October 1969
Volume 8, Issue 5
Articles  |   October 1969
Histochemistry of Corneal Macular Dystrophy
Author Affiliations
    Department of Pathology, Institute of Ophthalmology, University of London, London, England
Investigative Ophthalmology & Visual Science October 1969, Vol.8, 475-483. doi:
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      ALEC GAENER; Histochemistry of Corneal Macular Dystrophy. Invest. Ophthalmol. Vis. Sci. 1969;8(5):475-483.

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      © ARVO (1962-2015); The Authors (2016-present)

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Histochemical investigation of 22 corneal discs removed from patients with hereditary macular dystrophy has revealed two types of lesion. One is granulated and lies within and around stromal keratocytes as well as in the endothelium, and is apparently composed of keratan sulfate and a hexose- or deoxyhexose-rich acidic mucosubstance. The other is intralamellar and probably consists of a similar periodate-reactive acidic polysaccharide but without appreciable keratan sulfate.


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