December 1965
Volume 4, Issue 6
Articles  |   December 1965
Metabolism of Catecholamines
Author Affiliations
  • Calvin Hanna
    University of Arkansas Medical Center, Little Rock
Investigative Ophthalmology & Visual Science December 1965, Vol.4, 1095-1102. doi:
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      Calvin Hanna; Metabolism of Catecholamines. Invest. Ophthalmol. Vis. Sci. 1965;4(6):1095-1102.

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      © ARVO (1962-2015); The Authors (2016-present)

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Epinephrine and norepinephrine are derived from tyrosine through the intermediate steps of Dopa and Dopamine. These amines are inactivated in most tissues of the body in several ways through uptake, storage, and metabolism. The catecholamines are found to some extent in the granulated vesicles of cells in the adrenal medtdla and in the neuronal processes of the hypothalamus. Due to a lack of a suitably sensitive method it is difficult to interpret the effect of drugs on the storage sites of the catecholamines


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