi:https://doi.org/
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      ANDREW J. GAY, HOWARD GOLDOR, MORTON SMITH; Chorioretinal Vascular Occlusions with Latex Spheres. Invest. Ophthalmol. Vis. Sci. 1964;3(6):647-656. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Latex microspheres of known size have been used to create occlusions in the chorioretinal vasculature of the dog eye. Histologic study of these eyes has shown that capillary occlusion in the nerve fiber layer is sufficient for the production of cytoid body lesions. Occlusion of the choriocapillaris vessels results in overlying retinal ischemia manifested by atrophy and necrosis of the external retinal layers. Large vessel occlusion of the choroid did not lead to retinal changes during the time course of this study.

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