Purchase this article with an account.
Jost B. Jonas, Sohan Singh Hayreh; Ophthalmoscopic Appearance of the Normal Optic Nerve Head in Rhesus Monkeys. Invest. Ophthalmol. Vis. Sci. 2000;41(10):2978-2983.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
purpose. To evaluate the ophthalmoscopic appearance of the normal optic disc,
parapapillary region, and retinal nerve fiber layer in rhesus monkeys.
methods. Color stereo fundus photographs of 17 normal eyes of 17 rhesus monkeys
aged between 13 and 23 years were morphometrically evaluated.
results. The neuroretinal rim was significantly (P < 0.008)
broadest in the inferior disc region followed by the superior disc
region, the nasal region, and the temporal region. Retinal nerve fiber
layer visibility was significantly highest in the inferior temporal
fundus region followed by the superior temporal fundus region, the
superior nasal fundus region, and the inferior nasal fundus region. It
decreased significantly (P < 0.001) with increasing
age. The retinal arterioles were significantly (P <
0.01) wider in the inferior temporal and superior temporal fundus
regions than in the superior nasal and inferior nasal fundus regions.
The alpha zone of parapapillary atrophy (14/17 or 82.4%) occurred
significantly (P < 0.001) more often than the beta
zone (2/17 or 11.8%). In 15 eyes (88.2%), the foveola was located
inferior to a horizontal line drawn through the center of the optic
disc. Neuroretinal rim shape and area and size of alpha and beta zones
of parapapillary atrophy were independent of age.
conclusions. As in humans, in normal rhesus monkeys the neuroretinal rim has a
typical physiologic configuration that spatially correlates with the
retinal arteriole diameter, retinal nerve fiber layer visibility, and
position of the foveola inferior to the center of the optic disc.
Neuroretinal rim shape is independent of age. Retinal nerve fiber layer
visibility decreases significantly with increasing age. These findings
may be useful for the early detection and differentiation of
experimental optic nerve damage in rhesus
This PDF is available to Subscribers Only