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José Ignacio Fernández-Vigo, CRISTINA FERNANDEZ-VIGO ESCRIBANO, Javier García Bella, Jose Martinez de la Casa, Julian Garcia-Feijoo, José Fernández-Vigo López, GLAUCOMA, HOSPITAL CLINICO SAN CARLOS, MADRID; Descriptive study of the anterior chamber angle using anterior segment Fourier Domain OCT and its relationship to the morphometry of the eye in the normal population. Invest. Ophthalmol. Vis. Sci. 2013;54(15):2273.
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To measure the anterior chamber angle width with OCT and analyze its relationship with the morphometric variables of the eye in a normal population.
Prospective study of one eye from 320 consecutive healthy patients. We examined the patients with Pentacam ®, IOL Master ®, and RTVue ® (Optovue, California, USA) anterior segment Fourier Domain OCT (AS-OCT). Images were obtained under standard light conditions, and when the signal strength intensity was greater than 30. Parameters evaluated: age, sex, IOP, refractive error, axial length, pupil diameter and pachymetry. . Anterior chamber (AC) parameters examined were: depth, volume and diameter. Angle parameters: nasal and temporal width measured in degrees, angle opening distance (AOD), trabecular iris space area (TISA) and iris thickness; length, thickness and area of the trabecular meshwork (TM). Pearson correlation analysis was performed to study the correlation between the AC angle and the rest of the variables.
19 patients (6%) were excluded because the angle width could not be measured due to low image quality. The mean values of the population were: age: 45 ± 14.2 years (range 19 to 84), IOP: 15.92 ± 3.8 mmHg (range 8 to 26.4), sphere: -0.4 ± 2.79 diopters (range -6.25 to 6.5), axial length: 23.91 ± 1.51 mm (range 20.03 to 29.14), AC depth: 3.42 ± 0.43 mm (range 2.45 to 4.38), AC diameter: 11.93 ± 0.39 mm (range 11 to 13), iris thickness: 412.6 ± 88.88 microns (range 195 to 910), pupil diameter 2.96 ± 0.62 (1.71 to 5.51). The mean temporal angle width was 38.8 ± 12.7 degrees (range 14.5 to 78.2), AOD: 587.18 ± 261.65 microns, (range 64 to 1440), TISA: 0.201 ±0.093 mm2 (range 0.027 to 0.519). We found a correlation between the angle and the depth of the AC (r = 0.76), with the axial length (r = 0.68), with the spherical refractive error (r = -0.68), with age (R = -0.60), and weakly with the IOP (r = -0.17). Cited correlations were statistically significant (p <0.05%).
SA Fourier Domain OCT enabled us to analyze and measure the chamber angle in 94% of eyes. We found a strong correlation between the angle width and depth of the AC, spherical refractive error and age, and weak with the IOP.
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