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tasuku yoneda, Manabu Yamamoto, Takeya Kohno, Yusaku Yoshida, Ayako Yasui, Kunihiko Shiraki; Fundus autofluorescence at macular hole predicting postoperative visual acuities. Invest. Ophthalmol. Vis. Sci. 2013;54(15):2814.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate a relationship between the preoperative fundus autofluorescence (FAF) at macular hole (MH) and the postoperative visual acuity after MH surgery
The subjects were 20 eyes of 18 patients (8 eyes of 6 males, 14 eyes of 14 females; age range 54-78 years, mean 64.8 years) with primary Gass stage 4 MH who underwent vitrectomy between August 2007 and July 2009. These eyes were monitored at least for 3 months. Eyes where MH closure was unsuccessful after the initial surgery, those which had previously undergone vitreous surgery, and those with a history of other macular disorders had been excluded. Preoperative FAF was imaged with a fundus camera (FC-FAF) and a confocal scanning laser ophthalmoscope (SLO-FAF), and the ratio (M-D ratio) of FAF brightness at the bottom of the MH to that at the optic disc was calculated. The relationships between the postoperative visual acuity up to 12 months and the M-D ratio, age, gender, preoperative best corrected visual acuity, estimated time that had elapsed before surgery, and macular hole diameter were investigated. logMAR visual acuity was converted from decimal visual acuity.
Of the 20 eyes, 15 (75%) were monitored for 6 months and 13 eyes (65%) for 12 months. Mean logMAR visual acuity was 0.63 at baseline, 0.33 at 1 months, 0.32 at 3 months, 0.30 at 6 months, and 0.27 at 12 months postoperatively, with significant improvements seen after 1 months (p<0.01). The factor correlated with the postoperative visual acuity was the M-D ratio on FC-FAF, which was significantly correlated with visual acuity 6 and 12 months postoperatively (p=0.01 and 0.02, r =0.66 and 0.67, respectively). There were no correlations with any other factors.
The M-D ratio on preoperative FC-FAF can be a predictor for postoperative visual acuity achieved after long-time follow-up.
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