Abstract
Purpose:
To evaluate the fluorescein angiography (FA) findings of retinal vein occlusion (RVO) by using ultra-widefield scanning laser ophthalmoscope (Optos®200Tx).
Methods:
Ultra-wide field FA was performed on 31 eyes of 31 patients with branch retinal vein occlusion (BRVO) (13 male, 18 female, average age 67.4±8.5 years) and 11 eyes of 11 patients with central retinal vein occlusion (CRVO) (3 male, 8 female, average age 67.0±13.9 years). Twelve eyes of 12 patients after photocoagulation treatment (BRVO 8 eyes, CRVO 4 eyes) were also examined. The fundus was divided to three zones; posterior pole, mid-periphery, and far-periphery. The location and the size of capillary non-perfusion area (NPA) were evaluated.
Results:
In BRVO patients, 19 eyes (61%) exhibited NPA at the same quadrant where the vein occlusion existed. Furthermore, 14 eyes exhibited NPA in the far-peripheral retina. In 2 eyes (6%), the vascular leakage was found in the peripheral retina in the quadrant where the vein occlusion did not exist. In CRVO patients, NPA was found in 5 eyes (45%). The ratio of NPA to the whole image was calculated in order to quantify the degree of ischemia, which ranged from 1% to 89%. In post-photocoagulation group, untreated NPA was found in 8 eyes (BRVO 5 eyes, CRVO 3eyes).
Conclusions:
Ultra-widefield FA was very useful to evaluate the retinal capillary perfusion status in RVO patients. Hyperpermeability of retinal vessels in the periphery was found in the area distant from the retinal vein occlusion.
Keywords: 688 retina •
550 imaging/image analysis: clinical