homozygosity for novel founder splicing mutation associated with Stargardt-like disease, 4308
macular pigment and lutein supplementation in diseases with, 1319
in severe retinopathies in Spanish patients, 985
Acanthamoeba keratitis, oral immunization for (hamster), 5597
dynamics of accommodative facility in myopes, 4375
infants’ accommodation responses to dynamic stimuli, 949
pharmacologically manipulated accommodative dynamics (monkey), 323
in pre-presbyopes with visual impairment, 3888
spherical aberration changes after lens refilling with silicone oil (pig), 1261
Acetylcholine, muscarinic receptor subtypes on human cornea and conjunctiva, 2987
Acetylcholinesterase, in photoreceptor death after photic stress (rat), 1290
congenital, OCT of macula in, 2249
zebrafish cone photoreceptor–specific promoter and genetic rescue of, 522
Acid/base transporters in lacrimal gland ductal epithelia (rabbit), 3746
Acrolein, protective effect of lipoic acid against toxicity induced in RPE cells by, 339
association of fascin 2 with photoreceptor inner segment actin, 1380
cytoskeletal integrity and MMP-2 activation in TM cells, 2105
Adeno-associated virus (AAV) vectors
AAV-mediated expression targeting of rods and cones with human rhodopsin kinase promoter (mouse), 3954
self-complementary, ocular gene transfer with, 3324
Adenosine and intercellular calcium wave in corneal endothelial cells, 1518
Adenosine triphosphate (ATP), purinergic receptor–mediated regulation of lens connexin43, 4177
adenovirus type 37 keratitis (mouse), 781
topical immunoglobulin treatment of viral ocular infection (rabbit), 4171
Adherence to treatment, pharmacy claims data to study glaucoma medication adherence, 5052
α-2-Adrenergic agonists, effects of topical clonidine vs. brimonidine on choroidal blood flow and IOP during squatting, 4220
α1- and β1-adrenergic modulation of lacrimal gland function in mouse, 1504
α2 adrenergic receptor–mediated modulation of cytosolic Ca++ signals in rat retina, 1410
β-adrenergic receptors in inflammatory marker expression in Müller cells, 5276
Advanced glycation end products, in glaucoma, 1201
Aerosol drug delivery during pars plana vitrectomy, 5243
African-Americans, attitudes about eye examinations, 1989
Age effects. See also Geriatric population; Pediatric population
age, blood pressure, and retinal vessel diameter, 557
age-related decline in parasympathetic nerve fibers in submacular choroid, 479
age-related differences in experimental S. aureus keratitis (rabbit), 5125
calpain 3 and age-related cataracts (mouse), 2685
on connective tissue structure of tree shrew optic nerve, 2134
contrast sensitivity changes in glaucoma and normal aging, 2115
contribution of oculometric parameters to refraction by age and ethnicity, 4846
ferritin H- and L-chains in fiber cell canine and human lenses, 3968
macular temporal responsiveness in normal aging and ARM, 4811
omega 3 fatty acids and IOP with age (rat), 756
restoration of visual responses in aged dystrophic rats after channelopsin-2 gene transfer, 3821
retinal cellular reorganization during normal aging, 2824
on visual spatial integration, 2940
Age-related macular degeneration (AMD)
anxiety and depression in, 1498
basal laminar deposit and membranous debris in early AMD, 968
CFH gene variants, smoking, and AMD risk in Japanese population, 5315
Chlamydia pneumoniae infection and, 4007
circulating hematopoietic stem cells in neovascular AMD, 5464
computer-based test for optimal visual acuity in, 4838
dendritic and synaptic plasticity of neurons in, 2782
estrogen receptor α gene polymorphisms associated with, 1012
genetics of pigment changes and geographic atrophy, 3005
haplotypes spanning complement factor H gene are protective against, 4277
heredity of small hard drusen in twins aged 20–46 years, 833
HPLC measurement of ocular carotenoid levels, 543
Intelligent Distributed Ontology Consensus System, 2278
LOC387715 polymorphism and, 1128
murine Ccl2/Cx3cr1 deficiency results in retinal lesions mimicking, 3827
prevalence of early and late AMD in rural Northern India, 1007
pseudophakia and neovascular AMD, 1472
public health impact of neovascular AMD treatments, 96
reproducibility of quantitative OCT in, 4300
and retinal protein modification by 4-hydroxy-2-nonenal, 3469
scavenger receptors for oxidized lipoprotein in, 1801
SOD2 knockdown mouse model of early AMD, 4407
suppression of choroidal neovascularization by ACE inhibition (mouse), 2321
suprathreshold contrast matching in maculopathy, 3419
synergies of VEGF inhibition and PDT in, 1767
visual loss and visual hallucinations in, 1416
Age-related maculopathy (ARM)
ERG photostress test in evaluation of retinal function in, 2806
Inflammatory markers and hemostatic factors in, 1983
macular temporal responsiveness in normal aging and, 4811
Åland Island eye disease, caused by novel CACNA1F mutation, 2498
inhibition of angiogenesis by intraceptor nanoparticles (mouse), 2030
transcytotic passage through lens epithelial cells, 1237
Aldehyde dehydrogenase class 1A1 (ALDH1A1), postnatal corneal transparency, keratocyte cell cycle exit and expression of (rabbit), 6274061
Aldose reductase, in endotoxin-induced uveitis (rat), 4634
Alkaline phosphatase, in glaucomatous TM, 3184
Alkylphosphocholines, effect on intraretinal proliferation in RD (rabbit), 1305
Alprostadil, effects on ocular hemodynamics, 815
Altitude, high, IOP at, 1622
Alzheimer’s disease, retinal abnormalities in, 2285
anisometropic, spatial contrast sensitivity in, 3622
cortical defects in, 1575
juvenile, perceptual learning and recovery of visual acuity in, 5046
modeling dose-response in children with, 2589
prehension deficits in, 1139
screening and treating, 2084
second-order optic flow deficits in, 5532
strabismic, binocular summation of contrast in, 5332
validation study of VEP Vernier acuity in adults, 4070
endostatin generation by limbal epithelial cells on, 644
fate of limbal epithelial progenitor cells during explant culture on, 605
sutureless transplantation for ocular surface reconstruction, 1528
Amyloid precursor protein (APP) and amyloid-β immunoreactivity in glaucomatous mouse retinas, 5085
Analgesic effects of nepafenac, 182
Anandamide, endocannabinoids in retinal damage after high IOP-induced ischemia in rats, 2997
connective tissue structure of tree shrew optic nerve, 2134
effects of IVF on structural features of neonatal eyes, 5454
horizontal rectus muscle anatomy in strabismic monkeys, 2576
OCT of macular structure in preterm and full-term children, 5207
sonography and MRI of retrobulbar human optic nerve, 1913
3-D atlas of corneal shape, 1072
3-D histomorphometry of early glaucomatous monkey optic nerve head, 5068
3-D histomorphometry of normal and early glaucomatous monkey optic nerve head, 3195, 4597
Angiogenesis. See also Neovascularization
antiangiogenic effect of somatostatin receptor 2 (mouse), 3480
antiangiogenic effects of bisphosphonates (mouse), 5716
bevacizumab inhibition of corneal lymphangiogenesis and (mouse), 2545
15(S)-HETE–induced, role of MEK1 in, 4930
fractalkine mediation of, 5290
inhibition by EMD478761 implant, 5184
inhibition by intraceptor nanoparticles (mouse), 2030
microperimetry in idiopathic macular telangiectasia, 3788
quantitative analysis of choroidal neovascularization, 349
focal macular ERG and angiographic findings after PDT, 2254
topographic, in classic and occult choroidal neovascularization, 1751
Angiotensin-converting enzyme inhibitors, suppression of choroidal neovascularization by (mouse), 2321
Angiotensin II and receptor
angiotensin II type 1 receptor/NF-κB pathway in diabetes-induced retinal inflammation (mouse), 4342
subtypes in human retina, 3301
AAV-mediated expression targeting of rods and cones with human rhodopsin kinase promoter (mouse), 3954
absence of 4–1BB gene function and lacrimal gland inflammation (mouse), 4608
acetylcholinesterase in photoreceptor death after photic stress (rat), 1290
acute superior oblique palsy
change in static eye alignment in (monkey), 2602
changes in dynamic properties during vertical saccades (monkey), 2612
relationship to Listing’s law (monkey), 2621
adenovirus type 37 keratitis (mouse), 781
age-related differences in experimental S. aureus keratitis (rabbit), 5125
aldose reductase in endotoxin-induced uveitis (rat), 4634
α1- and β1-adrenergic modulation of lacrimal gland function in mouse, 1504
α2 adrenergic receptor–mediated modulation of cytosolic Ca++ signals in rat retina, 1410
angiotensin II type 1 receptor/NF-κB pathway in diabetes-induced retinal inflammation (mouse), 4342
antiangiogenic effect of somatostatin receptor 2 (mouse), 3480
antiangiogenic effects of bisphosphonates (mouse), 5716
antiscarring effects of Y-27632 in glaucoma filtration surgery (rabbit), 5549
apolipoprotein A-I and E in developing mouse retina, 1815
APP and amyloid-β immunoreactivity in glaucomatous mouse retinas, 5085
atorvastatin inhibition of choroidal neovascularization (mouse), 1839
axonal transport and cytoskeletal changes with elevated IOP (pig), 3632
bacterial DNA confers neuroprotection after optic nerve injury (mouse and rat), 3441
bacterial transcytosis across conjunctival M cells (guinea pig), 2172
BDNF in retinal protection against light damage–mediated stress (mouse), 2877
bestrophin mutations in canine multifocal retinopathy, 1959
N-cadherin expression in retinal detachment and reattachment (rat), 1832
calcitriol inhibits retinal neovascularization (mouse), 2327
calpain 3 and age-related cataracts (mouse), 2685
capillary degeneration in ischemia/reperfusion injury (rat), 361
carbonic anhydrase inhibitor–induced relaxation of porcine retinal arterioles, 4688
caspase-dependent apoptosis in retinal degeneration (rat), 2753
CCR1 deletion prolongs corneal allograft survival (mouse), 1228
CD18 integrins and neutrophil–keratocyte interactions during corneal wound healing (mouse), 5023
cellular response to photoreceptor death in murine RD, 849
ceruloplasmin upregulation in glaucoma (mouse), 727
changes in pericytes and smooth muscle cells in ROP (kitten), 1368
characteristics of progenitor cells from ciliary body in mouse, rat, and human eyes, 1674
chemokine profile and autoimmune pathology in genetic IFN-γ deficiency (mouse), 4616
chondroitin sulfate-derived disaccharide protects retinal cells from elevated IOP (rat), 1181
choroidal regulation of scleral glycosaminoglycan synthesis during recovery from induced myopia (chick), 2957
clearance of intravitreal voriconazole (rabbit), 2238
CNTF-induced cellular changes in murine RP, 1389
CNTF reduces vision in rats in dose-dependent manner, 5756
complement factor D and photoreceptor susceptibility to light-induced damage (mouse), 5282
cone loss with impaired choroidal circulation after light exposure (rat), 1864
connective tissue structure of tree shrew optic nerve, 2134
connexins and lens epithelial cell proliferation (mouse), 5630
controlling RPE injury after experimental retinal detachment (mouse), 1348
corneal epithelial changes in diabetic Goto-Kakizaki rat, 590
corneal virulence of Candida albicans strains deficient in Tup1-regulated genes (mouse), 2535
cross-axis eye movements in primates with A pattern strabismus, 665
γD-crystallin–associated protein aggregation and lens fiber cell denucleation (mouse), 3719
cultivated corneal endothelial cell sheet transplantation (monkey), 4519
CX3CR1 mediates homing of MHC class II–positive cells to mouse corneal epithelium, 1568
cyclic ADP-ribose–dependent calcium signaling pathway in bovine rod outer segments, 978
dacryoadenitis in IL-4 deficient MRL/MpJ mice, 5624
density and distribution of neuromuscular junctions in normal and botulinum toxin–treated EOMs (rabbit and monkey), 3594
differential sensitivity of cones to iron-mediated oxidative damage (mouse), 438
differentiation of retinal stem cells transplanted into murine RP models, 446
DNase IIβ in mouse lens, 5638
downregulation of endotoxin-induced uveitis by intravitreal VIP encapsulated in liposomes (rat), 3230
effect of 15-keto latanoprost on IOP and aqueous humor dynamics (monkey), 4143
effect of alkylphosphocholines on intraretinal proliferation in RD (rabbit), 1305
effect of ocular hypertension on retinal nitridergic pathway activity (rat), 2127
effect of spectral characteristics of Ganzfeld stimuli on photopic negative response of ERG (monkey), 4818
effect of transcorneal electrical stimulation in acute-phase optic nerve injury (rat), 2356
effects of foveal ablation on emmetropization and form-deprivation myopia (monkey), 3914
effects of intravitreous bevacizumab on neovascularization (rabbit), 5708
effects of topical Y-39983 on ocular tissues in rabbits and monkeys, 3216
endocannabinoids in retinal damage after high IOP-induced ischemia in rats, 2997
endogenous TNFα suppression of neovascularization in corneal stroma (mouse), 3051
endoplasmic reticulum stress activation in degenerating photoreceptors (mouse), 5191
EPA prevents choroidal neovascularization in mice, 4328
EphB2 and ephrin-B2 upregulation at optic nerve head in glaucomatous mice with axon loss, 5567
evaluation of novel dry eye model (rabbit), 4468
evaluation of retinal status using chromatic pupil light reflex activity (dog), 5178
expression of Th-1 chemokines and receptors in mouse model of dry eye, 2561
expression profiling of retinoschisin-deficient retina in postnatal mouse development, 891
fascicular specialization in human and monkey rectus muscles, 3089
ferritin H- and L-chains in fiber cell canine and human lenses, 3968
flash-induced light reflectance changes in macaque retina, 2903
form-deprivation myopia in chick and retinal gene expression, 3430
function of visual arrestins in rod photoreceptors (mouse), 1968
functional assessment of subretinal prosthetic (rat), 916
gas jets in pneumatic retinopexy (pig), 2734
GDNF stimulation of rods and dopaminergic amacrine cells (chick), 5306
gene expression analysis of photoreceptor cell loss in Bbs4-knockout mice, 3329
gene expression in experimental glaucoma and optic nerve transection (rat), 5539
gene expression profiling of zebrafish embryonic RPE, 881
genetic ablation of cone photoreceptors and retinal fold elimination in rd7 mouse, 2799
genetic determinant of retinal degeneration on mouse chromosome 6, 405
genetics and susceptibility to oxygen-induced retinopathy (rat), 1761
glial contributions to retinal detachment–induced photoreceptor degeneration (mouse), 2760
glycosaminoglycan levels in tree shrew sclera during induced myopia development and recovery, 2947
GNPTAB deficiency (mouse), 5221
HDL transport of lutein into retina (chick), 4226
high-resolution manganese-enhanced MRI of experimental ROP (rat), 4733
histogenesis of intravitreal membrane and secondary vitreous (mouse), 1923
horizontal rectus muscle anatomy in strabismic monkeys, 2576
horizontal saccade disconjugacy in strabismic monkeys, 3107
Hsp27 phosphorylation in experimental glaucoma (rat), 4129
HSV-1–dependent apoptosis in corneal epithelial cells (rabbit), 4980
hyperoxia and oxygen consumption in detached feline retina, 1335
IFN-γ modulation of dry eye–induced conjunctival epithelial squamous metaplasia (mouse), 2553
IL-17+ interphotoreceptor retinoid-binding protein-specific T cells in EAU (mouse), 4153
impaired apparent ion demand in experimental diabetic retinopathy (rat), 4753
inducible NOS in diabetic retinopathy (mouse), 5257
influence of thyroid hormone on lacrimal gland and ocular surface morphology (rat), 3038
inhibition of angiogenesis by intraceptor nanoparticles (mouse), 2030
inhibition of diabetic leukostasis and blood–retinal barrier breakdown (mouse), 858
innervation of tissue-engineered corneal implants (pig), 3537
iNOS and CMV spread in retina (mouse), 285
interaction between Tubby-like protein 1 and dynamin-1 (mouse), 2837
intramembrane determinant of peripherin/rds function for photoreceptor disk morphogenesis (mouse), 2975
IOP-dependent RCG dysfunction in glaucomatous DBA/2J mice, 4573
keratan sulfate in developing avian cornea, 3083
laminins essential for basement membrane integrity (zebrafish), 2483
late-onset cone degeneration induced by Rds mutation and gene rescue (mouse), 5397
layer-specific differences in rat EOM M-bands, 1119
light exposure, photoreceptor degeneration, and AP-1 activation (dog), 4907
light-scattering and ultrastructure of healed penetrating corneal wounds (rabbit), 157
linkage mapping of ovine microphthalmia to chromosome 23, 3506
loss of insulin-mediated vasoprotection (rat), 2350
LYVE-1–positive macrophages in murine eyes, 2162
macrophages as determinants of ocular HSV-1 infection in immunized mice, 5605
manganese-enhanced MRI of choroidal melanoma xenografts (rat), 963
manganese-enhanced MRI studies of intraretinal ion demand in ocular injury (rat), 3796
manipulation of MMPs to reduce retinal neovascularization in oxygen-induced retinopathy (rat), 907
mechanism of retinoblastoma tumor cell death after chemotherapy, radiation, and vascular targeting therapy (mouse), 5371
melanopsin-dependent persistence and photopotentiation of pupillary responses (mouse), 1268
memantine effects in diabetic retinopathy (rat), 5152
microRNAs expressed in mouse eye, 509
miRNA expression in human and rat retinas, 3962
mitochondrial oxidative damage and diabetic retinopathy (mouse), 3805
modeling behavior of uveal melanoma in mouse liver, 2967
murine Ccl2/Cx3cr1 deficiency results in retinal lesions mimicking human AMD, 3827
mutant ND4-induced optic neuropathy (mouse), 1
neural reprogramming in retinal degeneration (mouse), 3364
neuroprotection in juvenile rat model of light-induced retinopathy, 2311
neuroprotective effect of erythropoietin on RGCs in glaucoma mice, 1212
neurotrophic factors minimize renal toxicity of verteporfin PDT (rat), 430
neurotrophins in rat conjunctival goblet cells, 1543
new mouse model of autoimmune ocular myasthenia gravis, 5101
new tools for evaluation of toxic ocular surface changes in rat, 5473
NGF gene therapy improves corneal allograft survival (rat), 1043
nondestructive quantification of analyte diffusion using OCT (rabbit), 2726
nonproteolytically activated prorenin in retinal neovascularization (mouse), 422
novel alternatively spliced isoforms of RTEF-1 in endothelial cells and murine retina, 3775
novel dendritic cell populations in mouse retina, 1701
novel form of transducin-dependent RD (mouse), 5445
OCT and histology of RNFL thickness in glaucoma (monkey), 3645
ocular hypopigmentation in Rab38cht/cht mice, 3905
OFF-type blue cone bipolar cell in rabbit retina, 3388
omega 3 fatty acids and IOP with age (rat), 756
opsin expression during retinal development in salmonid fishes, 866
optic nerve head gene expression after exposure to elevated IOP in rat glaucoma model, 3161
optical imaging of retina activated by suprachoroidal-transretinal stimulation (cat), 4777
optical zone decentration and aberrations after PRK (cat), 5806
optomechanical response of human and monkey lenses in a lens stretcher, 3260
oral immunization for Acanthamoeba keratitis (hamster), 5597
oscillatory potentials of dark-adapted ERG in ROP (rat), 5788
oxidative stress and blink-suppressed dry eye (rat), 1552
panretinal, high-resolution color photography of mouse fundus, 2769
pathological and electrophysiological features of canine cone–rod dystrophy, 4240
pattern ERG monitoring of RGC dysfunction in murine glaucoma, 745
Pax6 expression in pigeon retina, 2503
Pax6 required for postnatal eye development (mouse), 3292
PDT and apoptosis in rat choroidal neovascularization model, 4741
persistent hyperplastic primary vitreous due to somatic mosaic deletion of Arf (mouse), 491
pharmacologically manipulated accommodative dynamics (monkey), 323
photoreceptor protection against light damage by heme oxygenase-1 overexpression (rat), 5699
polylactic acid for visualizing vitreous body during vitrectomy (rabbit), 3277
posterior pole injury and peripheral RPE proliferation (pig), 355
postnatal corneal transparency, keratocyte cell cycle exit and expression of ALDH1A1 (rabbit), 6274061
preclinical safety evaluation of intravitreal VEGF antibody injection (rabbit), 1773
progressive RGC dysfunction in DBA/2J mouse model of glaucoma, 4564
prostaglandin FP receptors and 24-hour IOP variation in mice, 2095
protective effect of basic FGF-impregnated nanoparticles in RCS rats, 3381
protective effect of TEMPOL derivatives against light-induced retinal damage (rat), 1900
protective effects of uridine on cornea in rabbit dry eye model, 1102
proteolytic mechanisms underlying mitochondrial degradation in lens (mouse), 293
Pseudomonas keratitis in cathelicidin-deficient mice, 4498
quail retinal carotenoids, 3976
rapid recruitment of TIP47 in RPE (mouse), 2858
real-time IOP during LASIK with mechanical microkeratome and femtosecond laser (pig), 68
reduced photoreceptor damage after PDT through NOS blockade (monkey), 2268
refractive defects and cataracts in Lim2 null mice, 500
regional differences in cystine accumulation in rat lens, 1253
regulation of acid/base transporters in lacrimal gland ductal epithelia (rabbit), 3746
regulatory T cells enhance retinal graft survival (mouse), 5112
relationship between RNFL and perimetry measurements (monkey), 763
relative axial myopia in Egr-1 knockout mice, 11
restoration of visual responses in aged dystrophic rats after channelopsin-2 gene transfer, 3821
resveratrol-induced dilation of porcine retinal arterioles, 4232
Ret activation does not protect from light-induced damage (mouse), 5199
retinal alterations in zebrafish laminin mutants, 2887
retinal oxygen metabolism in retinal artery occlusion (rat), 2290
retinal penetration of bevacizumab after intravitreal injection (monkey), 2814
retinal toxicity of intravitreal triamcinolone acetonide (rabbit), 390
retinoblastoma tumor vessel maturation (mouse), 2476
retinoschisin gene therapy in Rs1h-KO mouse, 3837
retinoschisin in murine retina, 991
rod function predicts blood vessel abnormality in ROP (rat), 4351
role of apoptosis in resolution of experimental autoimmune anterior uveitis (rat), 5091
role of GLYT2 in glycine uptake in lens core (rat), 5142
role of macrophage migration inhibitory factor in neovascularization (mouse), 3545
role of ST2 in Pseudomonas keratitis (mouse), 4626
RPE65 essential for cone function in NRL-deficient mice, 534
Schwann cell transplantation preserves vision without immunosuppression (rat), 1906
selective RPE targeting with laser scanner (rabbit), 1782
sensitivity to light-induced damage in autosomal dominant retinal disease (mouse), 1942 (erratum, 3436)
simultaneous defocus integration during refractive development (chick), 5352
simultaneous fundus imaging and OCT in mouse retina, 1283
simvastatin-induced dilation of porcine retinal arterioles, 825
slow-releasing tranilast in PTFE/PLGA after strabismus surgery (rabbit), 699
SOD2 knockdown mouse model of early AMD, 4407
somatic ablation of Lrat gene in mouse RPE, 5377
spantide I in Pseudomonas aeruginosa keratitis (mouse), 797
spectral-domain OCT for 3D retinal imaging of rodent retina, 1808
spherical aberration changes after lens refilling with silicone oil (pig), 1261
Src suppression blocks posterior capsule opacification (chick), 2214
structural specializations emerging late in mouse lens fiber cell differentiation, 3269
suppression of choroidal neovascularization by ACE inhibition (mouse), 2321
suppression of choroidal neovascularization by dendritic cell vaccination targeting VEGFR2 (mouse), 4795
suppression of experimental autoimmune uveitis by anti-LFA-1α Ab (mouse), 2667
suppression of mitochondrial oxidative stress in optic neuritis (mouse), 681
susceptibility of eyes of lower vertebrate to visual environment (tilapia), 4829
synaptic contact between melanopsin-containing RGCs and rod bipolar cells (rat), 3812
temporal constraints on experimental emmetropization in infant monkeys, 957
Th1/Th2 cytokine profile in primary intraocular B-cell lymphoma (mouse), 3223
3-D histomorphometry of early glaucomatous monkey optic nerve head, 5068
3-D histomorphometry of normal and early glaucomatous monkey optic nerve head, 3195, 4597
TNF-α–induced apoptosis in murine CMV retinitis, 1691
tolerance to retinal ischemia by hypoxic preconditioning (mouse), 1735
topical immunoglobulin treatment of adenoviral ocular infection (rabbit), 4171
topotecan vitreous levels after periocular or intravenous delivery for retinoblastoma (rabbit), 3761
transcorneal electrical stimulation protection of photoreceptors (rat), 4725
transgenic analysis of rodent anterior ischemic optic neuropathy–induced RGC stress and loss (mouse), 2304
transgenic corneal neurofluorescence in mice, 1535
transplantable rabbit carrier-free epithelial sheets, 597
truncated rhodopsin in rod function and degeneration (moue), 2868
upregulation of VEGF after retinal scatter laser photocoagulation (mouse), 5677
valsartan amelioration of retinal dysfunction in diabetic rats, 927
VEGF in retinal progenitor cell proliferation in murine retinal degeneration, 4315
visual system vulnerability to prenatal endotoxin exposure (sheep), 472
wound healing after corneal femtosecond laser keratotomy (rabbit), 2068
zebrafish cone photoreceptor–specific promoter and genetic rescue of achromatopsia, 522
Aniseikonia, validity and repeatability of new test for, 58
Anisometropic amblyopia, spatial contrast sensitivity in, 3622
Anterior capsular plaque in congenital cataract, 4209
dynamic analysis of dark–light changes with anterior segment OCT, 4116
measurements by OCT, 3683
Anti-leukocyte function associated antigen (LFA)-1α Ab, suppression of experimental autoimmune uveitis by (mouse), 2667
Antifungal therapy, clearance of intravitreal voriconazole (rabbit), 2238
Antigen-presenting cells in fresh and cultured human corneas, 4459
Anti–glycoproteins D and K IgGs in herpes stromal keratitis, 2185
bimatoprost, prostamide activity, and conventional drainage, 4107
effect of 15-keto latanoprost on IOP and aqueous humor dynamics (monkey), 4143
effects of topical clonidine vs. brimonidine on choroidal blood flow and IOP during squatting, 4220
effects of topical Y-39983 on ocular tissues in rabbits and monkeys, 3216
in vitro studies of antiglaucomatous prostaglandin analogues, 4123
mass treatment of trachoma and ocular Chlamydia trachomatis, 1492
phase 3 safety comparisons for 1.0% azithromycin in polymeric mucoadhesive eye drops vs. 0.3% tobramycin eye drops for bacterial conjunctivitis, 3425
photoreceptor protective effect of minocycline, 412
gene therapy in optic neuritis (mouse), 5360
lutein and zeaxanthin protect photoreceptors from oxidative stress–induced apoptosis, 5168
Antiproliferative drugs, modulation of cholesterol homeostasis in pterygium fibroblasts, 3450
Anxiety and depression in AMD, 1498
AP-1 activation, light exposure, photoreceptor degeneration and (dog), 4907
APITD1 expression and uveal melanoma, 4919
Apolipoprotein A-I and E in developing mouse retina, 1815
acetylcholinesterase in photoreceptor death after photic stress (rat), 1290
antiapoptotic effects of thymosin β-4 on corneal epithelial cells, 27
apoptotic response of HSV-1 in corneal epithelial cells, 789 (erratum, 1000)
Bcl-xL in survival of RPE cells, 3846
bortezomib-induced apoptosis in human retinoblastoma cell lines, 4706
calpains in RGC death, 5420
CaMKIIαB mediates survival response in RGCs, 3854
caspase-8–mediated apoptosis in RPE cells, 3341
caspase-dependent, in retinal degeneration (rat), 2753
cellular response to photoreceptor death in murine RD, 849
cytotoxicity evaluation of different vegetable oil vectors, 5000
HSV-1–dependent apoptosis in corneal epithelial cells (rabbit), 4980
IFN-α and IFN-γ sensitize Tenon fibroblasts to mitomycin-C, 3655
light exposure, photoreceptor degeneration, and AP-1 activation (dog), 4907
lutein and zeaxanthin protect photoreceptors from oxidative stress–induced apoptosis, 5168
mechanism of retinoblastoma tumor cell death after chemotherapy, radiation, and vascular targeting therapy (mouse), 5371
NF-κB and MAPKs in photoreceptor apoptosis, 4766
optineurin mutant induces death of RGCs, 1607
p53 expression and lens apoptosis after UV radiation exposure (rat), 4187
PDT and apoptosis in rat choroidal neovascularization model, 4741
plasminogen activators cause death of RGCs, 1884
protective effect of caffeine against UV-induced apoptosis in corneal epithelial cells, 652
role in resolution of experimental autoimmune anterior uveitis (rat), 5091
sodium 4-phenylbutyrate corrects myocilin misfolding and rescues cells from, 1683
TNF-α–induced apoptosis in murine CMV retinitis, 1691
Aquaporin-1–independent microvessel proliferation in murine oxygen-induced retinopathy, 4802
bimatoprost, prostamide activity, and conventional drainage, 4107
effect of 15-keto latanoprost on IOP and aqueous humor dynamics (monkey), 4143
Arf gene, persistent hyperplastic primary vitreous due to somatic mosaic deletion of (mouse), 491
Arrestins, function in rod photoreceptors (mouse), 1968
CFH gene variants, smoking, and AMD risk in Japanese population, 5315
gene mutations in Japanese patients with Norrie disease and familial exudative vitreoretinopathy, 1276
Heidelberg Retina Tomograph of optic disc and RNFL in Singapore children, 4939
IL-1 gene cluster polymorphisms and glaucoma in Chinese subjects, 2123
imaging comparison of optic disc and RNFL in glaucoma detection, 2644
Liwan Eye Study, slit lamp–simulated oblique flashlight test in Chinese eyes, 5459
ocular dominance, laterality, and refraction in Singaporean children, 3533
Shihpai Eye Study, correctable visual impairment in elderly Taiwanese, 1032
208delG mutation in FSCN2 in Chinese individuals, 530
visual acuity measurement in Chinese reading population, 2383
D-β-Aspartic acid–containing proteins, localization in human eyes, 3923
Aspartyl proteinases in Candida albicans keratitis (mouse), 3559
Astigmatism, in 12-year-old Australian children, 73
Endothelin-1–mediated signaling in expression of MMPs and TIMPs in, 3737
population differences in elastin maturation in optic nerve head and, 3209
Atorvastatin, inhibition of choroidal neovascularization by (mouse), 1839
Atropine, pharmacologically manipulated accommodative dynamics (monkey), 323
Axenfeld-Rieger syndrome, genotype-phenotype correlations in Axenfeld-Rieger malformation and glaucoma with FOXC1 and PITX2 mutations, 228
Azithromycin, phase 3 safety comparisons for 1.0% azithromycin in polymeric mucoadhesive eye drops vs. 0.3% tobramycin eye drops for bacterial conjunctivitis, 3425
c-Met and EGFR in RPE wound healing, 2242
CACNA1F gene, novel mutation causes Åland Island eye disease, 2498
N-cadherin expression in retinal detachment and reattachment (rat), 1832
TGF-β1 repression of E-cadherin via Slug expression in lens epithelium, 2708
Caffeine, protective effect against UV-induced apoptosis in corneal epithelial cells, 652
Calcitriol, inhibition of retinal neovascularization by (mouse), 2327
adenosine and intercellular calcium wave in corneal endothelial cells, 1518
α2 adrenergic receptor–mediated modulation of cytosolic Ca++ signals in rat retina, 1410
cyclic ADP-ribose–dependent calcium signaling pathway in bovine rod outer segments, 978
thrombin inhibition of intercellular Ca2+ wave propagation in corneal endothelial cells, 120
TRPC channels mediate basal calcium entry in RPE cells, 5767
calpain 3 and age-related cataracts (mouse), 2685
CaMKIIαB mediates survival response in RGCs, 3854
corneal virulence of Candida albicans strains deficient in Tup1-regulated genes (mouse), 2535
secreted aspartyl proteinases in Candida albicans keratitis (mouse), 3559
virulence in keratomycosis (mouse), 774
Canine multifocal retinopathy, bestrophin mutations in, 1959
Cannabinoid receptors and bimatoprost-induced contractions of ciliary muscle, 3677
Capillary degeneration in ischemia/reperfusion injury (rat), 361
Carbonic anhydrase inhibitor–induced relaxation of porcine retinal arterioles, 4688
Carbonic anhydrase IV gene mutation and RP, 3459
Carboxymethylcellulose, in corneal epithelial wound healing, 1559
dietary, macular pigment optical density and, 571
HPLC measurement of ocular levels of, 543
identification of 3-methoxyzeaxanthin in macula, 1435
activation by 7-ketocholesterol in retinal neurosensory cells, 1362
caspase-8–mediated apoptosis in RPE cells, 3341
caspase-dependent apoptosis in retinal degeneration (rat), 2753
PDT and apoptosis in rat choroidal neovascularization model, 4741
atopic, interferon gamma receptor 1 polymorphisms and, 583
biometry of Caucasian and African-American cataractous pediatric eyes, 4671
calpain 3 and age-related cataracts (mouse), 2685
anterior capsular plaque in, 4209
homozygous CRYBB1 deletion in, 2208
γD-crystallin–associated protein aggregation and lens fiber cell denucleation (mouse), 3719
degradation of C-terminal αA-crystallins in, 4200
genetic heterogeneity in microcornea-cataract, 3937
INDEYE Feasibility Study, prevalence of lens opacities in North India, 88
in vitro generation of functional lens-like structures, 1245
lens epithelial cell response to quercetin and DMSO, 3714
light scattering predicted from particles in nuclear cataracts using Mie scattering theory, 303
and refractive defects in Lim2 null mice, 500
retinoic acids and cataractogenesis, 2224
visual adaptation to interocular brightness differences, 935
lens cell survival in stressed capsular bag, 2701
pseudophakia and neovascular AMD, 1472
Src suppression blocks posterior capsule opacification (chick), 2214
β-Catenin, and epithelial–mesenchymal transition in pathogenesis of pterygium, 1511
Cathelicidin-deficient mice, Pseudomonas keratitis in, 4498
Cathepsin, endostatin generation by MMP and cathepsin from limbal epithelial cells on amniotic membrane, 644
Ccl2/Cx3cr1 deficiency in mouse results in retinal lesions mimicking human AMD, 3827
CCR1, deletion prolongs corneal allograft survival (mouse), 1228
in experimental autoimmune uveitis (mouse), 2178
modulation of CD8+ cytotoxic T lymphocyte effector function by fibroblasts derived from immunoprivileged cornea (mouse), 2194
CD18 integrins and neutrophil–keratocyte interactions during corneal wound healing (mouse), 5023
CD44, lactate causes NF-κB activation and CD44 shedding in cultured TM cells, 1615
Cell cycle, Pax6 p46 overexpression induces mitosis defect, 5408
Cell death. See Apoptosis and cell death
Cell junction–related proteins, in gelatinous drop-like corneal dystrophy, 1095
Central retinal venous occlusion, hyperhomocysteinemia and low methionine stress as risk factors for, 1441
CERKL mutation, in autosomal recessive RD among Yemenite Jews, 5431
Ceruloplasmin, upregulation in glaucoma (mouse), 727
Channelopsin-2 gene transfer, restoration of visual responses in aged dystrophic rats after, 3821
Charles Bonnet syndrome, 1416
CCR1 deletion prolongs corneal allograft survival (mouse), 1228
chemokine profile and autoimmune pathology in genetic IFN-γ deficiency (mouse), 4616
CX3CR1 mediates homing of MHC class II–positive cells to mouse corneal epithelium, 1568
CXCR3 effects in HSV-infected mice, 4162
expression of Th-1 chemokines and receptors in mouse model of dry eye, 2561
fractalkine mediation of ocular angiogenesis, 5290
mitomycin C upregulates chemokine expression in corneal fibroblasts, 2009
multiplex bead analysis of vitreous humor, 2203
murine Ccl2/Cx3cr1 deficiency results in retinal lesions mimicking human AMD, 3827
Chemotherapy, for retinoblastoma
antitumor action of neurokinin-1 receptor antagonist, 2775
mechanism of tumor cell death after chemotherapy, radiation, and vascular targeting therapy (mouse), 5371
paclitaxel treatment in murine model, 3437
topotecan vitreous levels after periocular or intravenous delivery (rabbit), 3761
Children. See Pediatric population
IL-1 gene cluster polymorphisms and glaucoma in, 2123
Liwan Eye Study, slit lamp–simulated oblique flashlight test in Chinese eyes, 5459
Shihpai Eye Study, correctable visual impairment in elderly Taiwanese, 1032
visual acuity measurement in reading population, 2383
Chlamydia pneumoniae infection and AMD, 4007
Chlamydia trachomatis, ocular
bacterial infection and trachoma in The Gambia, 4440
mass treatment of trachoma and, 1492
Chloride channel activity of bestrophin mutants causing macular degeneration, 4694
HDL transport of lutein into retina (chick), 4226
modulation of cholesterol homeostasis by antiproliferative drugs in pterygium fibroblasts, 3450
as treatment for pneumococcal keratitis (rabbit), 2661
Cholinergic agonists and endotoxin-induced uveitis (rat), 2719
Chondroitin sulfate-derived disaccharide protects retinal cells from elevated IOP (rat), 1181
characteristics of progenitor cells from (mouse, rat, and human), 1674
retinal phenotypes in mammalian ciliary body after RGC injury (mouse), 5266
Ciliary epithelium, fluid transport across, 321
Ciliary muscle, cannabinoid receptors and bimatoprost-induced contractions of, 3677
Ciliary neurotrophic factor (CNTF)
cellular changes in murine RP induced by, 1389
chemotactic effect on macrophages in RGC survival and axonal regeneration (rat), 4257
neuroprotection in juvenile rat model of light-induced retinopathy, 2311
reduction of vision in rats in dose-dependent manner, 5756
control of tyrosine phosphorylation of cGMP-gated ion channels in chick photoreceptors, 901
fluctuation of mean ocular perfusion pressure as risk factor for normal-tension glaucoma, 104
cost-effectiveness of cycloplegic agents in Nigerian children, 1025
effects of pentoxifylline and alprostadil on ocular hemodynamics, 815
phase 3 safety comparisons for 1.0% azithromycin in polymeric mucoadhesive eye drops vs. 0.3% tobramycin eye drops for bacterial conjunctivitis, 3425
Clonidine, topical, vs. brimonidine on choroidal blood flow and IOP during squatting, 4220
CNGB3 achromatopsia, 3864
Coated microneedles for drug delivery, 4038
cellular and functional OCT of human retina, 5340
Wolfgang Drexler, 2007 recipient of Cogan Award, 5339
Cognitive ability and retinal vascular network geometry in elderly population, 1995
collagen cross-linking and IOP measurement, 5494
composition of infant vs. adult human corneal basement membranes, 4989
loss of α3(IV) collagen in activated corneal keratocytes, 627
regulation of corneal fibroblasts by ECM mechanical properties, 5030
second-harmonic imaging microscopy of corneas, 1087
brightness sensitivity and color perception as predictors of relative afferent pupillary defect, 3616
CNGB3 achromatopsia, 3864
gender and color vision defects in asymptomatic carriers of Leber’s hereditary optic neuropathy, 2362
OCT of macula in congenital achromatopsia, 2249
zebrafish cone photoreceptor–specific promoter and genetic rescue of achromatopsia, 522
Complement factor D, and photoreceptor susceptibility to light-induced damage (mouse), 5282
CFH gene variants, smoking, and AMD risk in Japanese population, 5315
haplotype protection in AMD, 4277
inflammatory mediators, retinal vessel diameters and polymorphism of, 3014
computer-based test for optimal visual acuity in AMD, 4838
electronic medical records system for clinical research and the EMR–EDC interface (new developments), 4383
ABCA4 mutations in severe retinopathies in Spanish patients, 985
in vivo imaging of RPE mosaic in diseased retina, 2297
macular pigment and lutein supplementation in ABCA4 disease, 1319
Cones. See Photoreceptors
bacterial transcytosis across conjunctival M cells (guinea pig), 2172
corneal innervation and sensitivity in patients with dry eye, 173
CX3CR1 mediates homing of MHC class II–positive cells to mouse corneal epithelium, 1568
in vivo confocal study of cornea in Sjögren’s syndrome, 2017
innervation of tissue-engineered corneal implants (pig), 3537
ocular dominance, laterality, and refraction in Singaporean children, 3533
Confocal scanning laser ophthalmoscopy
diagnostic accuracy in glaucoma, 214
optic disc measurements in myopia with OCT and, 3178
repeatability in glaucoma, 1156
allergic conjunctival inflammation and allogeneic response to donor cornea, 4044
bacterial transcytosis across M cells of (guinea pig), 2172
bone marrow–derived cells in substantia propria of, 4476
comparison of gene expression in human cornea and, 2050
expression of Th-1 chemokines and receptors in mouse model of dry eye, 2561
IFN-γ modulation of dry eye–induced conjunctival epithelial squamous metaplasia (mouse), 2553
muscarinic receptor subtypes on human cornea and, 2987
neurotrophins in rat conjunctival goblet cells, 1543
phase 3 safety comparisons for 1.0% azithromycin in polymeric mucoadhesive eye drops vs. 0.3% tobramycin eye drops for bacterial conjunctivitis, 3425
regulation of IL-8 by S. aureus in conjunctival cells, 270
lens epithelial cell proliferation and (mouse), 5630
purinergic receptor–mediated regulation of lens connexin43, 4177
Contact lens, measurement of corneal swelling without removal of, 3043
binocular summation of contrast in strabismic amblyopia, 5332
changes in glaucoma and normal aging, 2115
in children with infantile spasms, 3610
effect of myopia on contrast thresholds, 2371
and higher-order aberrations after orthokeratology, 550
measured with transient VEP, 3396
spatial, in anisometropic amblyopia, 3622
Convergence, variation of binocular–vertical fusion amplitude with, 1592
activation of prothrombin to form thrombin, 134
adenovirus type 37 keratitis (mouse), 781
analgesic effects of nepafenac, 182
biomechanical properties of cornea, 3026
Candida virulence in keratomycosis (mouse), 774
characterization of antigen-presenting cells in fresh and cultured human corneas, 4459
comparison of gene expression in human conjunctiva and, 2050
corneal elasticity in damping of IOP, 2540
corneal virulence of Candida albicans strains deficient in Tup1-regulated genes (mouse), 2535
endogenous TNFα suppression of neovascularization in corneal stroma (mouse), 3051
expression of IDO in human corneal cells, 4148
functional optical zone of, 1053
genetic heterogeneity in microcornea-cataract, 3937
impulse activity in corneal sensory nerve fibers after PRK, 4032
influence of eyelid morphology on corneal shape, 112
innervation and sensitivity in patients with dry eye, 173
loss of α3(IV) collagen in activated keratocytes, 627
measurement of corneal swelling without removal of contact lens, 3043
mitomycin C upregulates chemokine expression in corneal fibroblasts, 2009
muscarinic receptor subtypes on human conjunctiva and, 2987
objective measurement of backscattered light from, 167
pachymetric mapping with Visante anterior segment-OCT, 5499
protective effects of uridine in rabbit dry eye model, 1102
second-harmonic imaging microscopy of, 1087
3-D atlas of corneal shape, 1072
TLR-3 and -9 in human corneal myofibroblasts, 3069
transgenic corneal neurofluorescence in mice, 1535
UBIAD1 mutations in Schnyder crystalline corneal dystrophy, 5007
Corneal endothelial cells
adenosine and intercellular calcium wave in, 1518
cultivated corneal endothelial cell sheet transplantation (monkey), 4519
cultured, cryopreservation and genetic modification of, 3056
isolation, preservation, and expansion of, 614
reproducibility of endothelial assessment, 2062
thrombin inhibition of intercellular Ca2+ wave propagation in, 120
two semiautomated methods for evaluating endothelial cells of eye bank corneas, 3077
antiapoptotic effects of thymosin β-4 on, 27
apoptotic response of HSV-1 in, 789 (erratum, 1000)
benzalkonium chloride–induced dephosphorylation of myosin light chain in, 2001
CX3CR1 mediates homing of MHC class II–positive cells to (mouse), 1568
in diabetic Goto-Kakizaki rat, 590
expression of Th-1 chemokines and receptors in mouse model of dry eye, 2561
flagellin pretreatment modulates immune response to Pseudomonas infection, 4664
functions of MUC16 in, 4509
HSV-1–dependent apoptosis in, 4980
inhibition of TGF-β2 production by extracellular matrix, 1061
notch signaling in differentiation and proliferation of, 3576
PAF and repressor effect of Sp1 in expression of MMP-9 in, 1931
PHSRN peptide stimulation of migration of, 1110
protective effect of caffeine against UV-induced apoptosis in, 652
Corneal femtosecond laser keratotomy, wound healing after (rabbit), 2068
localization of ZO-1 in nucleolus of, 2043
mitomycin C upregulates chemokine expression in, 2009
modulation of CD8+ cytotoxic T lymphocyte effector function by fibroblasts derived from immunoprivileged cornea (mouse), 2194
morphology of organized ECM deposition by, 4050
regulation by ECM mechanical properties, 5030
Corneal implants, tissue-engineered, innervation of (pig), 3537
allergic conjunctival inflammation and allogeneic response to donor cornea, 4044
CCR1 deletion prolongs allograft survival (mouse), 1228
corneal innervation and cellular changes after, 621
episcleral cyclosporine implant for keratoplasty rejection, 2023
NGF gene therapy improves allograft survival (rat), 1043
photo cross-linkable biodendrimers as ophthalmic adhesives for, 2037
after corneal femtosecond laser keratotomy (rabbit), 2068
carboxymethylcellulose in, 1559
CD18 integrins and neutrophil–keratocyte interactions during (mouse), 5023
in diabetic Goto-Kakizaki rat, 590
laser-activated solder for sealing corneal wounds, 1038
light-scattering and ultrastructure of healed penetrating wounds (rabbit), 157
lysophosphatidic acid and EGFR signaling in, 636
photo cross-linkable biodendrimers as ophthalmic adhesives for wound repair, 2037
Cortical defects in amblyopia, 1575
Cortical organization and optic disc damage in glaucoma, 733
cytotoxicity of triamcinolone acetonide on RPE cells, 2792
retinal toxicity of intravitreal triamcinolone acetonide (rabbit), 390
triamcinolone acetonide effects on leukocyte–endothelium interactions in ischemic retina (rat), 2831
triamcinolone acetonide-mediated oxidative injury, compared with dexamethasone, 5742
Cost-effectiveness of cycloplegic agents in Nigerian children, 1025
CRYAA gene, genetic heterogeneity in microcornea-cataract, 3937
CRYBB1, homozygous deletion in congenital cataract, 2208
CRYGD gene, genetic heterogeneity in microcornea-cataract, 3937
Cryopreservation, and genetic modification of cultured corneal endothelial cells, 3056
γD-crystallin–associated protein aggregation and lens fiber cell denucleation (mouse), 3719
degradation of C-terminal αA-crystallins in cataract, 4200
target protein sits in fenestrations of α-crystallin, 2695
actin cytoskeletal integrity and MMP-2 activation in TM cells, 2105
activation of BMP canonical signaling pathway, 5058
adenosine and intercellular calcium wave in corneal endothelial cells, 1518
β-adrenergic receptors in inflammatory marker expression in Müller cells, 5276
analysis of RPE cells exposed to REF-1/TFPI-2, 516
antiapoptotic effects of thymosin β-4 on corneal epithelial cells, 27
antitumor action of neurokinin-1 receptor antagonist in retinoblastoma, 2775
apoptotic response of HSV-1 in corneal epithelial cells, 789 (erratum, 1000)
Bcl-xL in survival of RPE cells, 3846
benzalkonium chloride–induced dephosphorylation of myosin light chain in corneal epithelial cells, 2001
bilberry anthocyanins in oxidative stress defense, 2343
BMP-7 is antagonist of TGF-β2 in TM cells, 715
c-Met and EGFR in RPE wound healing, 2242
calpains in RGC death, 5420
CaMKIIαB mediates survival response in RGCs, 3854
carboxymethylcellulose in corneal epithelial wound healing, 1559
caspase-8–mediated apoptosis in RPE cells, 3341
caspase activation by 7-ketocholesterol in retinal neurosensory cells, 1362
characterization of antigen-presenting cells in fresh and cultured human corneas, 4459
circadian control of tyrosine phosphorylation of cGMP-gated ion channels in chick photoreceptors, 901
cryopreservation and genetic modification of cultured corneal endothelial cells, 3056
cytotoxicity of triamcinolone acetonide on RPE cells, 2792
θ-defensin in murine HSV-1 keratitis, 5118
DHA effect on retinal endothelial caveolae, 18
double-stranded RNA-dependent protein kinase in ER stress–induced retinal neuron damage, 3729
ECM gene alternative splicing by TM cells in response to mechanical stretching, 1164
effect of inflammatory cytokines on RPE proliferation/migration, 5722
emodin suppression of ocular surface inflammatory reaction, 5013
endogenous bone marrow–derived cells express RPE cell markers, 4321
endostatin generation by limbal epithelial cells on amniotic membrane, 644
endothelin-1–mediated signaling in expression of MMPs and TIMPs in astrocytes, 3737
expression of IDO in human corneal cells, 4148
fate of limbal epithelial progenitor cells during ex vivo expansion, 605
fractalkine mediation of ocular angiogenesis, 5290
functions of MUC16 in corneal epithelial cells, 4509
gene expression profiles of donor-matched vascular endothelial cells, 2676
glucocorticoid receptor activation and signal transduction pathways in lens epithelial cells, 1724
GM-CSF expression in herpetic stromal keratitis, 277
gremlin and epithelial-to-mesenchymal transition in PVR, 4291
histone deacetylase and neuronal differentiation, 2845
hypoxia-enhanced expansion of limbal epithelial cells, 3586
identification of RLBP1 gene promotor, 3872
IGF in RPE cell tractional force generation, 1892
inhibition of corneal epithelial TGF-β2 production by extracellular matrix, 1061
in vitro generation of functional lens-like structures, 1245
intracellular events in retinal glial cells exposed to ICG and BBG, 4426
intracellular phospholipases A2 in photoreceptor outer segment phagocytosis, 1401
JAM-A in corneal endothelium and RPE, 3928
lactate causes NF-κB activation and CD44 shedding in cultured TM cells, 1615
laminin regulation of α6 integrin gene expression, 3490
lens cell survival in stressed capsular bag, 2701
lens epithelial cell response to quercetin and DMSO, 3714
localization of ZO-1 in nucleolus of corneal fibroblasts, 2043
loss of α3(IV) collagen in activated corneal keratocytes, 627
lysophosphatidic acid and EGFR signaling in corneal wound healing, 636
mechanisms of immune system activation in glaucoma, 705
miRNA expression in human and rat retinas, 3962
mitochondrial fission in differentiated RGC-5 cells, 2145
mitomycin C upregulates chemokine expression in corneal fibroblasts, 2009
MMP-14 and TIMP-2 overexpression protects against oxidant injury in RPE, 5662
MMP and TIMP expression in human lens cells, 4192
morphology of organized ECM deposition by human corneal fibroblasts, 4050
mutant ND4 induces optic neuropathy (mouse), 1
notch signaling in corneal epithelial cell differentiation and proliferation, 3576
novel in vitro model of posterior capsular opacity, 4679
organ culture and Optisol-GS storage of cultured human limbal epithelial cells, 5484
oxidative stress in hydrostatic pressure–induced RGC damage, 4580
PAF and repressor effect of Sp1 in expression of MMP-9 in corneal epithelial cells, 1931
PDGF-C in proliferative vitreoretinopathy, 2335
phenotype of limbal epithelial stem cells, 144
photoreceptor protective effect of minocycline, 412
plasminogen activators cause death of RGCs, 1884
positive feedback regulation between MMP-9 and VEGF in RPE cells, 4360
prevention of excitotoxicity in RGCs by (+)pentazocine, 4785
protective effect of lipoic acid against acrolein toxicity in RPE cells, 339
protective effects of caffeine against UV-induced apoptosis in corneal epithelial cells, 652
protective effects of uridine on cornea in rabbit dry eye model, 1102
purinergic receptor–mediated regulation of lens connexin43, 4177
RAGE ligand upregulation of VEGF secretion in ARPE-19 cells, 1355
regulation of corneal fibroblasts by ECM mechanical properties, 5030
regulation of IL-8 by S. aureus in conjunctival cells, 270
reproducibility of endothelial assessment, 2062
retinoic acids and cataractogenesis, 2224
Rho-kinase signaling in Tenon’s capsule fibroblasts, 2152
role of MEK1 in 15(S)-HETE–induced angiogenesis, 4930
RS1 mutants associated with X-linked retinoschisis, 2491
secretion of cornea-like tissue in vitro by stem cells, 5038
sodium 4-phenylbutyrate corrects myocilin misfolding, 1683
surface bacterial flora in normal and dry eyes, 5616
surfactant proteins A and D in human tear fluid and lacrimal system, 3945
synergism of cytokine induction of MMP-3 in TM, 2634
TGF-β1 repression of E-cadherin via Slug expression in lens epithelium, 2708
thrombin inhibition of intercellular Ca2+ wave propagation in corneal endothelial cells, 120
thyroxine-ameliorated oxidative stress in lens epithelial cells, 3698
tissue transglutaminase expression in subconjunctival fibroblasts, 1952
TLR-3 and -9 in human corneal myofibroblasts, 3069
triamcinolone acetonide-mediated oxidative injury, compared with dexamethasone, 5742
TRPC channels mediate basal calcium entry in RPE cells, 5767
two spontaneous human Müller cell lines from diabetic donors, 874
Wnt signaling during photoreceptor degeneration, 5733
Cyclic ADP-ribose–dependent calcium signaling pathway in bovine rod outer segments, 978
Cycloplegic agents, cost-effectiveness in Nigerian children, 1025
Cyclosporine, episcleral implant for keratoplasty rejection, 2023
CYP1B1, glaucoma-associated mutations in POAG and PACG phenotypes, 5439
CYP4V2 mutations, genotype–phenotype analysis of Bietti’s crystalline dystrophy in patients with, 5212
Cystine, regional differences in accumulation in rat lens, 1253
Cytokeratin 18, as biomarker of early hepatic metastasis from uveal melanoma, 4399
dacryoadenitis in IL-4 deficient MRL/MpJ mice, 5624
DHA effect on retinal endothelial caveolae, 18
effect of inflammatory cytokines on RPE proliferation/migration, 5722
endogenous TNF-α suppression of neovascularization in corneal stroma (mouse), 3051
GM-CSF expression in herpetic stromal keratitis, 277
IL-1 gene cluster polymorphisms and glaucoma in Chinese subjects, 2123
multiplex bead analysis of vitreous humor, 2203
regulation of IL-8 by S. aureus in conjunctival cells, 270
role of soluble TNF receptors for TNF-α in uveitis, 3246
synergism of cytokine induction of MMP-3 in TM, 2634
Th1/Th2 cytokine profile in primary intraocular B-cell lymphoma (mouse), 3223
TNF-α–induced apoptosis in murine CMV retinitis, 1691
Cytomegalovirus (CMV) retinitis
iNOS and CMV spread in retina (mouse), 285
TNF-α–induced apoptosis in (mouse), 1691
Early-onset severe retinal dystrophy, Apex microarray genotyping of patients with Leber congenital amaurosis and, 5684
Eicosapentaenoic acid (EPA) prevents choroidal neovascularization in mice, 4328
Elastin maturation, in optic nerve head and astrocytes, population differences in, 3209
bidirectional modulation of primary visual cortex excitability, 5782
effect in acute-phase optic nerve injury (rat), 2356
protection of photoreceptors by (rat), 4725
Electromyography, blink recovery in Bell’s palsy, 203
Electronic medical records system for clinical research and the EMR–EDC interface (new developments), 4383
Electroretinography (ERG)
in CNGB3 achromatopsia, 3864
CNTF-induced cellular changes in murine RP, 1389
in dominant optic atrophy with OPA1 mutations, 820
effect of spectral characteristics of Ganzfeld stimuli on photopic negative response (monkey), 4818
ERG photostress test in evaluation of retinal function in ARM, 2806
focal macular ERG and angiographic findings after PDT, 2254
intramembrane determinant of peripherin/rds function for photoreceptor disk morphogenesis (mouse), 2975
memantine effects in diabetic retinopathy (rat), 5152
of central retinal function in advanced RP, 1312
effect of acute hypoxia and hyperoxia on, 3405
fellow eye losses in asymmetric glaucoma, 2626
implicit time delays and adaptation in diabetic patients, 5250
patterns of cone degeneration in RP, 383
neurotrophic factors minimize renal toxicity of verteporfin PDT (rat), 430
ocular hypopigmentation in Rab38cht/cht mice, 3905
oscillatory potentials of dark-adapted ERG in ROP (rat), 5788
pathological and electrophysiological features of canine cone–rod dystrophy, 4240
pattern ERG monitoring of RGC dysfunction in murine glaucoma, 745
phenotype of retinal degeneration in persons with RDH12 mutations, 1824
preclinical safety evaluation of intravitreal VEGF antibody injection (rabbit), 1773
preservation of macular oscillatory potentials in RP, 3312
protective effect of TEMPOL derivatives against light-induced retinal damage (rat), 1900
pseudoxanthoma elasticum with generalized retinal dysfunction, 4250
restoration of visual responses in aged dystrophic rats after channelopsin-2 gene transfer, 3821
retinal toxicity of intravitreal triamcinolone acetonide (rabbit), 390
sensitivity to light-induced damage in autosomal dominant retinal disease (mouse), 1942 (erratum, 3436)
SIRT1 neuroprotection in experimental optic neuritis (mouse), 3602
tolerance to retinal ischemia by hypoxic preconditioning (mouse), 1735
truncated rhodopsin in rod function and degeneration (moue), 2868
EMD478761 implant, angiogenesis inhibition by, 5184
Emmetropia, blur adaptation in myopia and, 2932
form-deprivation myopia and effects of foveal ablation on (monkey), 3914
temporal constraints in infant monkeys, 957
Emodin, suppression of ocular surface inflammatory reaction, 5013
Endocannabinoids, in retinal damage after high IOP-induced ischemia in rats, 2997
Endoplasmic reticulum (ER) stress
activation in degenerating photoreceptors (mouse), 5191
double-stranded RNA-dependent protein kinase in retinal neuron damage induced by, 3729
Endostatin, generation by limbal epithelial cells on amniotic membrane, 644
adenosine and intercellular calcium wave in, 1518
cultivated corneal endothelial cell sheet transplantation (monkey), 4519
cultured, cryopreservation and genetic modification of, 3056
isolation, preservation, and expansion of, 614
reproducibility of endothelial assessment, 2062
thrombin inhibition of intercellular Ca2+ wave propagation in, 120
two semiautomated methods for evaluating endothelial cells of eye bank corneas, 3077
DHA effect on retinal endothelial caveolae, 18
donor-matched, gene expression profiles of, 2676
novel alternatively spliced isoforms of RTEF-1 in, 3775
retinal, hyperglycemia regulation of IGF-1 signaling in, 3878
triamcinolone acetonide effects on leukocyte–endothelium interactions in ischemic retina (rat), 2831
Endothelin-1–mediated signaling in expression of MMPs and TIMPs in astrocytes, 3737
Endotoxin, visual system vulnerability to prenatal exposure to (sheep), 472
Environmental conditions, dry eye and, 4026
EphB2 and ephrin-B2 upregulation at optic nerve head in glaucomatous mice with axon loss, 5567
astigmatism in 12-year-old Australian children, 73
Chlamydia pneumoniae infection and AMD, 4007
Inflammatory markers and hemostatic factors in ARM, 1983
British Infantile and Childhood Glaucoma Eye Study, 4100
CFH gene variants, smoking, and AMD risk in Japanese population, 5315
ethnic differences in impact of parental myopia, 2520
ethnic differences in macular pigment density and distribution, 3783
hyperhomocysteinemia and low methionine stress as risk factors for central retinal venous occlusion, 1441
IL-1 gene cluster polymorphisms and glaucoma in Chinese subjects, 2123
prevalence of early and late AMD in rural Northern India, 1007
prevalence of lens opacities in North India, 88
Los Angeles Latino Eye Study, retinopathy in persons without diabetes, 4019
macular pigment optical density in the elderly, 1458
ocular dominance, laterality, and refraction in Singaporean children, 3533
parental ocular and activity history and future myopia, 3524
population study of X-linked RP, 4012
Projeto Glaucoma, glaucoma prevalence in South Brazilian population, 4974
visual field loss and risk of falls in older adults, 4445
visual impairment and motor vehicle crashes among older drivers, 1483
Shihpai Eye Study, correctable visual impairment in elderly Taiwanese, 1032
Epidermal growth factor receptor (EGFR)
and c-Met in RPE wound healing, 2242
and lysophosphatidic acid in corneal wound healing, 636
ciliary, fluid transport across, 321
comparison of gene expression in human conjunctiva and cornea, 2050
antiapoptotic effects of thymosin β-4 on, 27
apoptotic response of HSV-1 in, 789 (erratum, 1000)
benzalkonium chloride–induced dephosphorylation of myosin light chain in, 2001
CX3CR1 mediates homing of MHC class II–positive cells to (mouse), 1568
in diabetic Goto-Kakizaki rat, 590
expression of Th-1 chemokines and receptors in mouse model of dry eye, 2561
flagellin pretreatment modulates immune response to Pseudomonas infection, 4664
functions of MUC16 in, 4509
HSV-1–dependent apoptosis in, 4980
inhibition of TGF-β2 production by extracellular matrix, 1061
notch signaling in differentiation and proliferation of, 3576
PAF and repressor effect of Sp1 in expression of MMP-9 in, 1931
PHSRN peptide stimulation of epithelial cell migration, 1110
protective effect of caffeine against UV-induced apoptosis in, 652
connexins and lens epithelial cell proliferation (mouse), 5630
glucocorticoid receptor activation and signal transduction pathways in, 1724
in vitro generation of functional lens-like structures, 1245
response to quercetin and DMSO, 3714
TGF-β1 repression of E-cadherin via Slug expression in, 2708
thyroxine-ameliorated oxidative stress in, 3698
transcytotic passage of albumin through, 1237
fate of limbal epithelial progenitor cells during ex vivo expansion, 605
hypoxia-enhanced expansion of, 3586
analysis of cells exposed to REF-1/TFPI-2, 516
Bcl-xL in survival of, 3846
c-Met and EGFR in RPE wound healing, 2242
caspase-8–mediated apoptosis in, 3341
controlling RPE injury after experimental retinal detachment (mouse), 1348
cytotoxicity of triamcinolone acetonide on, 2792
effect of inflammatory cytokines on RPE proliferation/migration, 5722
endogenous bone marrow–derived cells express RPE cell markers, 4321
gene expression profiling of zebrafish embryonic RPE, 881
glypican 4, bactericidal/permeability-increasing protein in, 5750
homeostatic regulation of photoreceptor cell integrity (Proctor Lecture), 4866
IGF in RPE cell tractional force generation, 1892
in vivo imaging of RPE mosaic in diseased retina, 2297
JAM-A in corneal endothelium and, 3928
lipid peroxidation and RPE lysosomal dysfunction, 1342
MMP-14 and TIMP-2 overexpression protects against oxidant injury in, 5662
ornithine cytotoxicity in, 464
positive feedback regulation between MMP-9 and VEGF in, 4360
posterior pole injury and peripheral RPE proliferation (pig), 355
protective effect of lipoic acid against acrolein toxicity in, 339
rapid recruitment of TIP47 in (mouse), 2858
RPE and CD4 T-cell interaction in T-cell anergy (mouse), 4654
selective RPE targeting with laser scanner (rabbit), 1782
somatic ablation of Lrat gene in mouse RPE, 5377
spermine cytotoxicity in, 455
thrombin-induced VEGF expression in, 2738
TRPC channels mediate basal calcium entry in RPE cells, 5767
vitreous modulation of gene expression in, 1853
transplantable rabbit carrier-free epithelial sheets, 597
Erg-1 (ZENK), relative axial myopia in Egr-1 knockout mice, 11
Errata, 17, 485, 1000, 1917, 1951, 2083, 2966, 3436, 4900, 5359
Erythropoietin, neuroprotective effect on RGCs in glaucoma mice, 1212
motion-detection asymmetries in esotropic and normal infants, 5523
progression in infancy, 661
Esthesiometry, noncontact, corneal innervation and sensitivity in patients with dry eye, 173
Estrogen receptor α gene, polymorphisms associated with AMD, 1012
Everolimus, modulation of cholesterol homeostasis by antiproliferative drugs in pterygium fibroblasts, 3450
genome-wide scan of, 4136
proteomic analysis of exfoliation deposits, 1447
Experimental autoimmune uveitis (EAU)
CD8 regulatory T cells in (mouse), 2178
IL-17+ interphotoreceptor retinoid-binding protein-specific T cells in (mouse), 4153
role of apoptosis in resolution of (rat), 5091
suppression by anti-LFA-1α Ab (mouse), 2667
Extracellular matrix (ECM), 1061
ECM gene alternative splicing by TM cells in response to mechanical stretching, 1164
effect of VEGF-A on expression of profibrotic growth factor and ECM genes in retina (rat), 4267
inhibition of corneal epithelial TGF-β2 production by, 1061
laminin regulation of α6 integrin gene expression, 3490
morphology of organized ECM deposition by human corneal fibroblasts, 4050
regulation of corneal fibroblasts by ECM mechanical properties, 5030
secretion of cornea-like tissue in vitro by stem cells, 5038
Extraocular muscles (EOMs)
density and distribution of neuromuscular junctions in normal and botulinum toxin–treated EOMs (rabbit and monkey), 3594
fascicular specialization in human and monkey rectus muscles, 3089
horizontal rectus muscle anatomy in strabismic monkeys, 2576
layer-specific differences in M-bands of (rat), 1119
MRI in Duane-radial ray syndrome, 5505
oculomotor nerve in congenital fibrosis of EOMs and congenital oculomotor palsy, 1601
sideslip of medial rectus muscle during vertical eye rotation, 4527
organ culture and Optisol-GS storage of cultured human limbal epithelial cells, 5484
two semiautomated methods for evaluating endothelial cells of eye bank corneas, 3077
Eye development and growth
apolipoprotein A-I and E in developing mouse retina, 1815
effects of foveal ablation on emmetropization and form-deprivation myopia (monkey), 3914
effects of IVF on structural features of neonatal eyes, 5454
expression profiling of retinoschisin-deficient retina in postnatal mouse development, 891
gene expression profiling of zebrafish embryonic RPE, 881
histogenesis of intravitreal membrane and secondary vitreous (mouse), 1923
immaturities limiting infant binocular stereopsis, 1424
keratan sulfate in developing avian cornea, 3083
laminins essential for basement membrane integrity (zebrafish), 2483
opsin expression during retinal development in salmonid fishes, 866
Pax6 required for postnatal eye development (mouse), 3292
postnatal corneal transparency, keratocyte cell cycle exit and expression of ALDH1A1 (rabbit), 6274061
simultaneous defocus integration during refractive development (chick), 5352
structural specializations emerging late in mouse lens fiber cell differentiation, 3269
temporal constraints on experimental emmetropization in infant monkeys, 957
Eye examinations, attitudes of African-Americans about, 1989
Eye-hand coordination, prehension deficits in amblyopia, 1139
blink recovery in Bell’s palsy, 203
changes in dynamic properties during vertical saccades in acute superior oblique palsy (monkey), 2612
cross-axis, in primates with A pattern strabismus, 665
horizontal saccade disconjugacy in strabismic monkeys, 3107
infantile nystagmus adapts to visual demand, 2089
Listing’s plane shift due to semicircular canal stimulation, 2076
oculomotor control in premature children, 2595
blink recovery in Bell’s palsy, 203
influence of eyelid morphology on corneal shape, 112
Ganglion cells, retinal (RGCs)
calpains in RGC death, 5420
CaMKIIαB mediates survival response in, 3854
chemotactic effect of CNTF on macrophages in RGC survival and axonal regeneration (rat), 4257
differentiation of retinal stem cells transplanted into murine RP models, 446
double-stranded RNA-dependent protein kinase in ER stress–induced retinal neuron damage, 3729
IOP-dependent RCG dysfunction in glaucomatous DBA/2J mice, 4573
mitochondrial fission in differentiated RGC-5 cells, 2145
neuroprotective effect of erythropoietin on RGCs in glaucoma mice, 1212
optineurin mutant induces death of, 1607
oxidative stress in hydrostatic pressure–induced RGC damage, 4580
pattern ERG monitoring of RGC dysfunction in murine glaucoma, 745
plasminogen activators cause death of, 1884
prevention of excitotoxicity in RGCs by (+)pentazocine, 4785
progressive dysfunction in DBA/2J mouse model of glaucoma, 4564
retinal phenotypes in mammalian ciliary body after injury of (mouse), 5266
synaptic contact between melanopsin-containing RGCs and rod bipolar cells (rat), 3812
transgenic analysis of rodent anterior ischemic optic neuropathy–induced RGC stress and loss (mouse), 2304
Gas jets in pneumatic retinopexy (pig), 2734
Gelatinous drop-like corneal dystrophy
cell junction–related proteins in, 1095
TACSTD2 mutations in, 4490
astigmatism in 12-year-old Australian children, 73
on color vision defects in asymptomatic carriers of Leber’s hereditary optic neuropathy, 2362
retinal vascular caliber and children’s ethnicity, gender, and birth parameters, 1018
ABCA4 mutations in severe retinopathies in Spanish patients, 985
absence of 4–1BB gene function and lacrimal gland inflammation (mouse), 4608
Apex microarray genotyping of patients with Leber congenital amaurosis and early-onset severe retinal dystrophy, 5684
bestrophin mutations in canine multifocal retinopathy, 1959
CERKL mutation in autosomal recessive RD among Yemenite Jews, 5431
CFH gene variants, smoking, and AMD risk in Japanese population, 5315
chloride channel activity of bestrophin mutants causing macular degeneration, 4694
γD-crystallin–associated protein aggregation and lens fiber cell denucleation (mouse), 3719
disease course of patients with X-linked RP due to RPGR mutations, 1298
ERG findings in dominant optic atrophy with OPA1 mutations, 820
genetic heterogeneity in microcornea-cataract, 3937
genetic mapping of myopia susceptibility loci, 4924
genotype-phenotype correlations in Axenfeld-Rieger malformation and glaucoma with FOXC1 and PITX2 mutations, 228
genotype–phenotype analysis of Bietti’s crystalline dystrophy in patients with CYP4V2 mutations, 5212
glaucoma-associated CYP1B1 mutations in POAG and PACG phenotypes, 5439
GNPTAB deficiency (mouse), 5221
homozygosity for novel ABCA4 founder splicing mutation associated with Stargardt-like disease, 4308
homozygous CRYBB1 deletion in congenital cataract, 2208
identifying novel mutations in Leber congenital amaurosis and juvenile RP, 5690
inner retinal abnormalities in X-linked RP with RPGR mutations, 4759
in Japanese patients with Norrie disease and familial exudative vitreoretinopathy, 1276
late-onset cone degeneration induced by Rds mutation and gene rescue (mouse), 5397
macular pigment and lutein supplementation in ABCA4 disease, 1319
mutant ND4 induces optic neuropathy (mouse), 1
mutation screening for Leber congenital amaurosis, 5653
novel CACNA1F mutation causes Åland Island eye disease, 2498
novel mutation in carbonic anhydrase IV gene that causes RP, 3459
novel TULP1 mutation causing Leber congenital amaurosis or early onset RD, 5160
nuclear and mitochondrial analysis of primary angle-closure glaucoma, 5591
ocular hypopigmentation in Rab38cht/cht mice, 3905
optic nerve head in Myocilin glaucoma, 238
optineurin mutant induces death of RGCs, 1607
phenotype of retinal degeneration in persons with RDH12 mutations, 1824
population study of X-linked RP, 4012
PRPF31 mutations in autosomal dominant RP, 1330
RDH12 and RPE65 differ in disease expression, 332
retinal alterations in zebrafish laminin mutants, 2887
RNFL thinning in autosomal dominant optic atrophy with OPA1 mutations, 4079
RS1 mutants associated with X-linked retinoschisis, 2491
T1799A BRAF mutation in iris melanoma, 4897
TACSTD2 mutations in gelatinous drop-like corneal dystrophy, 4490
208delG mutation in FSCN2 in Chinese individuals, 530
UBIAD1 mutations in Schnyder crystalline corneal dystrophy, 5007
zebrafish cone photoreceptor–specific promoter and genetic rescue of achromatopsia, 522
AAV-mediated expression targeting of rods and cones with human rhodopsin kinase promoter (mouse), 3954
antioxidant gene therapy in optic neuritis (mouse), 5360
late-onset cone degeneration induced by Rds mutation and gene rescue (mouse), 5397
NGF gene therapy improves corneal allograft survival (rat), 1043
retinoschisin gene therapy in Rs1h-KO mouse, 3837
RS1 mutants associated with X-linked retinoschisis and, 2491
restoration of visual responses in aged dystrophic rats after channelopsin-2 gene transfer, 3821
with self-complementary adeno-associated virus vectors, 3324
comparison of gene expression in human conjunctiva and cornea, 2050
corneal virulence of Candida albicans strains deficient in Tup1-regulated genes (mouse), 2535
cryopreservation and genetic modification of cultured corneal endothelial cells, 3056
ECM gene alternative splicing by TM cells in response to mechanical stretching, 1164
epigenetic inactivation of RASSF1a in uveal melanoma, 486
estrogen receptor α gene polymorphisms associated with AMD, 1012
expression profiling of retinoschisin-deficient retina in postnatal mouse development, 891
familial aggregation of refractive error in Old Order Amish, 4002
form-deprivation myopia in chick and retinal gene expression, 3430
gene expression analysis of photoreceptor cell loss in Bbs4-knockout mice, 3329
gene expression in experimental glaucoma and optic nerve transection (rat), 5539
gene expression profiles of donor-matched vascular endothelial cells, 2676
gene expression profiling of zebrafish embryonic RPE, 881
genetic ablation of cone photoreceptors and retinal fold elimination in rd7 mouse, 2799
genetic determinant of retinal degeneration on mouse chromosome 6, 405
genetic variations among ocular isolates of Staphylococcus epidermidis, 3239
genome-wide scan of exfoliation syndrome, 4136
heredity of small hard drusen in twins aged 20–46 years, 833
heritability of pathologic features in glaucoma, 3669
heritable features of optic disc, 2469
HSP-70/Hom gene polymorphisms and uveitis in patients with sarcoidosis, 3019
IL-1 gene cluster polymorphisms and glaucoma in Chinese subjects, 2123
inheritance of peripapillary atrophy, 2529
interferon gamma receptor 1 polymorphisms and atopic cataracts, 583
laminin regulation of α6 integrin gene expression, 3490
of Leber’s congenital amaurosis, 4284
linkage analysis in Duane’s retraction syndrome, 189
linkage mapping of ovine microphthalmia to chromosome 23, 3506
linkage replication of MYP12 locus in myopia, 4433
LOC387715 polymorphism and AMD, 1128
novel retinal and cone photoreceptor transcripts, 5388
optic nerve head gene expression after exposure to elevated IOP in rat glaucoma model, 3161
persistent hyperplastic primary vitreous due to somatic mosaic deletion of Arf (mouse), 491
of pigment changes and geographic atrophy, 3005
prognosis-determinant candidate genes in pterygia, 3566
promoter methylation status of multiple genes in uveal melanoma, 4403
roles of PAX6 and SOX2 in myopia, 4421
and susceptibility to oxygen-induced retinopathy (rat), 1761
targeted transgene expression in retinal Müller glia using lentiviral vectors, 1844
transcriptome of Müller cells and two spontaneous cell lines, 5229
vitreous modulation of gene expression in RPE cells, 1853
Geographic atrophy, genetics of pigment changes and, 3005
Geriatric population. See also Age effects
attitudes of African-Americans about eye examinations, 1989
CFH gene variants, smoking, and AMD risk in Japanese population, 5315
circulating hematopoietic stem cells in neovascular AMD, 5464
computer-based test for optimal visual acuity in AMD, 4838
contrast sensitivity changes in glaucoma and normal aging, 2115
LOC387715 polymorphism and AMD, 1128
macular pigment optical density in, 1458
macular temporal responsiveness in normal aging and ARM, 4811
multifocal spectacles and tripping in, 1466
retinal abnormalities in early Alzheimer’s disease, 2285
retinal vascular network geometry and cognitive ability in, 1995
Shihpai Eye Study, correctable visual impairment in elderly Taiwanese, 1032
visual field loss and risk of falls in older adults, 4445
visual impairment and motor vehicle crashes among older drivers, 1483
visual spatial integration in, 2940
Gipson, Ilene K., 2007 recipient of Friedenwald Award, 4390
GJA8 gene, genetic heterogeneity in microcornea-cataract, 3937
Glare, pupil size and retinal straylight, 2375
advanced glycation end products in, 1201
antiscarring effects of Y-27632 in glaucoma filtration surgery (rabbit), 5549
APP and amyloid-β immunoreactivity in glaucomatous mouse retinas, 5085
asymmetric, fellow eye losses in, 2626
automated segmentation of optic disc from stereo color photographs, 1665
British Infantile and Childhood Glaucoma Eye Study, 4100
ceruloplasmin upregulation in (mouse), 727
chondroitin sulfate-derived disaccharide protects retinal cells from elevated IOP (rat), 1181
contrast sensitivity changes in normal aging and, 2115
CYP1B1 mutations in POAG and PACG phenotypes, 5439
decreasing visual field test–retest variability in, 1627
diagnostic accuracy of confocal scanning laser ophthalmoscopy, 214
effect of atypical birefringence patterns on detection using SLP with variable corneal compensation, 223
effect of disc size and disease severity on diagnostic accuracy of Heidelberg Retina Tomograph Glaucoma Probability Score, 2653
imaging comparison of optic disc and RNFL in, 2644
OCT and Heidelberg retinal tomography parameters in detecting early and moderate glaucoma, 3138
rule extraction for detection with OCT, 244
using scanning laser polarimetry with enhanced corneal compensation, 3146
detection with dichoptic multifocal VEPs, 4590
effect of 15-keto latanoprost on IOP and aqueous humor dynamics (monkey), 4143
effects of IOP reduction on perimetric variability in, 4557
effects of TGF-β2, BMP-4, and gremlin in TM, 1191
elevated alkaline phosphatase in glaucomatous TM, 3184
EphB2 and ephrin-B2 upregulation at optic nerve head in glaucomatous mice with axon loss, 5567
experimental, Hsp27 phosphorylation in (rat), 4129
gene expression in experimental glaucoma and optic nerve transection (rat), 5539
genotype-phenotype correlations in Axenfeld-Rieger malformation and glaucoma with FOXC1 and PITX2 mutations, 228
heritability of pathologic features in, 3669
and IL-1 gene cluster polymorphisms in Chinese subjects, 2123
impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma, 5558
in vitro studies of antiglaucomatous prostaglandin analogues, 4123
IOP-dependent RCG dysfunction in glaucomatous DBA/2J mice, 4573
mechanisms of immune system activation in, 705
mental effort and independent mobility in, 3988
multifocal VEP vs. standard automated perimetry in ocular hypertension and, 1173
Myocilin, optic nerve head in, 238
neuroprotective effect of erythropoietin on RGCs in mice, 1212
normal-tension, circadian fluctuation of mean ocular perfusion pressure as risk factor for, 104
novel spatial filter to monitor visual field progression in, 251
nuclear and mitochondrial analysis of primary angle-closure glaucoma, 5591
OCT and histology of RNFL thickness in (monkey), 3645
optic nerve head gene expression after exposure to elevated IOP in rat, 3161
oxidative stress in hydrostatic pressure–induced RGC damage, 4580
pattern ERG monitoring of RGC dysfunction in (mouse), 745
pharmacy claims data to study medication adherence in, 5052
preperimetric, Stratus OCT in, 1635
prevalence in South Brazilian population, 4974
progressive RGC dysfunction in DBA/2J mouse model of, 4564
relationship between visual field sensitivity and RNFL thickness measured by OCT, 258
repeatability of confocal scanning laser ophthalmoscopy, SLP, and OCT in, 1156
reproducibility of anterior chamber angle measurements by OCT, 3683
retinotopic organization of primary visual cortex in, 733
risk of falls and motor vehicle collisions in, 1149
RNFL thickness after acute primary angle closure measured with OCT, 1659
SLP and OCT in normal and glaucomatous eyes, 2099
sodium 4-phenylbutyrate corrects myocilin misfolding in, 1683
sources of motion-sensitivity loss in, 2913
stronger structure–function relationship with enhanced corneal compensation than with variable corneal compensation in SLP, 1651 (erratum, 1917)
structure vs. function in, 3662
3-D histomorphometry of early glaucomatous monkey optic nerve head, 5068
3-D histomorphometry of normal and early glaucomatous monkey optic nerve head, 3195, 4597
visual field clustering with machine learning classifiers, 5582
visual field progression determined by Monte Carlo simulation in, 1642
Glaucoma Adherence and Persistency Study, pharmacy claims data to study glaucoma medication adherence, 5052
Glial cell-derived neurotrophic factor (GDNF)
Ret activation does not protect from light-induced damage (mouse), 5199
stimulation of rods and dopaminergic amacrine cells (chick), 5306
contributions to retinal detachment–induced photoreceptor degeneration (mouse), 2760
differentiation of retinal stem cells transplanted into murine RP models, 446
retinal, intracellular events associated with ICG and BBG, 4426
targeted transgene expression in retinal Müller glia using lentiviral vectors, 1844
two spontaneous human Müller cell lines from diabetic donors, 874
Glucocorticoid receptor, and signal transduction pathways in lens epithelial cells, 1724
Glucose-6-phosphate dehydrogenase (G6PD), in retinal vein occlusion, 2747
Glutamic acid, intramembrane determinant of peripherin/rds function for photoreceptor disk morphogenesis (mouse), 2975
Glutathione, effect on binding of kynurenine to lens proteins, 3705
Glycine uptake in lens core, role of GLYT2 in (rat), 5142
choroidal regulation of scleral synthesis during recovery from induced myopia (chick), 2957
keratan sulfate in developing avian cornea, 3083
levels in tree shrew sclera during induced myopia development and recovery, 2947
Glypican 4, bactericidal/permeability-increasing protein in RPE, 5750
GNPTAB deficiency (mouse), 5221
Goblet cells, conjunctival
density after LASIK procedures, 2570
neurotrophins in (rat), 1543
Graft-versus-host disease (GVHD), chronic, HSP47 in lacrimal gland pathology in, 1079
Granulocyte macrophage colony–stimulating factor (GM-CSF), expression in herpetic stromal keratitis, 277
Gremelin, effects of TGF-β2, BMP-4, and gremlin in TM, 1191
Gremlin and epithelial-to-mesenchymal transition in PVR, 4291
Gyrate atrophy of choroid and retina
ornithine cytotoxicity in RPE cells, 464
spermine cytotoxicity in RPE cells, 455
bacterial transcytosis across conjunctival M cells (guinea pig), 2172
CD8 regulatory T cells in experimental autoimmune uveitis (mouse), 2178
CX3CR1 mediates homing of MHC class II–positive cells to mouse corneal epithelium, 1568
IL-17+ interphotoreceptor retinoid-binding protein-specific T cells in EAU (mouse), 4153
Inflammatory markers and hemostatic factors in ARM, 1983
lipopeptide vaccines to prevent ocular herpes infection, 4643
mechanisms of immune system activation in glaucoma, 705
modulation of CD8+ cytotoxic T lymphocyte effector function by fibroblasts derived from immunoprivileged cornea (mouse), 2194
regulatory T cells enhance retinal graft survival (mouse), 5112
role of ST2 in Pseudomonas keratitis (mouse), 4626
RPE and CD4 T-cell interaction in T-cell anergy (mouse), 4654
angiotensin II and receptor subtypes in human retina, 3301
effect of alkylphosphocholines on intraretinal proliferation in RD (rabbit), 1305
gremlin and epithelial-to-mesenchymal transition in PVR, 4291
loss of α3(IV) collagen in activated corneal keratocytes, 627
muscarinic receptor subtypes on human cornea and conjunctiva, 2987
novel retinal and cone photoreceptor transcripts, 5388
OFF-type blue cone bipolar cell in rabbit retina, 3388
opsin expression during retinal development in salmonid fishes, 866
photoreceptor protective effect of minocycline, 412
regional differences in cystine accumulation in rat lens, 1253
role of GLYT2 in glycine uptake in lens core (rat), 5142
thrombin-induced VEGF expression in RPE cells, 2738
thrombin inhibition of intercellular Ca2+ wave propagation in corneal endothelial cells, 120
transgenic corneal neurofluorescence in mice, 1535
Immunoglobulin treatment of viral ocular infection (rabbit), 4171
advanced glycation end products in glaucoma, 1201
allergic conjunctival inflammation and allogeneic response to donor cornea, 4044
α1- and β1-adrenergic modulation of lacrimal gland function in mouse, 1504
antiangiogenic effect of somatostatin receptor 2 (mouse), 3480
APP and amyloid-β immunoreactivity in glaucomatous mouse retinas, 5085
association of fascin 2 with photoreceptor inner segment actin, 1380
axonal transport and cytoskeletal changes with elevated IOP (pig), 3632
bacterial transcytosis across conjunctival M cells (guinea pig), 2172
BMP-7 is antagonist of TGF-β2 in TM cells, 715
bone marrow–derived cells in substantia propria of conjunctiva, 4476
β-catenin and epithelial–mesenchymal transition in pathogenesis of pterygium, 1511
cell junction–related proteins in gelatinous drop-like corneal dystrophy, 1095
ceruloplasmin upregulation in glaucoma (mouse), 727
changes in pericytes and smooth muscle cells in ROP (kitten), 1368
characteristics of progenitor cells from ciliary body in mouse, rat, and human eyes, 1674
CNTF-induced cellular changes in murine RP, 1389
differential sensitivity of cones to iron-mediated oxidative damage (mouse), 438
differentiation of retinal stem cells transplanted into murine RP models, 446
effect of VEGF-A on expression of profibrotic growth factor and ECM genes in retina (rat), 4267
GM-CSF expression in herpetic stromal keratitis, 277
histogenesis of intravitreal membrane and secondary vitreous (mouse), 1923
IFN-γ modulation of dry eye–induced conjunctival epithelial squamous metaplasia (mouse), 2553
influence of thyroid hormone on lacrimal gland and ocular surface morphology (rat), 3038
inhibition of diabetic leukostasis and blood–retinal barrier breakdown (mouse), 858
intracellular phospholipases A2 in photoreceptor outer segment phagocytosis, 1401
KIF14 expression and age at retinoblastoma diagnosis, 4901
location of D-β-aspartic acid–containing proteins in human eyes, 3923
macular and peripheral expression of bestrophin, 3372
modeling behavior of uveal melanoma in mouse liver, 2967
monosomy 3 and vasculogenic mimicry in uveal melanoma, 1918
neuroprotection in juvenile rat model of light-induced retinopathy, 2311
nonproteolytically activated prorenin in retinal neovascularization (mouse), 422
pathological and electrophysiological features of canine cone–rod dystrophy, 4240
phenotype of limbal epithelial stem cells, 144
relative axial myopia in Egr-1 knockout mice, 11
retinal alterations in zebrafish laminin mutants, 2887
retinal cellular reorganization during normal aging, 2824
RPE65 essential for cone function in NRL-deficient mice, 534
substance P in pathogenesis of pterygia, 4482
surfactant proteins A and D in human tear fluid and lacrimal system, 3945
sutureless transplantation of amniotic membrane for ocular surface reconstruction, 1528
synaptic contact between melanopsin-containing RGCs and rod bipolar cells (rat), 3812
TNF-α–induced apoptosis in murine CMV retinitis, 1691
tolerance to retinal ischemia by hypoxic preconditioning (mouse), 1735
transplantable rabbit carrier-free epithelial sheets, 597
truncated rhodopsin in rod function and degeneration (moue), 2868
In vitro fertilization (IVF), effects on structural features of neonatal eyes, 5454
prevalence of early and late AMD in rural Northern India, 1007
prevalence of lens opacities in North India, 88
Indocyanine green (ICG), intracellular events in retinal glial cells exposed to BBG and, 4426
Indoleamine 2,3-dioxygenase (IDO), expression in human corneal cells, 4148
motion-detection asymmetries in esotropic and normal infants, 5523
Infantile nystagmus, adaptation to visual demand, 2089
Infantile spasms, contrast sensitivity in children with, 3610
adenovirus type 37 keratitis (mouse), 781
age-related differences in experimental S. aureus keratitis (rabbit), 5125
apoptotic response of HSV-1 in corneal epithelial cells, 789 (erratum, 1000)
bacterial infection and trachoma in The Gambia, 4440
Blue Mountains Eye Study, Chlamydia pneumoniae infection and AMD, 4007
Candida virulence in keratomycosis (mouse), 774
cholesterol treatment for pneumococcal keratitis (rabbit), 2661
corneal virulence of Candida albicans strains deficient in Tup1-regulated genes (mouse), 2535
CXCR3 effects in HSV-infected mice, 4162
θ-defensin in murine HSV-1 keratitis, 5118
flagellin pretreatment modulates corneal epithelial immune response to Pseudomonas infection, 4664
genetic variations among ocular isolates of Staphylococcus epidermidis, 3239
GM-CSF expression in herpetic stromal keratitis, 277
HSV-1–dependent apoptosis in corneal epithelial cells (rabbit), 4980
iNOS and CMV spread in retina (mouse), 285
interferon effect on retinal microcirculation in hepatitis C, 368
macrophages as determinants of ocular HSV-1 infection in immunized mice, 5605
mass treatment of trachoma and ocular Chlamydia trachomatis, 1492
modulation of CD8+ cytotoxic T lymphocyte effector function by fibroblasts derived from immunoprivileged cornea (mouse), 2194
oral immunization for Acanthamoeba keratitis (hamster), 5597
phase 3 safety comparisons for 1.0% azithromycin in polymeric mucoadhesive eye drops vs. 0.3% tobramycin eye drops for bacterial conjunctivitis, 3425
Pseudomonas keratitis in cathelicidin-deficient mice, 4498
regulation of IL-8 by S. aureus in conjunctival cells, 270
role of anti–glycoproteins D and K IgGs in herpes stromal keratitis, 2185
role of ST2 in Pseudomonas keratitis (mouse), 4626
secreted aspartyl proteinases in Candida albicans keratitis (mouse), 3559
spantide I in Pseudomonas aeruginosa keratitis (mouse), 797
surface bacterial flora in normal and dry eyes, 5616
TNF-α–induced apoptosis in murine CMV retinitis, 1691
topical immunoglobulin treatment of adenoviral ocular infection (rabbit), 4171
viral antigens in varicella zoster virus–induced uveitis, 3689
visual system vulnerability to prenatal endotoxin exposure (sheep), 472
absence of 4–1BB gene function and lacrimal gland inflammation (mouse), 4608
β-adrenergic receptors in inflammatory marker expression in Müller cells, 5276
allergic conjunctival inflammation and allogeneic response to donor cornea, 4044
angiotensin II type 1 receptor/NF-κB pathway in diabetes-induced retinal inflammation (mouse), 4342
bevacizumab inhibition of inflammatory corneal angiogenesis and lymphangiogenesis (mouse), 2545
complement factor H polymorphism, inflammatory mediators, and retinal vessel diameters, 3014
effect of inflammatory cytokines on RPE proliferation/migration, 5722
emodin suppression of ocular surface inflammatory reaction, 5013
inflammatory markers and hemostatic factors in ARM, 1983
Insulin-like growth factor (IGF)
hyperglycemia regulation of IGF-1 signaling in retinal endothelial cells, 3878
in RPE cell tractional force generation, 1892
Insulin-mediated vasoprotection, loss of (rat), 2350
Integrin, laminin regulation of α6 integrin gene expression, 3490
Intelligent Distributed Ontology Consensus System, 2278
chemokine profile and autoimmune pathology in genetic IFN-γ deficiency (mouse), 4616
effect on retinal microcirculation, 368
IFN-α and IFN-γ sensitize Tenon fibroblasts to mitomycin-C, 3655
IFN-γ modulation of dry eye–induced conjunctival epithelial squamous metaplasia (mouse), 2553
interferon gamma receptor 1 polymorphisms and atopic cataracts, 583
gene cluster polymorphisms and glaucoma in Chinese subjects, 2123
synergism of cytokine induction of MMP-3 in TM, 2634
Interleukin-4 deficient MRL/MpJ mice, dacryoadenitis in, 5624
mitomycin C upregulates chemokine expression in corneal fibroblasts, 2009
regulation by S. aureus in conjunctival cells, 270
Interleukin-10, measurement in aqueous humor in screening for primary intraocular lymphoma, 3253
Interleukin-17+ interphotoreceptor retinoid-binding protein-specific T cells in EAU (mouse), 4153
Interocular brightness differences, visual adaptation to, 935
Intraocular lens (IOL), novel in vitro model of posterior capsular opacity, 4679
Intraocular pressure (IOP). See also Glaucoma
axonal transport and cytoskeletal changes with elevated IOP (pig), 3632
chondroitin sulfate-derived disaccharide protects retinal cells from elevated IOP (rat), 1181
collagen cross-linking and IOP measurement, 5494
corneal elasticity in damping of IOP, 2540
effect of 15-keto latanoprost on IOP and aqueous humor dynamics (monkey), 4143
effect of ocular hypertension on retinal nitridergic pathway activity (rat), 2127
effects of IOP reduction on perimetric variability in glaucoma, 4557
effects of topical clonidine vs. brimonidine on choroidal blood flow and IOP during squatting, 4220
effects of topical Y-39983 on ocular tissues in rabbits and monkeys, 3216
endocannabinoids in retinal damage after high IOP-induced ischemia in rats, 2997
heritability of pathologic features in glaucoma, 3669
in vitro studies of antiglaucomatous prostaglandin analogues, 4123
IOP-dependent RCG dysfunction in glaucomatous DBA/2J mice, 4573
multifocal VEP vs. standard automated perimetry in glaucoma and ocular hypertension, 1173
omega 3 fatty acids and IOP with age (rat), 756
optic nerve head gene expression after exposure to elevated IOP in rat glaucoma model, 3161
prostaglandin FP receptors and 24-hour IOP variation in mice, 2095
real-time IOP during LASIK with mechanical microkeratome and femtosecond laser (pig), 68
regulation of choroidal blood flow during changes in, 3768
Intrinsic signal imaging, flash-induced light reflectance changes in macaque retina, 2903
Iris melanoma, T1799A BRAF mutation in, 4897
differential sensitivity of cones to iron-mediated oxidative damage (mouse), 438
ferritin H- and L-chains in fiber cell canine and human lenses, 3968
capillary degeneration in ischemia/reperfusion injury (rat), 361
endocannabinoids in retinal damage after high IOP-induced ischemia in rats, 2997
tolerance to retinal ischemia by hypoxic preconditioning (mouse), 1735
triamcinolone acetonide effects on leukocyte–endothelium interactions in ischemic retina (rat), 2831
L-732,138, antitumor actions in retinoblastoma, 2775
Lacerations, corneal, photo cross-linkable biodendrimers as ophthalmic adhesives, 2037
absence of 4–1BB gene function and lacrimal gland inflammation (mouse), 4608
α1- and β1-adrenergic modulation of lacrimal gland function in mouse, 1504
dacryoadenitis in IL-4 deficient MRL/MpJ mice, 5624
HSP47 in lacrimal gland pathology in chronic GVHD, 1079
influence of thyroid hormone on lacrimal gland and ocular surface morphology (rat), 3038
regulation of acid/base transporters in lacrimal gland ductal epithelia (rabbit), 3746
surfactant proteins A and D in human tear fluid and, 3945
essential for basement membrane integrity (zebrafish), 2483
regulation of α6 integrin gene expression, 3490
retinal alterations in zebrafish laminin mutants, 2887
Laser in situ keratomileusis (LASIK)
goblet cell density after LASIK procedures, 2570
predicting myopic regression after, 3516
real-time IOP during LASIK with mechanical microkeratome and femtosecond laser (pig), 68
laser-activated solder for sealing corneal wounds, 1038
selective RPE targeting with laser scanner (rabbit), 1782
upregulation of VEGF after retinal scatter laser photocoagulation (mouse), 5677
effect of 15-keto latanoprost on IOP and aqueous humor dynamics (monkey), 4143
in vitro studies of antiglaucomatous prostaglandin analogues, 4123
Leber congenital amaurosis
Apex microarray genotyping of patients with early-onset severe retinal dystrophy and, 5684
clinical and molecular genetics of, 4284
identifying novel mutations in juvenile RP and, 5690
mutation screening for, 5653
novel TULP1 mutation causing early onset RD or, 5160
RDH12 and RPE65 differ in disease expression, 332
Leber hereditary optic neuropathy
gender and color vision defects in asymptomatic carriers of, 2362
mutant ND4 induces optic neuropathy in mouse, 1
Lens intrinsic membrane protein-2 (Lim2), refractive defects and cataracts in mice lacking, 500
calpain 3 and age-related cataracts (mouse), 2685
connexins and epithelial cell proliferation (mouse), 5630
γD-crystallin–associated protein aggregation and lens fiber cell denucleation (mouse), 3719
degradation of C-terminal αA-crystallins in cataract, 4200
DNase IIβ in mouse lens, 5638
epithelial cell response to quercetin and DMSO, 3714
ferritin H- and L-chains in fiber cell canine and human lenses, 3968
genetic heterogeneity in microcornea-cataract, 3937
glucocorticoid receptor activation and signal transduction pathways in lens epithelial cells, 1724
homozygous CRYBB1 deletion in congenital cataract, 2208
INDEYE Feasibility Study, prevalence of lens opacities in North India, 88
in vitro generation of functional lens-like structures, 1245
interferon gamma receptor 1 polymorphisms and atopic cataracts, 583
lens cell survival in stressed capsular bag, 2701
light scattering predicted from particles in nuclear cataracts using Mie scattering theory, 303
MMP and TIMP expression in human lens cells, 4192
optomechanical response of human and monkey lenses in a lens stretcher, 3260
p53 expression and lens apoptosis after UV radiation exposure (rat), 4187
phakosin motifs in lens fiber cell, 5132
protein-bound UV filters in normal human lenses, 1718
proteolytic mechanisms underlying mitochondrial degradation in (mouse), 293
purinergic receptor–mediated regulation of lens connexin43, 4177
refractive defects and cataracts in Lim2 null mice, 500
regional differences in cystine accumulation in rat lens, 1253
retinoic acids and cataractogenesis, 2224
reversible binding of kynurenine to lens proteins, 3705
role of GLYT2 in glycine uptake in lens core (rat), 5142
spherical aberration changes after lens refilling with silicone oil (pig), 1261
Src suppression blocks posterior capsule opacification (chick), 2214
structural specializations emerging late in mouse lens fiber cell differentiation, 3269
target protein sits in fenestrations of α-crystallin, 2695
TGF-β1 repression of E-cadherin via Slug expression in, 2708
thyroxine-ameliorated oxidative stress in lens epithelial cells, 3698
transcytotic passage of albumin through lens epithelial cells, 1237
Lentiviral vectors, targeted transgene expression in retinal Müller glia using, 1844
Leukocyte function associated antigen (LFA), suppression of experimental autoimmune uveitis by anti-LFA-1α Ab (mouse), 2667
Leukostasis, inducible NOS in diabetic retinopathy (mouse), 5257
dynamic analysis of changes of anterior chamber angle with anterior segment OCT, 4116
nitric oxide in choroidal blood flow regulation during, 4215
complement factor D and photoreceptor susceptibility to light-induced damage (mouse), 5282
cone loss with impaired choroidal circulation after (rat), 1864
light threshold–controlled cone α−transducin translocation, 3350
melanopsin-dependent persistence and photopotentiation of pupillary light responses (mouse), 1268
neuroprotection in juvenile rat model of light-induced retinopathy, 2311
photoreceptor degeneration, AP-1 activation and (dog), 4907
photoreceptor protection against light damage by heme oxygenase-1 overexpression (rat), 5699
protective effect of TEMPOL derivatives against light-induced retinal damage (rat), 1900
sensitivity to light-induced damage in autosomal dominant retinal disease (mouse), 1942 (erratum, 3436)
objective measurement of backscattered light from cornea, 167
predicted from particles in nuclear cataracts using Mie scattering theory, 303
and ultrastructure of healed penetrating corneal wounds (rabbit), 157
endostatin generation by cells cultivated on amniotic membrane, 644
fate of limbal epithelial progenitor cells during ex vivo expansion, 605
hypoxia-enhanced expansion of, 3586
organ culture and Optisol-GS storage of cultured human limbal epithelial cells, 5484
phenotype of limbal epithelial stem cells, 144
in Duane’s retraction syndrome, 189
genome-wide scan of exfoliation syndrome, 4136
linkage replication of MYP12 locus in myopia, 4433
mapping of ovine microphthalmia to chromosome 23, 3506
Lipid peroxidation and RPE lysosomal dysfunction, 1342
Lipid rafts, DHA effect on retinal endothelial caveolae, 18
Lipoic acid, protective effect against acrolein toxicity in RPE cells, 339
Listing’s law, acute superior oblique palsy and (monkey), 2621
Listing’s plane shift due to semicircular canal stimulation, 2076
modeling behavior of uveal melanoma in mouse liver, 2967
molecular characteristics of liver metastases from uveal melanoma, 4890
Liwan Eye Study, slit lamp–simulated oblique flashlight test in Chinese eyes, 5459
LOC387715 polymorphism and AMD, 1128
Los Angeles Latino Eye Study, retinopathy in persons without diabetes, 4019
Low-vision rehabilitation and quality of life, 1476
Lrat gene, somatic ablation in mouse RPE, 5377
HDL transport into retina (chick), 4226
HPLC measurement of ocular carotenoid levels, 543
macular pigment and lutein supplementation in ABCA4 disease, 1319
macular pigment optical density and carotenoids in diet and serum, 571
and zeaxanthin protect photoreceptors from oxidative stress–induced apoptosis, 5168
bevacizumab inhibition of corneal angiogenesis and lymphangiogenesis (mouse), 2545
LYVE-1–positive macrophages in murine eyes, 2162
Lymphoma, primary intraocular
IL-10 measurement in aqueous humor in screening for, 3253
Th1/Th2 cytokine profile in (mouse), 3223
Lysophosphatidic acid and EGFR signaling in corneal wound healing, 636
LYVE-1–positive macrophages in murine eyes, 2162
M cells, conjunctival, bacterial transcytosis across (guinea pig), 2172
Macrophage migration inhibitory factor, role in neovascularization (mouse), 3545
chemotactic effect of CNTF on macrophages in RGC survival and axonal regeneration (rat), 4257
as determinants of ocular HSV-1 infection in immunized mice, 5605
in vivo retinal immunostaining demonstrates macrophage association with growing and regressing vessels, 4335
LYVE-1–positive macrophages in murine eyes, 2162
ethnic differences in macular pigment density and distribution, 3783
identification of 3-methoxyzeaxanthin in, 1435
macular and peripheral expression of bestrophin, 3372
macular pigment: test of acuity hypothesis, 2922
macular pigment optical density and carotenoids in diet and serum, 571
macular temporal responsiveness in normal aging and ARM, 4811
macular thickness measurements in myopia, 376
microperimetry in idiopathic macular telangiectasia, 3788
OCT of macula in congenital achromatopsia, 2249
OCT of macular structure in preterm and full-term children, 5207
suprathreshold contrast matching in maculopathy, 3419
anxiety and depression in, 1498
basal laminar deposit and membranous debris in early AMD, 968
CFH gene variants, smoking, and AMD risk in Japanese population, 5315
Chlamydia pneumoniae infection and, 4007
circulating hematopoietic stem cells in neovascular AMD, 5464
computer-based test for optimal visual acuity in, 4838
dendritic and synaptic plasticity of neurons in, 2782
estrogen receptor α gene polymorphisms associated with, 1012
genetics of pigment changes and geographic atrophy, 3005
haplotypes spanning complement factor H gene are protective against, 4277
heredity of small hard drusen in twins aged 20–46 years, 833
HPLC measurement of ocular carotenoid levels, 543
Intelligent Distributed Ontology Consensus System, 2278
LOC387715 polymorphism and, 1128
murine Ccl2/Cx3cr1 deficiency results in retinal lesions mimicking, 3827
prevalence of early and late AMD in rural Northern India, 1007
pseudophakia and neovascular AMD, 1472
public health impact of neovascular AMD treatments, 96
reproducibility of quantitative OCT in, 4300
and retinal protein modification by 4-hydroxy-2-nonenal, 3469
scavenger receptors for oxidized lipoprotein in, 1801
SOD2 knockdown mouse model of early AMD, 4407
suppression of choroidal neovascularization by ACE inhibition (mouse), 2321
synergies of VEGF inhibition and PDT in, 1767
visual loss and visual hallucinations in, 1416
chloride channel activity of bestrophin mutants causing, 4694
eccentric fixation assessed by Tübingen perimetry, 5815
homozygosity for novel ABCA4 founder splicing mutation associated with, 4308
macular pigment and lutein supplementation in ABCA4 disease, 1319
blood–retinal barrier permeability, retinal thickness, retinal vessel diameter and progression of, 3983
OCT vs. stereoscopic fundus photography or biomicroscopy for diagnosis of, 4963
posture and diurnal variation in, 3318
Macular expression profiling, novel retinal and cone photoreceptor transcripts, 5388
Macular oscillatory potentials, preservation in RP, 3312
Macular pigment and lutein supplementation in ABCA4 disease, 1319
ERG photostress test in evaluation of retinal function in, 2806
inflammatory markers and hemostatic factors in, 1983
macular temporal responsiveness in normal aging and, 4811
in vivo imaging of RPE mosaic in diseased retina, 2297
Magnetic resonance imaging (MRI)
assessment of drug delivery to posterior segment (rabbit), 808
in Duane-radial ray syndrome, 5505
evidence of orbital dysinnervation in Duane’s retraction syndrome, 194
of choroidal melanoma xenografts (rat), 963
in experimental ROP (rat), 4733
impaired apparent ion demand in experimental diabetic retinopathy (rat), 4753
of intraretinal ion demand in ocular injury (rat), 3796
of oculomotor nerve in congenital fibrosis of EOMs and congenital oculomotor palsy, 1601
residual visual function after loss of both cerebral hemispheres in infancy, 3098
sideslip of medial rectus muscle during vertical eye rotation, 4527
and sonography of retrobulbar human optic nerve, 1913
strabismus with axial high myopia, 1132
Manual dexterity and reading speed with hand-held magnifier, 4368
Matrix metalloproteinases (MMPs)
actin cytoskeletal integrity and MMP-2 activation in TM cells, 2105
endostatin generation by MMP and cathepsin from limbal epithelial cells on amniotic membrane, 644
Endothelin-1–mediated signaling in expression of MMPs and TIMPs in astrocytes, 3737
enhanced transscleral permeability with, 752
manipulation of MMPs to reduce retinal neovascularization in oxygen-induced retinopathy (rat), 907
MMP-14 and TIMP-2 overexpression protects against oxidant injury in RPE, 5662
MMP and TIMP expression in human lens cells, 4192
PAF and repressor effect of Sp1 in expression of MMP-9 in corneal epithelial cells, 1931
positive feedback regulation between MMP-9 and VEGF in RPE cells, 4360
synergism of cytokine induction of MMP-3 in TM, 2634
Mean ocular perfusion pressure, circadian fluctuations as risk factor for normal-tension glaucoma, 104
antiangiogenic effects of bisphosphonates (mouse), 5716
atorvastatin inhibition of choroidal neovascularization (mouse), 1839
bevacizumab inhibition of corneal angiogenesis and lymphangiogenesis (mouse), 2545
bimatoprost, prostamide activity, and conventional drainage, 4107
bortezomib-induced apoptosis in human retinoblastoma cell lines, 4706
cannabinoid receptors and bimatoprost-induced contractions of ciliary muscle, 3677
clearance of intravitreal voriconazole (rabbit), 2238
coated microneedles for drug delivery, 4038
cytotoxicity of triamcinolone acetonide on RPE cells, 2792
effect of 15-keto latanoprost on IOP and aqueous humor dynamics (monkey), 4143
effect of topical diclofenac on choroidal blood flow in postoperative pseudophakias, 5647
effects of intravitreous bevacizumab on neovascularization (rabbit), 5708
effects of pentoxifylline and alprostadil on ocular hemodynamics, 815
effects of topical clonidine vs. brimonidine on choroidal blood flow and IOP during squatting, 4220
episcleral cyclosporine implant for keratoplasty rejection, 2023
in vitro studies of antiglaucomatous prostaglandin analogues, 4123
interferon effect on retinal microcirculation, 368
mitomycin C upregulates chemokine expression in corneal fibroblasts, 2009
MRI assessment of drug delivery to posterior segment (rabbit), 808
pharmacokinetics of periocular injections, 2230
photoreceptor protective effect of minocycline, 412
retinal penetration of bevacizumab after intravitreal injection (monkey), 2814
retinal toxicity of intravitreal triamcinolone acetonide (rabbit), 390
simvastatin-induced dilation of porcine retinal arterioles, 825
slow-releasing tranilast in PTFE/PLGA after strabismus surgery (rabbit), 699
suppression of choroidal neovascularization by ACE inhibition (mouse), 2321
triamcinolone acetonide effects on leukocyte–endothelium interactions in ischemic retina (rat), 2831
triamcinolone acetonide-mediated oxidative injury, compared with dexamethasone, 5742
valsartan amelioration of retinal dysfunction in diabetic rats, 927
Meibomian gland, fatty acids in secretions of, 34
MEK1, role in 15(S)-HETE–induced angiogenesis, 4930
Melanocortin 1 receptor, expression in uveal melanoma, 1219
APITD1 expression and, 4919
BMP-7 inhibits growth of, 4882
direct-infection model of early hepatic metastasis, 4399
epigenetic inactivation of RASSF1a in, 486
manganese-enhanced MRI of choroidal melanoma xenografts (rat), 963
melanocortin 1 receptor expression in, 1219
molecular characteristics of liver metastases from, 4890
monosomy 3 and vasculogenic mimicry in, 1918
promoter methylation status of multiple genes in, 4403
T1799A BRAF mutation in iris melanoma, 4897
Melanopsin-containing RGCs, synaptic contact between rod bipolar cells and (rat), 3812
Melanopsin-dependent persistence and photopotentiation of pupillary responses (mouse), 1268
Memantine, effects in diabetic retinopathy (rat), 5152
Mental effort and independent mobility in glaucoma, 3988
Apex microarray genotyping of patients with Leber congenital amaurosis and early-onset severe retinal dystrophy, 5684
assessment of central retinal function in advanced RP, 1312
automated segmentation of optic disc from stereo color photographs, 1665
computer-based test for optimal visual acuity in AMD, 4838
decreasing visual field test–retest variability in glaucoma, 1627
diagnostic accuracy of confocal scanning laser ophthalmoscopy in glaucoma, 214
dynamic analysis of dark–light changes of anterior chamber angle with anterior segment OCT, 4116
eccentric fixation in Stargardt’s disease assessed by Tübingen perimetry, 5815
ERG photostress test in evaluation of retinal function in ARM, 2806
evaluation of retinal status using chromatic pupil light reflex activity (dog), 5178
glaucoma detection with dichoptic multifocal VEPs, 4590
Heidelberg Retina Tomograph of optic disc and RNFL in Singapore children, 4939
HPLC measurement of ocular carotenoid levels, 543
imaging comparison of optic disc and RNFL in glaucoma detection, 2644
intrinsic signal imaging in macaque retina, 2903
light scattering predicted from particles in nuclear cataracts using Mie scattering theory, 303
Liwan Eye Study, slit lamp–simulated oblique flashlight test in Chinese eyes, 5459
measurement of ocular surface irritation with Ocular Comfort Index, 4451
microperimetry in idiopathic macular telangiectasia, 3788
multiplex bead analysis of vitreous humor, 2203
new tools for evaluation of toxic ocular surface changes in rat, 5473
nondestructive quantification of analyte diffusion using OCT (rabbit), 2726
novel spatial filter to monitor glaucomatous visual field progression, 251
OCT vs. stereoscopic fundus photography or biomicroscopy for diagnosing diabetic macular edema, 4963
optic disc evaluation by OCT in nonarteritic anterior ischemic optic neuropathy, 4087
optic disc measurements in myopia with OCT and confocal scanning laser ophthalmoscopy, 3178
optical imaging of retina activated by suprachoroidal-transretinal stimulation (cat), 4777
pachymetric mapping with Visante anterior segment-OCT, 5499
panretinal, high-resolution color photography of mouse fundus, 2769
pattern ERG monitoring of RGC dysfunction in murine glaucoma, 745
predicting myopic regression after LASIK, 3516
quantitative subanalysis of OCT data, 839
relationship between visual field sensitivity and RNFL thickness measured by OCT, 258
repeatability of confocal scanning laser ophthalmoscopy, SLP, and OCT in glaucoma, 1156
repeatability of Humphrey perimetry in RP patients, 4720
reproducibility of anterior chamber angle measurements by OCT, 3683
reproducibility of endothelial assessment, 2062
reproducibility of quantitative OCT in neovascular AMD, 4300
screening and diagnosis of optic pathway gliomas in children using VEPs, 2895
sensitivity of temporal artery biopsy, 675
simultaneous fundus imaging and OCT in mouse retina, 1283
SLP and OCT in normal and glaucomatous eyes, 2099
spatial frequency selectivity of human motion system revealed by masking, 3897
spatial luminance contrast sensitivity measured with transient VEP, 3396
spectral-domain OCT for 3D retinal imaging of rodent retina, 1808
topographic angiography in classic and occult choroidal neovascularization, 1751
two semiautomated methods for evaluating endothelial cells of eye bank corneas, 3077
validation study of VEP Vernier acuity in adults, 4070
validity and repeatability of new test for aniseikonia, 58
visual field clustering with machine learning classifiers, 5582
3-Methoxyzeaxanthin in macula, 1435
Micro RNA expression (miRNA)
in human and rat retinas, 3962
Apex microarray genotyping of patients with Leber congenital amaurosis and early-onset severe retinal dystrophy, 5684
comparison of gene expression in human conjunctiva and cornea, 2050
identifying novel mutations in Leber congenital amaurosis and juvenile RP, 5690
molecular characteristics of liver metastases from uveal melanoma, 4890
novel retinal and cone photoreceptor transcripts, 5388
of RPE cells exposed to REF-1/TFPI-2, 516
vitreous modulation of gene expression in RPE cells, 1853
Microperimetry in idiopathic macular telangiectasia, 3788
Microphthalmia, linkage mapping to chromosome 23 (sheep), 3506
Mie scattering theory, light scattering predicted from particles in nuclear cataracts using, 303
Minocycline, photoreceptor protective effect of, 412
mitochondrial fission in differentiated RGC-5 cells, 2145
nuclear and mitochondrial analysis of primary angle-closure glaucoma, 5591
oxidative damage and diabetic retinopathy (mouse), 3805
protective effect of lipoic acid against acrolein-induced toxicity and mitochondrial dysfunction in RPE cells, 339
proteolytic mechanisms underlying degradation in lens (mouse), 293
suppression of mitochondrial oxidative stress in optic neuritis (mouse), 681
Mitogen-activated protein kinases (MAPKs), and NF-κB in photoreceptor apoptosis, 4766
IFN-α and IFN-γ sensitize Tenon fibroblasts to, 3655
upregulation of chemokine expression in corneal fibroblasts, 2009
Mitosis defect, induced by Pax6 p46 overexpression, 5408
Monocyte chemoattractant protein-1, mitomycin C upregulates chemokine expression in corneal fibroblasts, 2009
Monosomy 3 and vasculogenic mimicry in uveal melanoma, 1918
Monte Carlo simulation of visual field progression in glaucoma, 1642
Motion-sensitivity loss in glaucoma, 2913
among older drivers, visual impairment and, 1483
functions of MUC16 in corneal epithelial cells, 4509
ocular surface: challenge to enable and protect vision (Friedenwald Lecture), 4391
β-adrenergic receptors in inflammatory marker expression in, 5276
targeted transgene expression in retinal Müller glia using lentiviral vectors, 1844
transcriptome of Müller cells and two spontaneous cell lines, 5229
two spontaneous human Müller cell lines from diabetic donors, 874
Multifocal spectacles and tripping in the elderly, 1466
heterogeneity of lesions in optic neuritis, 4549
visual field and RNFL measurements in, 5798
Multiplex bead analysis of vitreous humor, 2203
Muscarinic receptor subtypes on human cornea and conjunctiva, 2987
Myasthenia gravis, autoimmune ocular, new mouse model, 5101
sodium 4-phenylbutyrate corrects myocilin misfolding, 1683
Myofibroblasts, corneal, TLR-3 and -9 in, 3069
axial length and peripheral refractive error before and after onset of, 2510
blur adaptation in emmetropia and, 2932
choroidal regulation of scleral glycosaminoglycan synthesis during recovery from induced myopia (chick), 2957
contrast sensitivity and higher-order aberrations after orthokeratology for, 550
dynamics of accommodative facility in myopes, 4375
effect on contrast thresholds, 2371
effects of foveal ablation on emmetropization and form-deprivation myopia (monkey), 3914
ethnic differences in impact of parental myopia, 2520
familial aggregation of refractive error in Old Order Amish, 4002
form-deprivation myopia in chick and retinal gene expression, 3430
genetic mapping of susceptibility loci for, 4924
glycosaminoglycan levels in tree shrew sclera during induced myopia development and recovery, 2947
linkage replication of MYP12 locus in, 4433
macular thickness measurements in, 376
myopia correction and self-reported visual functioning in Mexican children, 4949
optic disc measurements in myopia with OCT and confocal scanning laser ophthalmoscopy, 3178
parental, and myopia in COMET children, 562
parental ocular and activity history and future development of, 3524
predicting myopic regression after LASIK, 3516
relative axial myopia in Egr-1 knockout mice, 11
roles of PAX6 and SOX2 in, 4421
susceptibility of eyes of lower vertebrate to visual environment (tilapia), 4829
treatment of strabismus with axial high myopia, 1132
Myosin light chain, benzalkonium chloride–induced dephosphorylation of, 2001
MYP12 locus in myopia, 4433
Neovascularization. See also Angiogenesis
antiangiogenic effect of somatostatin receptor 2 (mouse), 3480
bevacizumab inhibition of corneal angiogenesis and lymphangiogenesis (mouse), 2545
antiangiogenic effects of bisphosphonates (mouse), 5716
atorvastatin inhibition of (mouse), 1839
PDT and apoptosis in rat model, 4741
quantitative fluorescein angiographic analysis of, 349
reduced photoreceptor damage after PDT through NOS blockade (monkey), 2268
suppression by ACE inhibition (mouse), 2321
suppression by dendritic cell vaccination targeting VEGFR2 (mouse), 4795
topographic angiography in classic and occult types, 1751
effects of intravitreous bevacizumab on (rabbit), 5708
endogenous TNFα suppression of neovascularization in corneal stroma (mouse), 3051
EPA prevents choroidal neovascularization in mice, 4328
in vivo retinal immunostaining demonstrates macrophage association with growing and regressing vessels, 4335
pseudophakia and neovascular AMD, 1472
public health impact of neovascular AMD treatments, 96
RAGE ligand upregulation of VEGF secretion in ARPE-19 cells, 1355
inhibition by calcitriol (mouse), 2327
manipulation of MMPs for reduction of, in oxygen-induced retinopathy (rat), 907
nonproteolytically activated prorenin in (mouse), 422
role of macrophage migration inhibitory factor in (mouse), 3545
suppression by EMD478761 implant, 5184
Nepafenac, corneal analgesic effects of, 182
Nerve growth factor (NGF) gene therapy improves corneal allograft survival (rat), 1043
Nerves and innervation. See also Retinal nerve fiber layer
activation of BMP canonical signaling pathway in optic nerve head, 5058
age-related decline in parasympathetic nerve fibers in submacular choroid, 479
antioxidant gene therapy in optic neuritis (mouse), 5360
axonal transport and cytoskeletal changes with elevated IOP (pig), 3632
bacterial DNA confers neuroprotection after optic nerve injury (mouse and rat), 3441
corneal innervation and cellular changes after corneal transplantation, 621
corneal innervation and sensitivity in patients with dry eye, 173
effect of transcorneal electrical stimulation in acute-phase optic nerve injury (rat), 2356
effects of nepafenac on corneal sensory nerve fibers, 182
EphB2 and ephrin-B2 upregulation at optic nerve head in glaucomatous mice with axon loss, 5567
ERG findings in dominant optic atrophy with OPA1 mutations, 820
gender and color vision defects in asymptomatic carriers of Leber’s hereditary optic neuropathy, 2362
gene expression in experimental glaucoma and optic nerve transection (rat), 5539
heterogeneity of lesions in optic neuritis, 4549
improved conduction velocity after optic neuritis, 692
impulse activity in corneal sensory nerve fibers after PRK, 4032
innervation of tissue-engineered corneal implants (pig), 3537
MRI evidence of orbital dysinnervation in Duane’s retraction syndrome, 194
MRI in Duane-radial ray syndrome, 5505
mutant ND4-induced optic neuropathy (mouse), 1
oculomotor nerve in congenital fibrosis of EOMs and congenital oculomotor palsy, 1601
optic disc evaluation by OCT in nonarteritic anterior ischemic optic neuropathy, 4087
optic nerve head gene expression after exposure to elevated IOP in rat glaucoma model, 3161
optic nerve head in Myocilin glaucoma, 238
population differences in elastin maturation in optic nerve head and astrocytes, 3209
predictors of relative afferent pupillary defect in optic neuropathy, 3616
prenatal endotoxin exposure and optic nerve myelination (sheep), 472
RNFL thinning in autosomal dominant optic atrophy with OPA1 mutations, 4079
SIRT1 neuroprotection in experimental optic neuritis (mouse), 3602
sonography and MRI of retrobulbar human optic nerve, 1913
suppression of mitochondrial oxidative stress in optic neuritis (mouse), 681
3-D histomorphometry of early glaucomatous monkey optic nerve head, 5068
3-D histomorphometry of normal and early glaucomatous monkey optic nerve head, 3195, 4597
transgenic analysis of rodent anterior ischemic optic neuropathy–induced RGC stress and loss (mouse), 2304
transgenic corneal neurofluorescence in mice, 1535
Neural reprogramming in retinal degeneration (mouse), 3364
Neurofibromatosis, screening and diagnosis of optic pathway gliomas in children with, 2895
Neurokinin-1 receptor antagonist, antitumor actions in retinoblastoma, 2775
Neuromuscular junctions, density and distribution in normal and botulinum toxin–treated EOMs (rabbit and monkey), 3594
dendritic and synaptic plasticity of neurons in AMD, 2782
histone deacetylase and neuronal differentiation, 2845
retinal cellular reorganization during normal aging, 2824
Neuroprotection. See also Protective effects
bacterial DNA confers neuroprotection after optic nerve injury (mouse and rat), 3441
BDNF in retinal protection against light damage–mediated stress (mouse), 2877
effect of transcorneal electrical stimulation in acute-phase optic nerve injury (rat), 2356
in juvenile rat model of light-induced retinopathy, 2311
SIRT1 neuroprotection in experimental optic neuritis (mouse), 3602
Neuroprotection D1, in homeostatic regulation of photoreceptor cell integrity (Proctor Lecture), 4866
BDNF in retinal protection against light damage–mediated stress (mouse), 2877
cellular changes in murine RP induced by CNTF, 1389
chemotactic effect of CNTF on macrophages in RGC survival and axonal regeneration (rat), 4257
minimizing renal toxicity of verteporfin PDT (rat), 430
neuroprotection in juvenile rat model of light-induced retinopathy, 2311
in rat conjunctival goblet cells, 1543
Ret activation does not protect from light-induced damage (mouse), 5199
CD18 integrins and neutrophil–keratocyte interactions during corneal wound healing (mouse), 5023
GM-CSF expression in herpetic stromal keratitis, 277
electronic medical records system for clinical research and the EMR–EDC interface, 4383
testing of intraocular drugs for clinical use, 4861
Nicotine, attenuation of endotoxin-induced uveitis (rat), 2719
in choroidal blood flow regulation during light/dark transitions, 4215
resveratrol-induced dilation of porcine retinal arterioles, 4232
Nitric oxide synthase (NOS)
effect of ocular hypertension on retinal nitridergic pathway activity (rat), 2127
inducible NOS in diabetic retinopathy (mouse), 5257
iNOS and CMV spread in retina (mouse), 285
reduced photoreceptor damage after PDT through NOS blockade (monkey), 2268
Nonarteritic anterior ischemic optic neuropathy (NAION), optic disc evaluation by OCT in, 4087
Nonsteroidal anti-inflammatory drugs
corneal analgesic effects of nepafenac, 182
effect of topical diclofenac on choroidal blood flow in postoperative pseudophakias, 5647
Norrie disease, gene mutations in Japanese patients with familial exudative vitreoretinopathy and, 1276
Notch signaling in corneal epithelial cell differentiation and proliferation, 3576
Nuclear factor-κB (NF-κB)
angiotensin II type 1 receptor/NF-κB pathway in diabetes-induced retinal inflammation (mouse), 4342
and HSV-1–dependent apoptosis in corneal epithelial cells (rabbit), 4980
lactate causes NF-κB activation and CD44 shedding in cultured TM cells, 1615
and MAPKs in photoreceptor apoptosis, 4766
infantile, acuity development in, 4093
infantile nystagmus adapts to visual demand, 2089
optokinetic, in severely visually impaired patients, 4542
Ocular Comfort Index, measurement of ocular surface irritation with, 4451
Ocular dominance, laterality, and refraction in Singaporean children, 3533
Ocular hypertension. See also Glaucoma; Intraocular pressure
effect on retinal nitridergic pathway activity (rat), 2127
multifocal VEP vs. standard automated perimetry in glaucoma and, 1173
Ocular Response Analyzer, biomechanical properties of cornea, 3026
challenge to enable and protect vision (Friedenwald Lecture), 4391
emodin suppression of inflammatory reaction of, 5013
measurement of ocular surface irritation with Ocular Comfort Index, 4451
new tools for evaluation of toxic ocular surface changes in rat, 5473
surface bacterial flora in normal and dry eyes, 5616
sutureless transplantation of amniotic membrane for reconstruction of, 1528
Ocular torsion due to semicircular canal stimulation, 2076
Oculomotor control in premature children, 2595
Oculomotor nerve, in congenital fibrosis of EOMs and congenital oculomotor palsy, 1601
OFF-type blue cone bipolar cell in rabbit retina, 3388
Omega 3 fatty acids and IOP with age (rat), 756
ERG findings in dominant optic atrophy with mutations of, 820
RNFL thinning in autosomal dominant optic atrophy with mutations of, 4079
Opsin, expression during retinal development in salmonid fishes, 866
ERG findings in dominant optic atrophy with OPA1 mutations, 820
RNFL thinning in autosomal dominant optic atrophy with OPA1 mutations, 4079
automated segmentation from stereo color photographs, 1665
cortical organization and optic disc damage in glaucoma, 733
effect of disc size and disease severity on diagnostic accuracy of Heidelberg Retina Tomograph Glaucoma Probability Score, 2653
evaluation by OCT in nonarteritic anterior ischemic optic neuropathy, 4087
Heidelberg Retina Tomograph of optic disc and RNFL in Singapore children, 4939
heritability of pathologic features in glaucoma, 3669
imaging comparison of optic disc and RNFL in glaucoma detection, 2644
measurements in myopia with OCT and confocal scanning laser ophthalmoscopy, 3178
relation of retinal vessel caliber to optic disc and cup diameters, 63
relationship of retinal vascular caliber with optic disc diameter in children, 4945
Optic flow deficits in amblyopia, second-order, 5532
activation of BMP canonical signaling pathway in optic nerve head, 5058
antioxidant gene therapy in optic neuritis (mouse), 5360
bacterial DNA confers neuroprotection after optic nerve injury (mouse and rat), 3441
connective tissue structure of tree shrew optic nerve, 2134
effect of transcorneal electrical stimulation in acute-phase optic nerve injury (rat), 2356
EphB2 and ephrin-B2 upregulation at optic nerve head in glaucomatous mice with axon loss, 5567
gender and color vision defects in asymptomatic carriers of Leber’s hereditary optic neuropathy, 2362
gene expression in experimental glaucoma and optic nerve transection (rat), 5539
heterogeneity of lesions in optic neuritis, 4549
improved conduction velocity after optic neuritis, 692
MRI evidence of orbital dysinnervation in Duane’s retraction syndrome, 194
mutant ND4-induced optic neuropathy in mouse, 1
optic disc evaluation by OCT in nonarteritic anterior ischemic optic neuropathy, 4087
optic nerve head gene expression after exposure to elevated IOP in rat glaucoma model, 3161
optic nerve head in Myocilin glaucoma, 238
population differences in elastin maturation in optic nerve head and astrocytes, 3209
predictors of relative afferent pupillary defect in optic neuropathy, 3616
prenatal endotoxin exposure and optic nerve myelination (sheep), 472
SIRT1 neuroprotection in experimental optic neuritis (mouse), 3602
sonography and MRI of retrobulbar human optic nerve, 1913
suppression of mitochondrial oxidative stress in optic neuritis (mouse), 681
3-D histomorphometry of normal and early glaucomatous monkey optic nerve head, 3195, 4597
transgenic analysis of rodent anterior ischemic optic neuropathy–induced RGC stress and loss (mouse), 2304
Optical coherence tomography (OCT)
of birefringent properties of keratoconus corneas, 3551
cellular and functional OCT of human retina (Cogan Lecture), 5340
dynamic analysis of dark–light changes of anterior chamber angle with anterior segment OCT, 4116
effect of blinking on tear dynamics, 3032
and Heidelberg retinal tomography parameters in detecting early and moderate glaucoma, 3138
and histology of RNFL thickness in glaucoma (monkey), 3645
inner retinal abnormalities in X-linked RP with RPGR mutations, 4759
of macula in congenital achromatopsia, 2249
of macular structure in preterm and full-term children, 5207
microperimetry in idiopathic macular telangiectasia, 3788
in multiple sclerosis, 5773
nondestructive quantification of analyte diffusion (rabbit), 2726
optic disc evaluation by OCT in nonarteritic anterior ischemic optic neuropathy, 4087
optic disc measurements in myopia with OCT and confocal scanning laser ophthalmoscopy, 3178
pachymetric mapping with Visante anterior segment-OCT, 5499
peripapillary nerve fiber layer thickness profile with, 3154
quantitative subanalysis of OCT data, 839
RDH12 and RPE65 differ in disease expression, 332
relationship between RNFL and perimetry measurements (monkey), 763
relationship between visual field sensitivity and RNFL thickness, 258
repeatability in glaucoma, 1156
reproducibility of anterior chamber angle measurements with, 3683
reproducibility of quantitative OCT in neovascular AMD, 4300
retinal abnormalities in early Alzheimer’s disease, 2285
RNFL defects in RP patients, 4748
RNFL thickness after acute primary angle closure measured with, 1659
rule extraction for glaucoma detection with, 244
simultaneous fundus imaging and OCT in mouse retina, 1283
and SLP in normal and glaucomatous eyes, 2099
spectral-domain OCT for 3D retinal imaging of rodent retina, 1808
vs. stereoscopic fundus photography or biomicroscopy for diagnosing diabetic macular edema, 4963
Stratus OCT in preperimetric glaucoma, 1635
structure vs. function in glaucoma, 3662
Optical imaging of retina activated by suprachoroidal-transretinal stimulation (cat), 4777
Optineurin mutant induces death of RGCs, 1607
Ornithine cytotoxicity in RPE cells, 464
Orthokeratology, contrast sensitivity and higher-order aberrations after, 550
Oscillatory potentials of dark-adapted ERG in ROP (rat), 5788
Outflow, omega 3 fatty acids and IOP with age (rat), 756
AMD and retinal protein modification by 4-hydroxy-2-nonenal, 3469
bilberry anthocyanins in defense against, 2343
and blink-suppressed dry eye (rat), 1552
cytotoxicity evaluation of different vegetable oil vectors, 5000
differential sensitivity of cones to iron-mediated oxidative damage (mouse), 438
in hydrostatic pressure–induced RGC damage, 4580
lens epithelial cell response to quercetin and DMSO, 3714
lutein and zeaxanthin protect photoreceptors from apoptosis induced by, 5168
mechanisms of immune system activation in glaucoma, 705
mitochondrial, suppression in optic neuritis (mouse), 681
mitochondrial oxidative damage and diabetic retinopathy (mouse), 3805
MMP-14 and TIMP-2 overexpression protects against oxidant injury in RPE, 5662
photoreceptor protective effect of minocycline against, 412
protective effect of lipoic acid against acrolein toxicity in RPE cells, 339
retina in vitamin E–deficient αTTP null mice, 396
SOD2 knockdown mouse model of early AMD, 4407
thyroxine-ameliorated, in lens epithelial cells, 3698
triamcinolone acetonide-mediated oxidative injury, compared with dexamethasone, 5742
Oxidized lipoprotein in AMD, scavenger receptors for, 1801
effect of acute hypoxia and hyperoxia on multifocal ERG, 3405
effect of hyperoxia in detached feline retina, 1335
retinal oxygen metabolism in retinal artery occlusion (rat), 2290
Oxygen-induced retinopathy
aquaporin-1–independent microvessel proliferation in mouse model of, 4802
genetics and susceptibility to (rat), 1761
manipulation of MMPs to reduce retinal neovascularization in (rat), 907
riluzole inhibits retinal hemorrhage in (rat), 5671
P2X7 cell death receptor activation, cytotoxicity evaluation of different vegetable oil vectors, 5000
p38 MAP kinase pathway and stromelysin regulation in trabecular meshwork cells, 3126
p53 expression and lens apoptosis after UV radiation exposure (rat), 4187
Pachymetric mapping with Visante anterior segment-OCT, 5499
Paclitaxel, in murine retinoblastoma model, 3437
Parental ocular and activity history and future myopia, 3524
expression in pigeon retina, 2503
Pax6 p46 overexpression induces mitosis defect, 5408
required for postnatal eye development (mouse), 3292
acuity development in infantile nystagmus, 4093
anterior capsular plaque in congenital cataract, 4209
astigmatism in 12-year-old Australian children, 73
axial length and peripheral refractive error before and after onset of myopia, 2510
biometry of Caucasian and African-American cataractous pediatric eyes, 4671
British Infantile and Childhood Glaucoma Eye Study, 4100
children unable to perform screening tests in Vision in Preschoolers Study, 83
composition of infant vs. adult human corneal basement membranes, 4989
contrast sensitivity in children with infantile spasms, 3610
contribution of oculometric parameters to refraction by age and ethnicity, 4846
cost-effectiveness of cycloplegic agents in Nigerian children, 1025
effects of IVF on structural features of neonatal eyes, 5454
ethnic differences in impact of parental myopia, 2520
Heidelberg Retina Tomograph of optic disc and RNFL in Singapore children, 4939
identifying novel mutations in Leber congenital amaurosis and juvenile RP, 5690
immaturities limiting infant binocular stereopsis, 1424
infants’ accommodation responses to dynamic stimuli, 949
KIF14 expression and age at retinoblastoma diagnosis, 4901
modeling dose-response in children with amblyopia, 2589
motion-detection asymmetries in esotropic and normal infants, 5523
myopia correction and self-reported visual functioning in Mexican children, 4949
OCT of macular structure in preterm and full-term children, 5207
ocular dominance, laterality, and refraction in Singaporean children, 3533
oculomotor control in premature children, 2595
optical factors and resolution acuity in children with Down syndrome, 3995
parental myopia and progression of myopia in COMET children, 562
parental ocular and activity history and future myopia, 3524
perceptual learning and recovery of visual acuity in juvenile amblyopia, 5046
progression of esotropia in infancy, 661
relationship of retinal vascular caliber with optic disc diameter in children, 4945
residual visual function after loss of both cerebral hemispheres in infancy, 3098
retinal vascular caliber and children’s ethnicity, gender, and birth parameters, 1018
scotopic visual thresholds in ROP, 4854
screening and diagnosis of optic pathway gliomas in, 2895
screening and treating amblyopia, 2084
strabismus detection in preschool vision screening, 3115
Penetrating keratoplasty (corneal transplantation)
corneal innervation and cellular changes after, 621
episcleral cyclosporine implant for keratoplasty rejection, 2023
photo cross-linkable biodendrimers as ophthalmic adhesives for, 2037
(+)Pentazocine, prevention of excitotoxicity in RGCs by, 4785
Pentoxifylline, effects on ocular hemodynamics, 815
Perceptual learning and recovery of visual acuity in juvenile amblyopia, 5046
Pericytes, and smooth muscle cells in ROP (kitten), 1368
of central retinal function in advanced RP, 1312
eccentric fixation in Stargardt’s disease assessed by Tübingen perimetry, 5815
effects of IOP reduction on perimetric variability in glaucoma, 4557
frequency doubling, quantifying adaptation and fatigue effects in, 943
microperimetry in idiopathic macular telangiectasia, 3788
multifocal VEP vs. standard automated perimetry in ocular hypertension and glaucoma, 1173
relationship between RNFL and measurements of (monkey), 763
repeatability of Humphrey perimetry in RP patients, 4720
structure vs. function in glaucoma, 3662
visual field clustering with machine learning classifiers, 5582
Peripapillary atrophy, inheritance of, 2529
Peripherin/rds function, intramembrane determinant of (mouse), 2975
Persistent hyperplastic primary vitreous, due to somatic mosaic deletion of Arf (mouse), 491
Phakosin motifs in lens fiber cell, 5132
bimatoprost, prostamide activity, and conventional drainage, 4107
episcleral cyclosporine implant for keratoplasty rejection, 2023
of periocular injections, 2230
Pharmacy claims data to study glaucoma medication adherence, 5052
Phospholipases A2, intracellular, in photoreceptor outer segment phagocytosis, 1401
Photo cross-linkable biodendrimers as ophthalmic adhesives, 2037
Photodynamic therapy (PDT)
and apoptosis in rat choroidal neovascularization model, 4741
focal macular ERG and angiographic findings after, 2254
neurotrophic factors minimize renal toxicity of verteporfin PDT (rat), 430
reduced photoreceptor damage after PDT through NOS blockade (monkey), 2268
synergies of VEGF inhibition and PDT in AMD, 1767
AAV-mediated expression targeting of rods and cones with human rhodopsin kinase promoter (mouse), 3954
acetylcholinesterase in photoreceptor death after photic stress (rat), 1290
association of fascin 2 with photoreceptor inner segment actin, 1380
cellular response to photoreceptor death in murine RD, 849
circadian control of tyrosine phosphorylation of cGMP-gated ion channels in (chick), 901
in CNGB3 achromatopsia, 3864
complement factor D and photoreceptor susceptibility to light-induced damage (mouse), 5282
cone loss with impaired choroidal circulation after light exposure (rat), 1864
differential sensitivity of cones to iron-mediated oxidative damage (mouse), 438
endoplasmic reticulum stress activation in degenerating photoreceptors (mouse), 5191
function of visual arrestins in rod photoreceptors (mouse), 1968
GDNF stimulation of rods and dopaminergic amacrine cells (chick), 5306
gene expression analysis of photoreceptor cell loss in Bbs4-knockout mice, 3329
genetic ablation of cone photoreceptors and retinal fold elimination in rd7 mouse, 2799
glial contributions to retinal detachment–induced photoreceptor degeneration (mouse), 2760
homeostatic regulation of photoreceptor cell integrity (Proctor Lecture), 4866
interaction between Tubby-like protein 1 and dynamin-1 (mouse), 2837
intracellular phospholipases A2 in outer segment phagocytosis, 1401
intramembrane determinant of peripherin/rds function for photoreceptor disk morphogenesis (mouse), 2975
late-onset cone degeneration induced by Rds mutation and gene rescue (mouse), 5397
light exposure, photoreceptor degeneration, and AP-1 activation (dog), 4907
light-induced apoptosis, 40
light threshold–controlled cone α−transducin translocation, 3350
lutein and zeaxanthin protect photoreceptors from oxidative stress–induced apoptosis, 5168
multifocal ERG patterns of cone degeneration in RP, 383
NF-κB and MAPKs in photoreceptor apoptosis, 4766
novel retinal and cone photoreceptor transcripts, 5388
OFF-type blue cone bipolar cell in rabbit retina, 3388
pathological and electrophysiological features of canine cone–rod dystrophy, 4240
protection against light damage by heme oxygenase-1 overexpression (rat), 5699
reduced photoreceptor damage after PDT through NOS blockade (monkey), 2268
Ret activation does not protect from light-induced damage (mouse), 5199
rod function predicts blood vessel abnormality in ROP (rat), 4351
RPE65 essential for cone function in NRL-deficient mice, 534
synaptic contact between melanopsin-containing RGCs and rod bipolar cells (rat), 3812
transcorneal electrical stimulation protection of (rat), 4725
truncated rhodopsin in rod function and degeneration (moue), 2868
Wnt signaling during photoreceptor degeneration, 5733
zebrafish cone photoreceptor–specific promoter and genetic rescue of achromatopsia, 522
Photorefractive keratectomy (PRK)
impulse activity in corneal sensory nerve fibers after, 4032
optical zone decentration and aberrations after (cat), 5806
PHSRN peptide, stimulation of epithelial cell migration by, 1110
ethnic differences in macular pigment density and distribution, 3783
genetics of pigment changes and geographic atrophy, 3005
macular pigment: test of acuity hypothesis, 2922
macular pigment optical density in the elderly, 1458
ocular hypopigmentation in Rab38cht/cht mice, 3905
coated microneedles for drug delivery, 4038
pharmacologically manipulated accommodative dynamics (monkey), 323
Pioglitazone, modulation of cholesterol homeostasis by antiproliferative drugs in pterygium fibroblasts, 3450
PITX2 gene, genotype-phenotype correlations in Axenfeld-Rieger malformation and glaucoma with FOXC1 and PITX2 mutations, 228
Plasminogen activators cause death of RGCs, 1884
Platelet-activating factor (PAF), and repressor effect of Sp1 in expression of MMP-9 in corneal epithelial cells, 1931
Platelet-derived growth factor (PDGF)-C, in PVR, 2335
Plus disease, changes in pericytes and smooth muscle cells in ROP (kitten), 1368
Pneumatic retinopexy, gas jets in (pig), 2734
Pneumococcal keratitis, cholesterol treatment for (rabbit), 2661
Polytetrafluoroethylene/polylactide-co-glycolide (PTFE/PLGA), slow-releasing tranilast in PTFE/PLGA after strabismus surgery (rabbit), 699
Posterior capsular opacification
blocked by Src suppression (chick), 2214
lens cell survival in stressed capsular bag, 2701
novel in vitro model of, 4679
Posture and diurnal variation in diabetic macular edema, 3318
Potassium ion channels, resveratrol-induced dilation of porcine retinal arterioles, 4232
Prehension deficits in amblyopia, 1139
Primary angle closure, OCT measurement of RNFL thickness after, 1659
homeostatic regulation of photoreceptor cell integrity, 4866
Nicolas G. Bazan, 2007 recipient of Proctor Medal, 4864
Progenitor cells from ciliary body in mouse, rat, and human eyes, 1674
Projeto Glaucoma, glaucoma prevalence in South Brazilian population, 4974
Proliferative vitreoretinopathy (PVR)
gremlin and epithelial-to-mesenchymal transition in, 4291
in vivo retinal tolerance of heavy silicone oils (rabbit), 1873
Prostaglandin FP receptors and 24-hour IOP variation in mice, 2095
functional assessment of subretinal prosthetic (rat), 916
innervation of tissue-engineered corneal implants (pig), 3537
bacterial DNA confers neuroprotection after optic nerve injury (mouse and rat), 3441
of basic FGF-impregnated nanoparticles in RCS rats, 3381
of caffeine against UV-induced apoptosis in corneal epithelial cells, 652
chemotactic effect of CNTF on macrophages in RGC survival and axonal regeneration (rat), 4257
chondroitin sulfate-derived disaccharide protects retinal cells from elevated IOP (rat), 1181
of erythropoietin on RGCs in glaucoma mice, 1212
glutathione effect on binding of kynurenine to lens proteins, 3705
haplotypes spanning complement factor H gene are protective against AMD, 4277
impaired cytoprotective mechanisms in eyes with pseudoexfoliation syndrome/glaucoma, 5558
of lipoic acid against acrolein toxicity in RPE cells, 339
lipopeptide vaccines to prevent ocular herpes infection, 4643
lutein and zeaxanthin protect photoreceptors from oxidative stress–induced apoptosis, 5168
of minocycline on photoreceptors, 412
MMP-14 and TIMP-2 overexpression protects against oxidant injury in RPE, 5662
neuroprotection in juvenile rat model of light-induced retinopathy, 2311
photoreceptor protection against light damage by heme oxygenase-1 overexpression (rat), 5699
prevention of excitotoxicity in RGCs by (+)pentazocine, 4785
SIRT1 neuroprotection in experimental optic neuritis (mouse), 3602
suppression of mitochondrial oxidative stress in optic neuritis (mouse), 681
of TEMPOL derivatives against light-induced retinal damage (rat), 1900
transcorneal electrical stimulation protection of photoreceptors (rat), 4725
of uridine on cornea in rabbit dry eye model, 1102
Protein-bound UV filters in normal human lenses, 1718
Proteolytic mechanisms underlying mitochondrial degradation in lens (mouse), 293
AMD and retinal protein modification by 4-hydroxy-2-nonenal, 3469
analysis of exfoliation deposits, 1447
analysis of RPE cells exposed to REF-1/TFPI-2, 516
location of D-β-aspartic acid–containing proteins in human eyes, 3923
Prothrombin, corneal activation to form thrombin, 134
Proton-coupled electrogenic folate transporter in retina, 5299
PRPF31 mutations, in autosomal dominant RP, 1330
Pseudoexfoliation syndrome/glaucoma, impaired cytoprotective mechanisms in eyes with, 5558
Pseudomonas aeruginosa keratitis
in cathelicidin-deficient mice, 4498
flagellin pretreatment modulates corneal epithelial immune response to, 4664
role of ST2 in (mouse), 4626
spantide I in (mouse), 797
Pseudophakia and neovascular AMD, 1472
Pseudoxanthoma elasticum with generalized retinal dysfunction, 4250
β-catenin and epithelial–mesenchymal transition in pathogenesis of, 1511
modulation of cholesterol homeostasis by antiproliferative drugs in fibroblasts, 3450
prognosis-determinant candidate genes in, 3566
substance P in pathogenesis of, 4482
Public health impact of neovascular AMD treatments, 96
evaluation of retinal status using chromatic pupil light reflex activity (dog), 5178
melanopsin-dependent persistence and photopotentiation of (mouse), 1268
pupil size and retinal straylight, 2375
Purinergic receptor–mediated regulation of lens connexin43, 4177
Rab38 gene, ocular hypopigmentation in Rab38cht/cht mice, 3905
attitudes of African-Americans about eye examinations, 1989
biometry of Caucasian and African-American cataractous pediatric eyes, 4671
contribution of oculometric parameters to refraction by age and ethnicity, 4846
ethnic differences in impact of parental myopia, 2520
ethnic differences in macular pigment density and distribution, 3783
Los Angeles Latino Eye Study, retinopathy in persons without diabetes, 4019
population differences in elastin maturation in optic nerve head and astrocytes, 3209
retinal vascular caliber and children’s ethnicity, gender, and birth parameters, 1018
Radiation therapy, for retinoblastoma, mechanism of tumor cell death after chemotherapy, radiation, and vascular targeting therapy (mouse), 5371
RAGE ligand, upregulation of VEGF secretion in ARPE-19 cells, 1355
RASSF1a gene, epigenetic inactivation in uveal melanoma, 486
phenotype of retinal degeneration in persons with mutations of, 1824
and RPE65 differ in disease expression, 332
Reading speed with hand-held magnifier, 4368
fascicular specialization in (human and monkey), 3089
horizontal rectus muscle anatomy in strabismic monkeys, 2576
sideslip of medial rectus muscle during vertical eye rotation, 4527
REF-1/TFPI-2, analysis of RPE cells exposed to, 516
contribution of oculometric parameters to refraction by age and ethnicity, 4846
ocular dominance, laterality, and refraction in Singaporean children, 3533
simultaneous defocus integration during refractive development (chick), 5352
axial length and peripheral refractive error before and after onset of myopia, 2510
blur adaptation in emmetropia and myopia, 2932
and cataracts in Lim2 null mice, 500
choroidal regulation of scleral glycosaminoglycan synthesis during recovery from induced myopia (chick), 2957
contrast sensitivity and higher-order aberrations after orthokeratology for myopia, 550
dynamics of accommodative facility in myopes, 4375
effect of myopia on contrast thresholds, 2371
effects of foveal ablation on emmetropization and form-deprivation myopia (monkey), 3914
ethnic differences in impact of parental myopia, 2520
familial aggregation in Old Order Amish, 4002
form-deprivation myopia in chick and retinal gene expression, 3430
genetic mapping of myopia susceptibility loci, 4924
Heidelberg Retina Tomograph of optic disc and RNFL in Singapore children, 4939
levels in tree shrew sclera during induced myopia development and recovery, 2947
linkage replication of MYP12 locus in myopia, 4433
macular thickness measurements in myopia, 376
myopia correction and self-reported visual functioning in Mexican children, 4949
optic disc measurements in myopia with OCT and confocal scanning laser ophthalmoscopy, 3178
parental myopia and progression of myopia in COMET children, 562
parental ocular and activity history and future myopia, 3524
relative axial myopia in Egr-1 knockout mice, 11
roles of PAX6 and SOX2 in myopia, 4421
Shihpai Eye Study, correctable visual impairment in elderly Taiwanese, 1032
and strabismus detection in preschool vision screening, 3115
temporal constraints on experimental emmetropization in infant monkeys, 957
treatment of strabismus with axial high myopia, 1132
functional optical zone of cornea, 1053
goblet cell density after LASIK procedures, 2570
impulse activity in corneal sensory nerve fibers after PRK, 4032
optical zone decentration and aberrations after PRK (cat), 5806
predicting myopic regression after LASIK, 3516
wound healing after corneal femtosecond laser keratotomy (rabbit), 2068
Relative afferent pupillary defect, brightness sensitivity and color perception as predictors of, 3616
Repetitive transcranial magnetic stimulation, bidirectional modulation of primary visual cortex excitability, 5782
Resveratrol-induced dilation of porcine retinal arterioles, 4232
Ret activation does not protect from light-induced damage (mouse), 5199
blood–retinal barrier permeability, retinal thickness, retinal vessel diameter and progression of diabetic macular edema, 3983
HDL transport of lutein into (chick), 4226
miRNA expression in human and rat retinas, 3962
pseudoxanthoma elasticum with generalized retinal dysfunction, 4250
quail retinal carotenoids, 3976
retinal hemorrhage in oxygen-induced retinopathy, riluzole inhibition of (rat), 5671
retinal straylight and pupil size, 2375
retinopathy in persons without diabetes, 4019
Retinal degeneration (RD)
caspase activation by 7-ketocholesterol in retinal neurosensory cells, 1362
caspase-dependent apoptosis in (rat), 2753
cellular response to photoreceptor death in (mouse), 849
CERKL mutation in autosomal recessive RD among Yemenite Jews, 5431
genetic determinant on mouse chromosome 6, 405
in GNPTAB deficiency (mouse), 5221
inherited, high-resolution imaging with adaptive optics in, 3283
late-onset cone degeneration induced by Rds mutation and gene rescue (mouse), 5397
macular pigment and lutein supplementation in ABCA4 disease, 1319
neural reprogramming in (mouse), 3364
novel form of transducin-dependent RD (mouse), 5445
novel TULP1 mutation causing Leber congenital amaurosis or early onset RD, 5160
phenotype in persons with RDH12 mutations, 1824
VEGF in retinal progenitor cell proliferation in (mouse), 4315
N-cadherin expression in retinal detachment and reattachment (rat), 1832
controlling RPE injury after (mouse), 1348
effect of alkylphosphocholines on intraretinal proliferation in (rabbit), 1305
glial contributions to retinal detachment–induced photoreceptor degeneration (mouse), 2760
hyperoxia and oxygen consumption in detached feline retina, 1335
in vivo retinal tolerance of heavy silicone oils (rabbit), 1873
Retinal ganglion cells (RGCs)
calpains in RGC death, 5420
CaMKIIαB mediates survival response in, 3854
chemotactic effect of CNTF on macrophages in RGC survival and axonal regeneration (rat), 4257
differentiation of retinal stem cells transplanted into murine RP models, 446
double-stranded RNA-dependent protein kinase in ER stress–induced retinal neuron damage, 3729
IOP-dependent RCG dysfunction in glaucomatous DBA/2J mice, 4573
mitochondrial fission in differentiated RGC-5 cells, 2145
neuroprotective effect of erythropoietin on RGCs in glaucoma mice, 1212
optineurin mutant induces death of, 1607
oxidative stress in hydrostatic pressure–induced RGC damage, 4580
pattern ERG monitoring of RGC dysfunction in murine glaucoma, 745
plasminogen activators cause death of, 1884
prevention of excitotoxicity in RGCs by (+)pentazocine, 4785
progressive dysfunction in DBA/2J mouse model of glaucoma, 4564
retinal phenotypes in mammalian ciliary body after injury of (mouse), 5266
synaptic contact between melanopsin-containing RGCs and rod bipolar cells (rat), 3812
transgenic analysis of rodent anterior ischemic optic neuropathy–induced RGC stress and loss (mouse), 2304
Retinal nerve fiber layer (RNFL)
defects identified by Stratus OCT in preperimetric glaucoma, 1635
defects in RP patients, 4748
Heidelberg Retina Tomograph of optic disc and RNFL in Singapore children, 4939
heritability of pathologic features in glaucoma, 3669
imaging comparison of optic disc and RNFL in glaucoma detection, 2644
OCT and histology of RNFL thickness in glaucoma (monkey), 3645
peripapillary nerve fiber layer thickness profile with OCT, 3154
relationship between visual field sensitivity and RNFL thickness measured by OCT, 258
relationship with perimetry measurements and (monkey), 763
stronger structure–function relationship with enhanced corneal compensation than with variable corneal compensation in SLP, 1651 (erratum, 1917)
structure vs. function in glaucoma, 3662
thickness after acute primary angle closure measured with OCT, 1659
thinning in autosomal dominant optic atrophy with OPA1 mutations, 4079
visual field and RNFL measurements in multiple sclerosis, 5798
Retinal pigment epithelium (RPE)
analysis of cells exposed to REF-1/TFPI-2, 516
Bcl-xL in survival of, 3846
c-Met and EGFR in RPE wound healing, 2242
caspase-8–mediated apoptosis in, 3341
controlling RPE injury after experimental retinal detachment (mouse), 1348
cytotoxicity of triamcinolone acetonide on, 2792
effect of inflammatory cytokines on RPE proliferation/migration, 5722
endogenous bone marrow–derived cells express RPE cell markers, 4321
gene expression profiling of zebrafish embryonic RPE, 881
glypican 4, bactericidal/permeability-increasing protein in, 5750
homeostatic regulation of photoreceptor cell integrity (Proctor Lecture), 4866
IGF in RPE cell tractional force generation, 1892
in vivo imaging of RPE mosaic in diseased retina, 2297
JAM-A in corneal endothelium and, 3928
lipid peroxidation and RPE lysosomal dysfunction, 1342
MMP-14 and TIMP-2 overexpression protects against oxidant injury in, 5662
ornithine cytotoxicity in, 464
positive feedback regulation between MMP-9 and VEGF in, 4360
posterior pole injury and peripheral RPE proliferation (pig), 355
protective effect of lipoic acid against acrolein toxicity in, 339
rapid recruitment of TIP47 in (mouse), 2858
RPE and CD4 T-cell interaction in T-cell anergy (mouse), 4654
selective RPE targeting with laser scanner (rabbit), 1782
somatic ablation of Lrat gene in mouse RPE, 5377
spermine cytotoxicity in, 455
thrombin-induced VEGF expression in, 2738
TRPC channels mediate basal calcium entry in RPE cells, 5767
vitreous modulation of gene expression in, 1853
Retinal scatter laser photocoagulation, upregulation of VEGF after (mouse), 5677
age, blood pressure and, 557
alternatives to arteriole to venule ratio in measurement of, 52
blood pressure and retinal arteriole diameter, 328
children’s ethnicity, gender, birth parameters and, 1018
complement factor H polymorphism, inflammatory mediators, and retinal vessel diameters, 3014
progression of diabetic macular edema, 3983
relation to optic disc and cup diameters, 63
relationship with optic disc diameter in children, 4945
carbonic anhydrase inhibitor–induced relaxation of porcine retinal arterioles, 4688
G6PD in retinal vein occlusion, 2747
HGF in retinal angiogenesis, 1793
hyperhomocysteinemia and low methionine stress as risk factors for central retinal venous occlusion, 1441
in vivo retinal immunostaining demonstrates macrophage association with growing and regressing vessels, 4335
interferon effect on retinal microcirculation, 368
loss of insulin-mediated vasoprotection (rat), 2350
resveratrol-induced dilation of porcine retinal arterioles, 4232
retinal oxygen metabolism in retinal artery occlusion (rat), 2290
retinal vascular network geometry and cognitive ability in elderly population, 1995
simvastatin-induced dilation of porcine retinal arterioles, 825
vascular reactivity in diabetic retinopathy, 1744
Retinitis pigmentosa (RP)
ABCA4 mutations in severe retinopathies in Spanish patients, 985
central retinal function in advanced RP, 1312
CNTF-induced cellular changes in (mouse), 1389
differentiation of retinal stem cells transplanted into murine RP models, 446
disease course of patients with X-linked RP due to RPGR mutations, 1298
identifying novel mutations in Leber congenital amaurosis and juvenile RP, 5690
inner retinal abnormalities in X-linked RP with RPGR mutations, 4759
multifocal ERG patterns of cone degeneration in, 383
novel mutation in carbonic anhydrase IV gene that causes RP, 3459
population study of X-linked RP, 4012
preservation of macular oscillatory potentials in, 3312
PRPF31 mutations in autosomal dominant RP, 1330
repeatability of Humphrey perimetry in patients with, 4720
restoration of visual responses in aged dystrophic rats after channelopsin-2 gene transfer, 3821
Ret activation does not protect from light-induced damage (mouse), 5199
RNFL defects in patients with, 4748
antitumor action of neurokinin-1 receptor antagonist, 2775
bortezomib-induced apoptosis in human retinoblastoma cell lines, 4706
KIF14 expression and age at diagnosis of, 4901
mechanism of tumor cell death after chemotherapy, radiation, and vascular targeting therapy (mouse), 5371
paclitaxel treatment in murine model, 3437
topotecan vitreous levels after periocular or intravenous delivery (rabbit), 3761
tumor vessel maturation (mouse), 2476
Retinoic acids, in cataractogenesis, 2224
Retinopathy of prematurity (ROP)
changes in pericytes and smooth muscle cells in kitten model of, 1368
high-resolution manganese-enhanced MRI of experimental ROP (rat), 4733
oscillatory potentials of dark-adapted ERG in (rat), 5788
rod function predicts blood vessel abnormality in (rat), 4351
scotopic visual thresholds in, 4854
expression profiling of retinoschisin-deficient retina in postnatal mouse development, 891
gene therapy in Rs1h-KO mouse, 3837
RS1 mutants associated with X-linked retinoschisis, 2491
Rho-associated protein kinase inhibitor, antiscarring effects of Y-27632 in glaucoma filtration surgery (rabbit), 5549
light exposure, photoreceptor degeneration, and AP-1 activation (dog), 4907
novel form of transducin-dependent RD (mouse), 5445
sensitivity to light-induced damage in autosomal dominant retinal disease (mouse), 1942 (erratum, 3436)
truncated rhodopsin in rod function and degeneration (moue), 2868
AAV-mediated expression targeting of rods and cones with human rhodopsin kinase promoter (mouse), 3954
signaling in Tenon’s capsule fibroblasts, 2152
Riboflavin-UVA–induced collagen cross-linking and IOP measurement, 5494
Riluzole, inhibition of retinal hemorrhage in oxygen-induced retinopathy (rat), 5671
RLBP1 gene promotor, identification of, 3872
microRNAs expressed in mouse eye, 509
miRNA expression in human and rat retinas, 3962
RNA-dependent protein kinase in ER stress–induced retinal neuron damage, 3729
Rotterdam Study, complement factor H polymorphism, inflammatory mediators, and retinal vessel diameters, 3014
essential for cone function in NRL-deficient mice, 534
and RDH12 differ in disease expression, 332
disease course of patients with X-linked RP due to, 1298
inner retinal abnormalities in X-linked RP with, 4759
RTEF-1, novel alternatively spliced isoforms in endothelial cells and murine retina, 3775
coated microneedles for drug delivery, 4038
preclinical safety evaluation of intravitreal VEGF antibody injection (rabbit), 1773
risk of falls and motor vehicle collisions in glaucoma, 1149
visual field loss and risk of falls in older adults, 4445
visual impairment and motor vehicle crashes among older drivers, 1483
Sarcoidosis, HSP-70/Hom gene polymorphisms and uveitis in patients with, 3019
Scanning laser polarimetry (SLP)
effect of atypical birefringence patterns on glaucoma detection using SLP with variable corneal compensation, 223
with enhanced corneal compensation, for glaucoma detection, 3146
and OCT in normal and glaucomatous eyes, 2099
repeatability in glaucoma, 1156
stronger structure–function relationship with enhanced corneal compensation than with variable corneal compensation in, 1651 (erratum, 1917)
Scavenger receptors for oxidized lipoprotein in AMD, 1801
Schnyder crystalline corneal dystrophy, UBIAD1 mutations in, 5007
Schwann cell transplantation preserves vision without immunosuppression (rat), 1906
choroidal regulation of scleral glycosaminoglycan synthesis during recovery from induced myopia (chick), 2957
levels in tree shrew sclera during induced myopia development and recovery, 2947
MMP enhancement of transscleral permeability, 752
Scotopic visual thresholds in ROP, 4854
Second-harmonic imaging microscopy of corneas, 1087
Shihpai Eye Study, correctable visual impairment in elderly Taiwanese, 1032
activation of BMP canonical signaling pathway, 5058
cyclic ADP-ribose–dependent calcium signaling pathway in bovine rod outer segments, 978
endothelin-1–mediated signaling in expression of MMPs and TIMPs in astrocytes, 3737
glucocorticoid receptor activation and signal transduction pathways in lens epithelial cells, 1724
lysophosphatidic acid and EGFR signaling in corneal wound healing, 636
notch signaling in corneal epithelial cell differentiation and proliferation, 3576
p38 MAP kinase pathway and stromelysin regulation in trabecular meshwork cells, 3126
regulation of IL-8 by S. aureus in conjunctival cells, 270
Rho-kinase signaling in Tenon’s capsule fibroblasts, 2152
Src suppression blocks posterior capsule opacification (chick), 2214
upregulation of TGF-β–induced tissue transglutaminase in subconjunctival fibroblasts, 1952
Wnt signaling during photoreceptor degeneration, 5733
Simvastatin-induced dilation of porcine retinal arterioles, 825
SIRT1 neuroprotection in experimental optic neuritis (mouse), 3602
dacryoadenitis in IL-4 deficient MRL/MpJ mice, 5624
in vivo confocal study of cornea in, 2017
Slit lamp–simulated oblique flashlight test in Chinese eyes, 5459
Slug, TGF-β1 repression of E-cadherin via Slug expression in lens epithelium, 2708
SMCT1 and SMCT2 expression in retina, 3356
Smoking, CFH gene variants, and AMD risk in Japanese population, 5315
Smooth muscle cells, and pericytes in ROP (kitten), 1368
SOD2 knockdown mouse model of early AMD, 4407
Sodium 4-phenylbutyrate corrects myocilin misfolding in glaucoma, 1683
Sodium-coupled monocarboxylate transporter expression in retina, 3356
Somatostatin receptor 2, antiangiogenic effect (mouse), 3480
SOX2, role in myopia, 4421
laminin regulation of α6 integrin gene expression by altering level of Sp1 and Sp3, 3490
PAF and repressor effect of Sp1 in expression of MMP-9 in corneal epithelial cells, 1931
Spantide I, in Pseudomonas aeruginosa keratitis (mouse), 797
Spatial frequency selectivity of human motion system, 3897
Spectacles, multifocal, and tripping in the elderly, 1466
Spermine cytotoxicity in RPE cells, 455
Src suppression blocks posterior capsule opacification (chick), 2214
ST2, role in Pseudomonas keratitis (mouse), 4626
age-related differences in experimental S. aureus keratitis (rabbit), 5125
genetic variations among ocular isolates of S. epidermidis, 3239
regulation of IL-8 by S. aureus in conjunctival cells, 270
eccentric fixation assessed by Tübingen perimetry, 5815
homozygosity for novel ABCA4 founder splicing mutation associated with, 4308
macular pigment and lutein supplementation in ABCA4 disease, 1319
atorvastatin inhibition of choroidal neovascularization (mouse), 1839
simvastatin-induced dilation of porcine retinal arterioles, 825
circulating hematopoietic stem cells in neovascular AMD, 5464
differentiation of retinal stem cells transplanted into murine RP models, 446
fate during ex vivo expansion, 605
secretion of cornea-like tissue in vitro by, 5038
acute superior oblique palsy
change in static eye alignment in (monkey), 2602
changes in dynamic properties during vertical saccades (monkey), 2612
relationship to Listing’s law (monkey), 2621
with axial high myopia, 1132
binocular summation of contrast in strabismic amblyopia, 5332
cross-axis eye movements in primates with A pattern strabismus, 665
detection in preschool vision screening, 3115
horizontal rectus muscle anatomy in strabismic monkeys, 2576
horizontal saccade disconjugacy in strabismic monkeys, 3107
oculomotor nerve in congenital fibrosis of EOMs and congenital oculomotor palsy, 1601
slow-releasing tranilast in PTFE/PLGA after strabismus surgery (rabbit), 699
Streptococcus pneumoniae, cholesterol treatment for pneumococcal keratitis (rabbit), 2661
Stromelysin, p38 MAP kinase pathway and stromelysin regulation in trabecular meshwork cells, 3126
Subretinal prosthetic, functional assessment of (rat), 916
Substance P, in pathogenesis of pterygia, 4482
Superior oblique palsy, acute
change in static eye alignment in (monkey), 2602
changes in dynamic properties during vertical saccades (monkey), 2612
relationship to Listing’s law (monkey), 2621
Superoxide dismutase, mitochondrial oxidative damage and diabetic retinopathy (mouse), 3805
Suprachoroidal-transretinal stimulation, optical imaging of retina activated by (cat), 4777
Suprathreshold contrast matching in maculopathy, 3419
Surfactant proteins A and D, in human tear fluid and lacrimal system, 3945
Sydney Myopia Study, contribution of oculometric parameters to refraction by age and ethnicity, 4846
CD8 regulatory T cells in experimental autoimmune uveitis (mouse), 2178
expression of Th-1 chemokines and receptors in mouse model of dry eye, 2561
IL-17+ interphotoreceptor retinoid-binding protein-specific T cells in EAU (mouse), 4153
modulation of CD8+ cytotoxic T lymphocyte effector function by fibroblasts derived from immunoprivileged cornea (mouse), 2194
regulatory T cells enhance retinal graft survival (mouse), 5112
RPE and CD4 T-cell interaction in T-cell anergy (mouse), 4654
viral antigens recognized by T cells in varicella zoster virus–induced uveitis, 3689
TACSTD2 mutations, in gelatinous drop-like corneal dystrophy, 4490
decompression-induced ocular tear film bubbles, 3756
effect of blinking on tear dynamics, 3032
fatty acids in meibomian gland secretions, 34
ocular surface: challenge to enable and protect vision (Friedenwald Lecture), 4391
surfactant proteins A and D in human tear fluid and lacrimal system, 3945
trypsin inhibitory capacity in vernal keratoconjunctivitis, 264
Technology, electronic medical records system for clinical research and the EMR–EDC interface (new developments), 4383
Temporal artery biopsy, sensitivity of, 675
Tenon’s capsule fibroblasts
IFN-α and IFN-γ sensitize fibroblasts to mitomycin-C, 3655
Rho-kinase signaling in, 2152
The Gambia, bacterial infection and trachoma in, 4440
corneal prothrombin activation to form, 134
inhibition of intercellular Ca2+ wave propagation in corneal endothelial cells by, 120
thrombin-induced VEGF expression in RPE cells, 2738
Thymosin β-4, antiapoptotic effects on corneal epithelial cells, 27
influence on lacrimal gland and ocular surface morphology (rat), 3038
thyroxine-ameliorated oxidative stress in lens epithelial cells, 3698
TIP47, rapid recruitment in RPE (mouse), 2858
innervation of tissue-engineered corneal implants (pig), 3537
transplantable rabbit carrier-free epithelial sheets, 597
Tissue inhibitors of matrix metalloproteinase (TIMPs)
endothelin-1–mediated signaling in expression of MMPs and TIMPs in astrocytes, 3737
MMP-14 and TIMP-2 overexpression protects against oxidant injury in RPE, 5662
MMP and TIMP expression in human lens cells, 4192
Tissue transglutaminase, expression in subconjunctival fibroblasts, 1952
Tobramycin, phase 3 safety comparisons for 1.0% azithromycin in polymeric mucoadhesive eye drops vs. 0.3% tobramycin eye drops for bacterial conjunctivitis, 3425
Toll-like receptors (TLRs)
in acute anterior uveitis, 1711
TLR-3 and -9 in human corneal myofibroblasts, 3069
Topographic angiography, in classic and occult choroidal neovascularization, 1751
influence of eyelid morphology on corneal shape, 112
3-D atlas of corneal shape, 1072
Topotecan, vitreous levels after periocular or intravenous delivery for retinoblastoma (rabbit), 3761
actin cytoskeletal integrity and MMP-2 activation in, 2105
BMP-7 is antagonist of TGF-β2 in, 715
ECM gene alternative splicing by TM cells in response to mechanical stretching, 1164
effects of TGF-β2, BMP-4, and gremlin in, 1191
elevated alkaline phosphatase in glaucomatous TM, 3184
lactate causes NF-κB activation and CD44 shedding in cultured TM cells, 1615
p38 MAP kinase pathway and stromelysin regulation in, 3126
synergism of cytokine induction of MMP-3 in, 2634
and bacterial infection in The Gambia, 4440
mass treatment of ocular Chlamydia trachomatis and, 1492
Tranilast, slow-releasing tranilast in PTFE/PLGA after strabismus surgery (rabbit), 699
Transcorneal electrical stimulation
effect in acute-phase optic nerve injury (rat), 2356
protection of photoreceptors by (rat), 4725
Transcranial direct current stimulation, bidirectional modulation of primary visual cortex excitability, 5782
light threshold–controlled cone α−transducin translocation, 3350
transducin-dependent RD (mouse), 5445
Transforming growth factor-β (TGF-β)
BMP-7 is antagonist of TGF-β2 in TM cells, 715
effects of TGF-β2, BMP-4, and gremlin in TM, 1191
inhibition of corneal epithelial TGF-β2 production by extracellular matrix, 1061
repression of E-cadherin via Slug expression in lens epithelium, 2708
upregulation of TGF-β–induced tissue transglutaminase in subconjunctival fibroblasts, 1952
Transient receptor potential (TRP) channels, TRPC channels mediate basal calcium entry in RPE cells, 5767
amniotic membrane, sutureless, for ocular surface reconstruction, 1528
allergic conjunctival inflammation and allogeneic response to donor cornea, 4044
CCR1 deletion prolongs allograft survival (mouse), 1228
corneal innervation and cellular changes after, 621
episcleral cyclosporine implant for keratoplasty rejection, 2023
NGF gene therapy improves allograft survival (rat), 1043
photo cross-linkable biodendrimers as ophthalmic adhesives for, 2037
cultivated corneal endothelial cell sheet transplantation (monkey), 4519
regulatory T cells enhance retinal graft survival (mouse), 5112
Schwann cell transplantation preserves vision without immunosuppression (rat), 1906
transplantable rabbit carrier-free epithelial sheets, 597
Trauma, ocular, manganese-enhanced MRI studies of intraretinal ion demand in (rat), 3796
Travoprost, in vitro studies of antiglaucomatous prostaglandin analogues, 4123
Treatment adherence, pharmacy claims data to study glaucoma medication adherence, 5052
cytotoxicity on RPE cells, 2792
effects on leukocyte–endothelium interactions in ischemic retina (rat), 2831
intravitreal, retinal toxicity of (rabbit), 390
oxidative injury mediated by, compared with dexamethasone, 5742
Trypsin, inhibitory capacity in vernal keratoconjunctivitis, 264
Tubby-like protein 1, interaction with dynamin-1 (mouse), 2837
Tübingen perimetry, eccentric fixation in Stargardt’s disease assessed by, 5815
TULP1 mutation causing Leber congenital amaurosis or early onset RD, 5160
Tumor necrosis factor-α (TNF-α)
apoptosis in murine CMV retinitis induced by, 1691
endogenous TNF-α suppression of neovascularization in corneal stroma (mouse), 3051
role of soluble TNF receptors for TNF-α in uveitis, 3246
synergism of cytokine induction of MMP-3 in TM, 2634
primary intraocular lymphoma
IL-10 measurement in aqueous humor in screening for, 3253
Th1/Th2 cytokine profile (mouse), 3223
antitumor action of neurokinin-1 receptor antagonist, 2775
bortezomib-induced apoptosis in human retinoblastoma cell lines, 4706
KIF14 expression and age at diagnosis of, 4901
mechanism of tumor cell death after chemotherapy, radiation, and vascular targeting therapy (mouse), 5371
paclitaxel treatment in murine model, 3437
topotecan vitreous levels after periocular or intravenous delivery (rabbit), 3761
tumor vessel maturation (mouse), 2476
screening and diagnosis of optic pathway gliomas in children, 2895
APITD1 expression and, 4919
BMP-7 inhibits growth of, 4882
direct-infection model of early hepatic metastasis, 4399
epigenetic inactivation of RASSF1a in, 486
manganese-enhanced MRI of choroidal melanoma xenografts (rat), 963
melanocortin 1 receptor expression in, 1219
modeling behavior of, in mouse liver, 2967
molecular characteristics of liver metastases from, 4890
monosomy 3 and vasculogenic mimicry in, 1918
promoter methylation status of multiple genes in, 4403
T1799A BRAF mutation in iris melanoma, 4897
heredity of small hard drusen in twins aged 20–46 years, 833
heritable features of optic disc, 2469
inheritance of peripapillary atrophy, 2529
lipopeptide vaccines to prevent ocular herpes infection, 4643
macrophages as determinants of ocular HSV-1 infection in immunized mice, 5605
oral immunization for Acanthamoeba keratitis (hamster), 5597
suppression of choroidal neovascularization by dendritic cell vaccination targeting VEGFR2 (mouse), 4795
Valsartan, amelioration of retinal dysfunction in diabetic rats, 927
Varicella zoster virus–induced uveitis, viral antigens in, 3689
Vascular endothelial growth factor (VEGF)
antiangiogenic effect of somatostatin receptor 2 (mouse), 3480
effect of VEGF-A on expression of profibrotic growth factor and ECM genes in retina (rat), 4267
endogenous TNFα suppression of neovascularization in corneal stroma (mouse), 3051
memantine effects in diabetic retinopathy (rat), 5152
positive feedback regulation between MMP-9 and VEGF in RPE cells, 4360
preclinical safety evaluation of intravitreal VEGF antibody injection (rabbit), 1773
RAGE ligand upregulation of VEGF secretion in ARPE-19 cells, 1355
in retinal progenitor cell proliferation in murine retinal degeneration, 4315
synergies of VEGF inhibition and PDT in AMD, 1767
thrombin-induced VEGF expression in RPE cells, 2738
upregulation after retinal scatter laser photocoagulation (mouse), 5677
Vascular endothelial growth factor receptor 2 (VEGFR2), suppression of choroidal neovascularization by dendritic cell vaccination targeting (mouse), 4795
Vasculature. See also Endothelial cells; Neovascularization
age, blood pressure, and retinal vessel diameter, 557
alternatives to arteriole to venule ratio in measuring retinal vascular caliber, 52
aquaporin-1–independent microvessel proliferation in murine oxygen-induced retinopathy, 4802
bevacizumab inhibition of corneal angiogenesis and lymphangiogenesis (mouse), 2545
blood pressure and retinal arteriole diameter, 328
blood–retinal barrier permeability, retinal thickness, retinal vessel diameter and progression of diabetic macular edema, 3983
capillary degeneration in ischemia/reperfusion injury (rat), 361
carbonic anhydrase inhibitor–induced relaxation of porcine retinal arterioles, 4688
complement factor H polymorphism, inflammatory mediators, and retinal vessel diameters, 3014
G6PD in retinal vein occlusion, 2747
HGF in retinal angiogenesis, 1793
hyperhomocysteinemia and low methionine stress as risk factors for central retinal venous occlusion, 1441
inhibition of angiogenesis by intraceptor nanoparticles (mouse), 2030
in vivo retinal immunostaining demonstrates macrophage association with growing and regressing vessels, 4335
interferon effect on retinal microcirculation, 368
loss of insulin-mediated vasoprotection (rat), 2350
relation of retinal vessel caliber to optic disc and cup diameters, 63
relationship of retinal vascular caliber with optic disc diameter in children, 4945
resveratrol-induced dilation of porcine retinal arterioles, 4232
retinal oxygen metabolism in retinal artery occlusion (rat), 2290
retinal vascular caliber and children’s ethnicity, gender, and birth parameters, 1018
retinal vascular network geometry and cognitive ability in elderly population, 1995
rod function predicts blood vessel abnormality in ROP (rat), 4351
sensitivity of temporal artery biopsy, 675
simvastatin-induced dilation of porcine retinal arterioles, 825
vascular reactivity in diabetic retinopathy, 1744
Vasoactive intestinal peptide (VIP), downregulation of endotoxin-induced uveitis by intravitreal VIP encapsulated in liposomes (rat), 3230
Vegetable oil vectors, cytotoxicity evaluation of, 5000
Vernal keratoconjunctivitis, trypsin inhibitory capacity in, 264
Verteporfin PDT, neurotrophic factors minimize renal toxicity of (rat), 430
Vestibulo-ocular reflex, initial misdirection, 5512
attitudes of African-Americans about eye examinations, 1989
children unable to perform screening tests in Vision in Preschoolers Study, 83
screening and treating amblyopia, 2084
strabismus detection in preschool children, 3115
visual acuity measurement in Chinese reading population, 2383
acuity development in infantile nystagmus, 4093
computer-based test for optimal visual acuity in AMD, 4838
macular pigment: test of acuity hypothesis, 2922
measurement in Chinese reading population, 2383
myopia correction and self-reported visual functioning in Mexican children, 4949
optical factors and resolution acuity in children with Down syndrome, 3995
perceptual learning and recovery of visual acuity in juvenile amblyopia, 5046
public health impact of neovascular AMD treatments, 96
Rasch analysis of Daily Living Tasks Dependent on Vision, 1976
screening and treating amblyopia, 2084
Visual adaptation to interocular brightness differences, 935
bidirectional modulation of primary visual cortex excitability, 5782
defects in amblyopia, 1575
organization and optic disc damage in glaucoma, 733
retinotopic organization of primary visual cortex in glaucoma, 733
Visual evoked potentials (VEPs)
abnormal waveform of human pattern VEP: gamma oscillatory components, 4534
effect of transcorneal electrical stimulation in acute-phase optic nerve injury (rat), 2356
glaucoma detection with dichoptic multifocal VEPs, 4590
heterogeneity of lesions in optic neuritis, 4549
improved conduction velocity after optic neuritis, 692
motion-detection asymmetries in esotropic and normal infants, 5523
multifocal VEP vs. standard automated perimetry in ocular hypertension and glaucoma, 1173
restoration of visual responses in aged dystrophic rats after channelopsin-2 gene transfer, 3821
in screening and diagnosis of optic pathway gliomas in children, 2895
spatial luminance contrast sensitivity measured with transient VEP, 3396
validation study of VEP Vernier acuity in adults, 4070
fellow eye losses in asymmetric glaucoma, 2626
novel spatial filter to monitor glaucomatous visual field progression, 251
progression determined by Monte Carlo simulation in glaucoma, 1642
relationship between visual field sensitivity and RNFL thickness measured by OCT, 258
and risk of falls in older adults, 4445
decreasing test–retest variability in glaucoma, 1627
eccentric fixation in Stargardt’s disease assessed by Tübingen perimetry, 5815
multifocal VEP vs. standard automated perimetry in ocular hypertension and glaucoma, 1173
visual field and RNFL measurements in multiple sclerosis, 5798
visual field clustering with machine learning classifiers, 5582
accommodation in pre-presbyopes with, 3888
CNTF reduces vision in rats in dose-dependent manner, 5756
domain structure assessment of Vision Impairment Questionnaire, 1001
importance and difficulty of driving in low-vision population, 4955
low-vision rehabilitation and quality of life, 1476
optokinetic nystagmus in severely visually impaired patients, 4542
residual visual function after loss of both cerebral hemispheres in infancy, 3098
role in motor vehicle crashes among older drivers, 1483
Shihpai Eye Study, correctable visual impairment in elderly Taiwanese, 1032
and visual hallucinations in AMD, 1416
Visual masking, spatial frequency selectivity of human motion system revealed by, 3897
Visual spatial integration in elderly persons, 2940
Visual system vulnerability to prenatal endotoxin exposure (sheep), 472
Vitamin E, retina in αTTP null mice fed diet deficient in, 396
aerosol drug delivery during, 5243
polylactic acid for visualizing vitreous body during (rabbit), 3277
histogenesis of intravitreal membrane and secondary vitreous (mouse), 1923
modulation of gene expression in RPE cells, 1853
multiplex bead analysis of vitreous humor, 2203
persistent hyperplastic primary vitreous due to somatic mosaic deletion of Arf (mouse), 491
Voriconazole, intravitreal, clearance of (rabbit), 2238