MMP-1 | Basal MMP-1 expression in the TM | Human and bovine TM cell culture, human TM explant culture, human corneoscleral explant culture | 11, 14 |
| MMP-1 expression is decreased in the TM after exposure to corticosteroids | Human TM culture | 52 |
MMP-2 | Basal MMP-2 expression in the TM | Human and bovine TM cell culture, human TM explant culture, human corneoscleral explant culture | 11, 14 |
| Punctuate MMP-2 immunostaining pattern over the surface and in the cytoplasm of TM cells | Human TM cell culture | 15 |
| MMP-2 expression in the TM cells colocalizes to podosome- or invadopodia-like structures | Human and porcine TM cell culture, human and porcine anterior segment organ culture | 22 |
| MMP-2 activity is increased in the TM within 24–72 hours post mechanical stretching, proportional to the degree of stretching | Human, bovine, and porcine TM cell culture | 12, 15, 21 |
| MMP-2 activity is decreased in the TM of POAG patients | Human TM cell culture (POAG) | 26 |
MMP-3 | Basal MMP-3 expression in the TM | Human and bovine TM cell culture, human corneoscleral explant culture | 11, 14, 15 |
| MMP-3 expression is increased in the TM within 24–72 hours post mechanical stretching | Human and bovine TM cell culture | 19, 21 |
| No changes in MMP-3 expression on mechanical stretching of the TM | Human TM cell culture | 15 |
| MMP-3 expression in anterior segment is increased in response to elevated IOP | Human perfused anterior segment organ culture | 18 |
MMP-9 | Basal MMP-9 expression in the TM | Human and bovine TM cell culture, human corneoscleral explant culture | 11, 15 |
| No basal MMP-9 expression in the TM | Human TM cell culture, human TM explant culture | 14 |
| Elevated IOP decreases MMP-9 activity in TM cells | Human TM cell culture | 23 |
| MMP-9 activity is decreased in the TM of POAG patients | Human TM cell culture (POAG) | 26 |
MMP-10 | MMP-10 expression in the TM is increased upon mechanical stretching | Human TM cell culture | 19 |
MMP-11, MMP-12 | Basal MMP-11 and ‐12 expression in the TM | Human TM cell culture, human TM explant culture | 14 |
MMP-14 | Basal MMP-14 expression in the TM | Human TM cell culture, human TM explant culture | 14 |
| Punctuate MMP-14 immunostaining pattern over the surface and in the nuclei of TM cells | Human TM cell culture | 15 |
| MMP-14 expression in TM cells colocalizes to podosome- or invadopodia-like structures | Human and porcine TM cell culture, human and porcine anterior segment organ culture | 22 |
| MMP-14 expression in the TM is increased within 24-72 hours post mechanical stretching | Human and porcine TM cell culture | 12 |
MMP-15, MMP-16, MMP-17, MMP-19, MMP-24 | Basal MMP-15, ‐16, ‐17, ‐19, and ‐24 expression in the TM | Human TM cell culture, human TM explant culture | 14 |
TIMP-1 | Basal TIMP-1 expression in the TM | Human and bovine TM cell culture, human TM explant culture, human corneoscleral explant culture | 11, 14 |
| TIMP-1 expression levels remain unchanged during 72 hours of mechanical stretching | Bovine TM cell culture | 21 |
| Elevated IOP increases TIMP-1 expression in TM cells | Human TM cell culture | 23 |
TIMP-2 | Basal TIMP-2 expression in the TM | Human TM cell culture, human TM explant culture | 14 |
| Cytoplasmic and somewhat “fibril-associated” TIMP-2 immunostaining pattern in TM cells | Human TM cell culture | 15 |
| TIMP-2 expression is strongly decreased in the TM within 24–48 hours post mechanical stretching | Human TM cell culture | 15 |
| TIMP-2 expression remains unchanged during 72 hours of mechanical stretching | Bovine TM cell culture | 21 |
TIMP-3, TIMP-4 | Basal TIMP-3 and ‐4 expression in the TM | Human TM cell culture, human TM explant culture | 14 |