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Roland Lee, Toshimitsu Kasuga, Qi Cui, Shan Lin; Narrower Angles Are Associated with Greater Angle Opening After Laser Peripheral Iridotomy. Invest. Ophthalmol. Vis. Sci. 2013;54(15):1850. doi: https://doi.org/.
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To evaluate the association between baseline and laser peripheral iridotomy (LPI) induced opening of anterior chamber angle width.
Anterior segment optical coherence tomography images captured before and after LPI were analyzed to determine the angle opening distance at 250μm (AOD250), 500μm (AOD500), 750μm (AOD750) from the scleral spur, trabecular-iris space area at 500 μm (TISA500) and 750μm (TISA750) from the scleral spur, and angle recess area at 750μm (ARA750) from the scleral spur. Differences in preoperative and postoperative measurements for anterior chamber angle width parameters were compared by paired Student’s t-tests. Linear mixed-effects regression models, adjusted for age, sex, preoperative pupil diameter, preoperative central corneal thickness, preoperative anterior corneal curvature, preoperative posterior corneal curvature, and the use of both eyes in the same subject, were used to examine the association between baseline and LPI induced opening of anterior chamber angle width parameters.
Eighty-four eyes of 52 primary angle closure suspects were included in the analysis. AOD250, AOD500, AOD750, TISA500, TISA750, and ARA750 significantly increased following LPI (all P<0.0001). Lower baseline measurements were significantly associated with greater postoperative opening in all anterior chamber angle width parameters (all P<0.005).
Our results showed opening of the anterior chamber angle width after LPI and demonstrated an inverse association between baseline and LPI-induced opening of the anterior chamber angle width, specifically showing that eyes with a more crowded anterior chamber angle undergoing LPI were correlated with a greater magnitude of increase in anterior chamber angle width after the procedure.
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