OCT3 evaluation of patients with specific macular diseases.
Top left: Idiopathic macular hole: a 6.00-mm long linear OCT scan shows the hyper-reflective operculum (
arrowhead) next to the minimally reflective membrane corresponding to the detached posterior hyaloid. The edges of the hole are thickened by cystic spaces. In the nonaffected macular region, a similar outer retinal tomographic appearance as that in normal eyes is present. However, in the affected area (marked A and B), loss of optical reflectivity (A) and complete disappearance (B) of the inner HRL are shown.
Top right: note that the automatic retinal thickness measurement tool uses the inner HRL at the level of external retina to delineate the outer neural retina border (
outer white line). Manual-caliper–assisted measurement of the distance from the automatic outer generated line to the outer HRL was 66 μm in this case (two aligned crosses in
blue).
Middle left: Central serous chorioretinopathy and no clinical and angiographic evidence of retinal pigment epithelium detachment: 6.00-mm linear scan shows retinal elevation and a discrete increase in retinal thickness (
asterisk) at the macula, due to subretinal fluid accumulation (
dark region) and intraretinal edema. The inner HRL detaches from the outer HRL jointly with the rest of the retina at the edges of the neurosensory retinal detachment.
Middle right: automatic delineation of the neural retina boundaries used the inner HRL to draw the outer limits in less-affected regions and the outer HRL in the area of the neurosensory retinal detachment (
external white line). Note that the manual-caliper–assisted measurement (
blue crosses) of the neural retina was 290 μm when the outer HRL was used to delineate the outer retinal boundary. In the same region, the automated retinal thickness measurement was to 248 μm.
Bottom left: serous retinal pigment epithelial detachment (PED) as confirmed by clinical and angiographic evaluation: 6.00-mm linear scan shows both inner and outer HRL separate from other structures at the nasal edge of the serous PED. Subretinal fluid (above the outer HRL,
) as well as fluid accumulation beneath the outer HRL corresponding to the RPE (
arrows) was seen in the temporal aspect of the OCT scan.
Bottom right: Automatic delineation of the outer neural retina boundary was guided by the inner HRL in the nasal part of the scan (
arrows) and by the outer HRL in the temporal aspect (
arrowheads).