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John S. Stahl, Mark Lehmkuhle, Kelvin Wu, Benjamin Burke, Dariush Saghafi, Samir Pesh–Imam; Prospects for Treating Acquired Pendular Nystagmus with Servo-Controlled Optics. Invest. Ophthalmol. Vis. Sci. 2000;41(5):1084-1090. doi: https://doi.org/.
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purpose. To determine whether a device featuring electronically controlled
motor-driven prisms can reduce oscillopsia and improve acuity in
patients with acquired pendular nystagmus (APN).
methods. A device was developed that senses eye movements and, by the use of
motor-driven prisms, oscillates the image of the world in lockstep with
the pathologic nystagmus, to negate its deleterious visual effects.
Unlike existing optical and surgical treatments for nystagmus, the
device negates only the pathologic movements. Voluntary and normal
reflex eye movements required for normal vision are unaffected. The
benefits of the device were assessed by its impact on acuity in five
patients with medication-refractory APN.
results. All patients reported decreases in oscillopsia when the device was in
operation. Averaged across patients, the device increased the
percentage of time in which retinal image velocity was within±
4°/sec from 12.8% to 33.3%. Acuities improved in four of five
patients, by an average of 0.21 logMAR units.
conclusions. The symptoms of pendular nystagmus can be treated with a
servomechanical device. Further refinements in the device should result
in greater improvements in acuity, and a portable, wearable version is
feasible using existing technologies.
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