December 1965
Volume 4, Issue 6
Articles  |   December 1965
The Effects of Oxgyen on Immature Retinal Vessels
Author Affiliations
    Filbert Research Laboratory, Wilmer Institute, Johns Hopkins University, and the Division of Ophthalmology, Department of Surgery, Sinai Hospital, Baltimore, Md.
Investigative Ophthalmology & Visual Science December 1965, Vol.4, 988-999. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      ARNALL PATZ; The Effects of Oxgyen on Immature Retinal Vessels. Invest. Ophthalmol. Vis. Sci. 1965;4(6):988-999.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements
This content is PDF only. Please click on the PDF icon to access.

Nursery observations and animal experimentation have clearly demonstrated a specific toxic effect of oxygen on the immature retinal vessels. In animals having an existing hyaloid structure at birth, oxygen exposure causes an abnormal persistence and apparent proliferation of these vessels. The unique susceptibility of the retinal vessels to oxygen is limited to the retina with an incomplete vasculature; the retina that is fully vascularized is resistant to oxygen damage. Light and electron microscopic observations on the effects of hyperoxia on immature vessels are discussed.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.