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Abstract
The effects of clinical disease of the retina, optic nerve, chiasm, and cerebrum upon the electrical activity of the retina (ERG) and the brain, as recorded at the occipital surface (VER), have been studied and compared to those obtained from the surface of the brain of cats surgically prepared with similar lesions. In both situations it is possible to detect variations from normal in the responses recorded. The use of the intact opposite eye or hemisphere as a control is of value in increasing the significance of the findings. A sinusoidally varying stimulus seems in some instances a more discriminating test of abnormality of function than a square wave or flash stimulus.