June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Incidence of Endogenous Intraocular Inflammation in the Central Tokyo of Japan for 8 Years from 2004 to 2012
Author Affiliations & Notes
  • Motoko Serizawa
    Opthalmology, Nippon Medical School, Bunkyo-ku, Japan
  • Yukiko Ito
    Opthalmology, Nippon Medical School, Bunkyo-ku, Japan
  • Reiko Tsukada
    Opthalmology, Nippon Medical School, Bunkyo-ku, Japan
  • Hiroshi Takahashi
    Opthalmology, Nippon Medical School, Bunkyo-ku, Japan
  • Hiroko Taniguchi
    Opthalmology, Nippon Medical School, Bunkyo-ku, Japan
  • Junko Hori
    Opthalmology, Nippon Medical School, Bunkyo-ku, Japan
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 2526. doi:
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      Motoko Serizawa, Yukiko Ito, Reiko Tsukada, Hiroshi Takahashi, Hiroko Taniguchi, Junko Hori; Incidence of Endogenous Intraocular Inflammation in the Central Tokyo of Japan for 8 Years from 2004 to 2012. Invest. Ophthalmol. Vis. Sci. 2013;54(15):2526.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To report the clinical statistical analysis of patients with endogenous intraocular inflammation in the central Tokyo for 8 years from 2004 to 2012.

Methods: This retrospective study involved 789 new patients with endogenous intraocular inflammation who visited Nippon Medical School Hospital for 8 years from April 2004 to October 2012.

Results: The subjects comprised 374 men and 415 women. The ratio of men to women was 1:1.1. The age averaged 50.7±16.7years. Definitive diagnosis was made in 503 cases (63.8%). The most frequent clinical entity was sarcoidosis (17.5%), followed by scleritis (12.9%), Vogt-Koyanagi-Harada disease (4.6%), herpetic iridocyclitis without acute retinal necrosis (4.6%), human leukocyte antigen (HLA)-27-associated uveitis (3.0%), Behçet’s disease (2.5%). The subjects were classified into four groups; adolescent (0-19 years), young (20-39), middle-aged (40-59), and old (60 years and older). The most frequent clinical entity of adolescent group was juvenile reumathoid arthritis -asssociated iridocyclitis. In other age group, sarcoidosis was the most frequent. This study was also classified into 4 parts of intraocular inflammation. Anterior uveitis was the most frequent, compared with intermediate, posterior, and pan-uveitis. The incidence of secondary glaucoma was 26.5%, and steroid responder was about 30% among of them.

Conclusions: Generally, sarcoidosis, Vogt-Koyanagi-Harada disease, and Behçet’s disease are the most frequent intraocular inflammations in Japan. The characteristic of this study was that scleritis and herpetic iridocyclitis were also frequent intraocular inflammation at Nippon Medical School Hospital.

Keywords: 432 autoimmune disease • 462 clinical (human) or epidemiologic studies: outcomes/complications  
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