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Arvind Chandna, Philippa M. Pennefather, Ilona Kovács, Anthony M. Norcia; Contour Integration Deficits in Anisometropic Amblyopia. Invest. Ophthalmol. Vis. Sci. 2001;42(3):875-878.
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purpose. Previous retrospective studies have found that integration of orientation
information along contours defined by Gabor patches is abnormal in
strabismic, but not in anisometropic, amblyopia. This study was
conducted to reexamine the question of whether anisometropic amblyopes
have contour integration deficits prospectively in an untreated sample,
to isolate the effects of the disease from the effects of prior
treatment—factors that may have confounded the results in
previous retrospective studies.
methods. Contour detection thresholds, optotype acuity, and stereoacuity were
measured in a group of 19 newly diagnosed anisometropic amblyopes
before initiation of occlusion therapy. Contour detection thresholds
were measured using a card-based procedure.
results. Significant interocular differences in contour detection thresholds
were present in 14 of the 19 patients with anisometropic amblyopia.
conclusions. Contour integration deficits are a common, but not universal, finding
in untreated anisometropic amblyopia. Differences in the prevalence of
contour integration deficits between the present study and that of
another study may lie in differences in treatment history and/or in the
sensitivity of the two different contour integration
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