After the WDT, there was no significant change in mean CT, either in all 88 patients considered together or in the OA group (
Table 2). The mean CT increase in all patients was approximately 2.5 μm, or approximately 1% of normal CT. There was, however, a significant increase in CT in the AC group (5.5 μm,
P = 0.04). CT also increased significantly among the 80 subjects whose IOP rose more than 2 mm Hg (3.2 μm,
P = 0.048). Mean ACD decreased in all patients considered together, although this decrease was not significant (mean decrease = −7 μm,
P = 0.34). A mean decrease of −18 μm in ACD was observed in the AC group, but this was of borderline significance (
P = 0.07). In pseudophakic AC patients (
n = 7), the mean decrease in ACD was even greater (−52 μm); the significance of this finding could not be reliably assessed because of the small sample size. In the OA group, a small, statistically insignificant increase in mean ACD was observed (+3 μm,
P = 0.74); pseudophakic OA patients (
n = 11) had a mean increase in ACD of +38 μm. There were significant increases in systolic, diastolic, and mean BP, as well as in IOP in the overall patient group. BP and IOP were significantly increased in each of the two major diagnostic groups as well. The increase in IOP for the three ACS patients with past LPIs was on average the same as for the rest of the AC group (6 mm Hg). Because PP includes both BP and IOP, the rise in these two parameters was parallel enough that there was no significant change in mean or diastolic PP. There was, however, a significant increase in systolic PP overall and in OA patients. The IOP increase was significantly greater in AC patients than in OA patients (6.00 versus 4.25 mm Hg,
P = 0.004). After the WDT, a significant increase in mean AL of 12 μm occurred in the overall group, and mean AL increased significantly in both OA (9 μm,
P = 0.01) and AC groups (16 μm,
P < 0.0001) separately (
Table 2).