The monoclonal antibodies (mAb) P1F6 (αvβ5 integrin), BV3 (αvβ3), and CRC54 (activated αvβ3 integrin) were purchased from Abcam (Cambridge, MA). mAb LM609 (total surface αvβ3 integrin) and M9 (αv integrin subunit) were purchased from Millipore Corp. (Temecula, CA). Alexa 488-conjugated goat-anti-mouse IgG, Hoescht 33342 nuclear stain, and pHrodo Red S. aureus bioparticles were purchased from Invitrogen (Carlsbad, CA). Mouse IgG1 negative isotype control was purchased from BD Biosciences (San Jose, CA). mAb GAL-13 against β-galactosidase was purchased from Sigma-Aldrich (St. Louis, MO). siRNA against human αvβ5 integrin (ON-TARGETplus SMARTpool, Human ITGB5) and nontargeting siRNA (ON-TARGETplus Nontargeting siRNA#1) were purchased from Dharmacon (Lafayette, CO). Focal adhesion kinase (FAK) inhibitor 14 was purchased from Santa Cruz Biotechnology (Dallas, TX).