June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Notching of tissue after macular hole surgery : An abrupt alteration in inner contour of parafoveal tissue associated with foveal tissue elongation
Author Affiliations & Notes
  • Jae Hui Kim
    Ophthalmology, Samsung Medical Center, Seoul, Republic of Korea, Seoul, Republic of Korea
  • Se Woong Kang
    Ophthalmology, Samsung Medical Center, Seoul, Republic of Korea, Seoul, Republic of Korea
  • Jaeryung Kim
    Ophthalmology, Samsung Medical Center, Seoul, Republic of Korea, Seoul, Republic of Korea
  • Footnotes
    Commercial Relationships Jae Hui Kim, None; Se Woong Kang, None; Jaeryung Kim, PharmAbcine, Inc. (F)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 2802. doi:
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      Jae Hui Kim, Se Woong Kang, Jaeryung Kim; Notching of tissue after macular hole surgery : An abrupt alteration in inner contour of parafoveal tissue associated with foveal tissue elongation. Invest. Ophthalmol. Vis. Sci. 2013;54(15):2802.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To investigate the significance of notching in parafoveal tissue after surgery for macular hole (MH).

 
Methods
 

This retrospective, observational case series included 35 eyes from 35 patients who underwent surgery for MH. Distance between the parafoveal edge of the outer plexiform layer (OPL) in optical coherence tomography image (OCT) was defined as the inter-OPL distance. The horizontal and vertical inter-OPL distance was divided into nasal and temporal length, and superior and inferior length, respectively. The inter-OPL distance was measurable in 22 eyes. In these eyes, all the nasal, temporal, superior, and inferior lengths were divided into two groups according to presence of the notching of tissue on OCT image at postoperative 6 to 8 months. The difference in inter-OPL distance between 5.4 ± 4.5 weeks postoperatively in average and 6.6 ± 0.8 months postoperatively in average was compared between the two groups.

 
Results
 

The mean MH size was 436.6 ± 209.7 μm. The notching of tissue was noted in 26 eyes (74.3%) regardless of MH size; nasal direction=22 eyes (62.9%), temporal direction=10 eyes (28.6%), superior direction=12 eyes (34.3%), inferior direction=14 eyes (40.0%). In the 22 eyes, the mean difference in length was 82.4 ± 72.1 μm and 47.9 ± 60.6 μm in the directions with and without the notching of tissue. The difference in the distance was significantly greater in the directions with notching (P=0.017).

 
Conclusions
 

The presence of notching could be a tomographic marker for the development of the elongation in foveal tissue after MH surgery. Presence of the notching regardless of MH size suggests that postoperative elongation of foveal tissue occurs in large MHs as well as in small MHs.

 
 
Optical coherence tomography images showing notching of tissue in the superior direction 6 months after macular hole surgery. Notching of tissue was defined as an abrupt alteration in inner contour of tissue (arrow). When compared to the opposite direction, definite elongation of outer nuclear layer in the direction of the notching was observed (arrowheads).
 
Optical coherence tomography images showing notching of tissue in the superior direction 6 months after macular hole surgery. Notching of tissue was defined as an abrupt alteration in inner contour of tissue (arrow). When compared to the opposite direction, definite elongation of outer nuclear layer in the direction of the notching was observed (arrowheads).
 
Keywords: 586 macular holes • 688 retina  
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