April 1970
Volume 9, Issue 4
Free
Articles  |   April 1970
Use of Hydrophilic Contact Lenses to Increase Ocular Penetration of Topical Drugs
Author Affiliations
  • STEPHEN R. WALTMAN
    Department of Ophthalmology, University of Florida College of Medicine, Gainesville, Fla.; Department of Ophthalmology, Washington University School of Medicine, St. Louis, Mo. 63110
  • HERBERT E. KAUFMAN
    Department of Ophthalmology, University of Florida College of Medicine, Gainesville, Fla.
Investigative Ophthalmology & Visual Science April 1970, Vol.9, 250-255. doi:
  • Views
  • PDF
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      STEPHEN R. WALTMAN, HERBERT E. KAUFMAN; Use of Hydrophilic Contact Lenses to Increase Ocular Penetration of Topical Drugs. Invest. Ophthalmol. Vis. Sci. 1970;9(4):250-255.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Hydrophilic contact lenses take up and release fluorescein from solution in a measurable manner. This is more rapid with Bionite than with the Soflens lenses. Bionite lenses, either untreated or pretreated with fluorescein, markedly increase the concentration of this drug in the anterior segment of the eye. This suggests that these lenses may be useful adjuncts in attaining and maintaining high drug concentrations in the eye without the use of frequent topical medication. The drug concentration attained with these lenses is higher than that possible with frequent topical medication alone.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×