October 1965
Volume 4, Issue 5
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Articles  |   October 1965
A Comparative Pharmacologic-histologic Study of Slow and Twitch Fibers in the Superior Rectus Muscle of the Rabbit
Author Affiliations
  • RUDOLF KERN
    Ophthalmology Branch, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Public Health Service, United States Department of Health, Education and Welfare, Bethesda, Md.
Investigative Ophthalmology & Visual Science October 1965, Vol.4, 901-910. doi:
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      RUDOLF KERN; A Comparative Pharmacologic-histologic Study of Slow and Twitch Fibers in the Superior Rectus Muscle of the Rabbit. Invest. Ophthalmol. Vis. Sci. 1965;4(5):901-910.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

The superior rectus muscle of the rabbit can be separated into two plates: One is comprised, solely of Felderstruktur ("slow") fibers and the other almost exclusively of Fibrillenstruktur ("twitch") fibers. Responses of isolated portions of the two muscle types to acetylcholine were compared under identical experimental conditions. The results indicate that the Felderstruktur fibers are responsible for tonic contractions of the extraocular muscles of the rabbit. It is reasonable to assume that they serve the same function in the extraocular muscles of other mammals. Felderstruktur fibers, although striated, demonstrate certain histologic and pharmacologic characteristics, which are intermediate between those of striated and smooth muscle.

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