June 2013
Volume 54, Issue 15
ARVO Annual Meeting Abstract  |   June 2013
Comparison of biomechanical properties of cornea in diabetic and nondiabetic primary open angle glaucoma patients
Author Affiliations & Notes
  • Faruk Ozturk
    Ulucanlar Eye Hospital, Ankara, Turkey
  • Serkan Akkaya
    Yildirim Beyazit Hospital, Ankara, Turkey
  • Ertugrul Can
    Ondokuz Mayis University, Samsun, Turkey
  • Footnotes
    Commercial Relationships Faruk Ozturk, None; Serkan Akkaya, None; Ertugrul Can, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 1640. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Faruk Ozturk, Serkan Akkaya, Ertugrul Can; Comparison of biomechanical properties of cornea in diabetic and nondiabetic primary open angle glaucoma patients. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1640.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Purpose: To investigate corneal biomechanical properties in primary open angle glaucoma patients with and without diabetes mellitus (DM), and to evaluate the effect of metabolic control and duration of DM on biomechanical properties of cornea.

Methods: A total of 101 eyes of 101 primary open-angle glaucoma (POAG) patients (60 with diabetes and 41 without diabetes) were recruited in this prospective study. After a complete ophthalmic examination, corneal hysteresis (CH) and corneal resistance factor (CRF) of the patients were measured by the ocular response analyzer (ORA). Central corneal thickness (CCT) measurements were measured with ultrasound pachymeter. Glucolysed haemoglobine (HbA1c) measurements of the patients were made on the same day as ophthalmic assessments were performed.

Results: CRF measurements in diabetic group were found to be statistically significant compared to control group (p=0,01). There were no statistically significant differences between two groups regarding CCT and CH measurements (p=0,37 for CCT and p=0,11 for CH). In diabetic group, the correlation analyses showed that CH and CRF were not significantly correlated with HbA1c levels and duration of diabetes.

Conclusions: Significant increase in CRF measurements in diabetic POAG patients and absence of any statistically significant difference in CCT measurements suggest that there would be some corneal biomechanical changes related to increased corneal stiffness which is depicted by the increase of CRF values parallel to failure of corneal hydration. It was found that duration and metabolic control of diabetes did not change the biomechanical properties of cornea.

Keywords: 480 cornea: basic science • 499 diabetic retinopathy • 627 optic disc  

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.