December 1966
Volume 5, Issue 6
Articles  |   December 1966
Electroretinographic abnormalities and advanced multiple sclerosis
Author Affiliations
    Department of Ophthalmology, Duke University Medical Center Durham, N.C.
Investigative Ophthalmology & Visual Science December 1966, Vol.5, 555-559. doi:
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      JAMES PITZER GILLS; Electroretinographic abnormalities and advanced multiple sclerosis. Invest. Ophthalmol. Vis. Sci. 1966;5(6):555-559.

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      © ARVO (1962-2015); The Authors (2016-present)

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Reduced electroretinographic responses were present in patients with advanced multiple sclerosis. The observed electroretinographic reduction, in general, paralleled the severity and duration of the optic atrophy. These decreased electroretinographic responses in patients with advanced multiple sclerosis were not in keeping with the normal or elevated electroretinographic responses observed in patients with sectioned optic nerves. These findings suggest that with multiple sclerosis there may be other factors affecting the retina than the lesions of the optic nerve


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