December 1970
Volume 9, Issue 12
Articles  |   December 1970
Experimental Myopia in Rabbits
Author Affiliations
    Department of Ophthalmology, Washington University School of Medicine, 660 S. Euclid, St. Louis, Mo
Investigative Ophthalmology & Visual Science December 1970, Vol.9, 926-934. doi:
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      TAKASHI TOKORO; Experimental Myopia in Rabbits. Invest. Ophthalmol. Vis. Sci. 1970;9(12):926-934.

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      © ARVO (1962-2015); The Authors (2016-present)

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About 1 diopter (D) myopic change was induced experimentally in rabbit eyes by raising the body temperature and increasing the intraocular pressure with a specially designed suction cup. The myopic changes only took place when the body temperature was 41 to 43° C, intraocular pressure was above 40 mm. Hg, and topical atropine was given. Eyes subjected to repeated high pressure after the initial experiment exhibited greater changes. It seemed that imbalance between the intraocular pressure and elastic properties of the eye coat produced myopia.


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