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Benjamin Potsaid, Jonathan Liu, WooJhon Choi, Ireneusz Grulkowski, Vijaysekhar Jayaraman, James Jiang, Peter Heim, Jay Duker, Alex Cable, James Fujimoto; VCSEL Laser Technology for Ultrahigh Speed and Extended Depth Range OCT Imaging of the Retina and Anterior Eye. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1491. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
MEMS tunable Vertical Cavity Surface Emitting Laser (VCSEL) technology achieves a combination of ultrahigh sweep speeds, wide spectral tuning range, adjustability in sweep trajectory, and extremely long coherence length, which cannot be simultaneously achieved with any other OCT light source technology. This investigation demonstrates the unique advantages of the VCSEL for ultrahigh speed, ultralong depth range, and phase sensitive ophthalmic OCT imaging at 1065nm and 1310nm wavelengths.
A reconfigurable 1065nm swept source/Fourier domain prototype OCT instrument with 20kHz -1.2MHz axial scan rate was developed to perform retinal and anterior segment imaging, as well as full eye length measurement. A second instrument operating at 1310nm was developed to perform anterior segment imaging.
The high speeds of the VCSEL enable acquisition of wide field, densely sampled retinal volumes with minimal motion artifacts (Fig. 1A). The record coherence length of the VCSEL enables long depth range imaging (Fig. 1B). It is possible to acquire single data sets extending from the cornea to the retina using an ultralong depth range imaging mode. Using phase sensitivity OCT, quantitative Doppler blood flow information can be obtained at high acquisition speeds to capture fast flow (Fig. 2A and 2B). Doppler angiography techniques to visualize capillaries can also be performed by using the high axial scan speeds.
MEMS tunable VCSEL technology for Swept Source OCT exhibits a unique combination of high imaging speed, adjustablity in operating parameters, and long imaging range, which promises to improve visualization of disease relevant ocular features, enable new OCT imaging capability, and improve patient work flow in the clinic by allowing multipurpose OCT imaging instrumentation.
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