Figure 5shows the average intraretinal oxygen distribution before and after delivery of MP laser at a duty cycle of 10% at four different power levels. At a power level of 750 mW (
n = 6) there was no significant difference in the oxygen-consumption rate in the outer retina (
P = 0.782) and no significant increase in retinal oxygen tension in the inner, middle, and outer retina (
P = 0.826, 0.948, and 0.923, respectively). At a power level of 1000 mW (
n = 8) the reduction in oxygen consumption (7.5%) in the outer retina was not statistically significant (
P = 0.358), and the increase in retinal oxygen level in the inner, middle, and outer retina (20.2%, 15.7% and 6.2%, respectively) was not statistically significant (
P = 0.078, 0.103, and 0.175, respectively). At power levels of 1250 (
n = 5) and 1500 (
n = 9) mW, outer retinal oxygen consumption was significantly reduced (57.2%,
P < 0.05 and 86.8%,
P < 0.001). At a power level of 1250 mW, average retinal oxygen levels in the inner, middle, and outer retina were significantly increased (82.5%, 103.6%, and 36.9%; all
P < 0.001). At a power level of 1500 mW (
n = 9), average retinal oxygen levels in the inner, middle, and outer retina were significantly increased (75.3%, 139.6%, and 46.5%; all
P < 0.001). Peak choroidal oxygen level was not affected, even at the 1500-mW level with a 10% duty cycle (
P = 0.121).