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Stephen R. Cole, Roy W. Beck, Pamela S. Moke, Robin L. Gal, Danielle T. Long, Optic Neuritis Study Group; The National Eye Institute Visual Function Questionnaire: Experience of the ONTT. Invest. Ophthalmol. Vis. Sci. 2000;41(5):1017-1021.
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purpose. To describe the health-related quality of life, measured with the
National Eye Institute Visual Function Questionnaire (NEI–VFQ), of
patients several years after the onset of optic neuritis, according to
their neurologic and visual status; to assess the relationship between
the NEI–VFQ subscales and clinical measures of visual function; and to
assess the internal consistency reliability of the NEI–VFQ subscales.
methods. The NEI–VFQ was administered to 244 patients 5 to 8 years after
treatment for an episode of acute optic neuritis as part of the Optic
Neuritis Treatment Trial. Visual acuity, visual field, contrast
sensitivity, and color vision were measured at the same time as
results. The NEI–VFQ scores generally were lower than those reported for a
disease-free group. Reported dysfunction was greater when multiple
sclerosis was present and when visual acuity was abnormal, supporting
the construct validity of the NEI–VFQ. Rank correlations between the
NEI–VFQ subscales and clinical measures of visual function were
moderate at best. Internal consistency reliability was generally high
for most of the NEI–VFQ subscales.
conclusions. These findings add support to the use of the NEI–VFQ as a
valuable measure of self-reported visual
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