Intracameral moxifloxacin for prophylaxis of endophthalmitis after cataract surgery: A case Series

Abstract

Purpose: To compare endophtalmitits rates post routine cataract surgery with IOL implantation in patients with or without intracameral moxifloxacin 0.5% at the end of surgery

Methods: A retrospective study was conducted from January 2009 to November 2012 in San Camilo public eye center in Berazategui( Buenos Aires; Argentina) evaluating 6001 cataract surgeries performed by fellows . From 2009 to 2010 a total of 2941 eyes had routine cataract surgery with IOL implantation and no intracameral moxifloxacin at the end of surgery. From January 2011 to November 2012 a total of 3060 eyes had cataract surgery with IOL implantation and intracameral moxifloxacin 0.5% 0.1 ml whitout dilution at the end of surgery.

Results: Three cases of endophthalmitis ocurred in 6001 cataract surgeries. All cases were reported during the 2009-2010 period, and received the proper treatment. No cases were reported during the 2011-2012 period

Conclusions: No adverse effects were observed after intracameral injection of moxifloxacin 0.5% ophthalmic solution at the conclusion of routine cataract surgery. The overall rate of endophthalmitis was reduced from 0.1 % to 0%. It was found very effective for the prophylaxis of endophthalmitis at the conclusion of routine cataract surgery.

Keywords: 445 cataract • 513 endophthalmitis • 503 drug toxicity/drug effects