Patient Satisfaction and Quality of Vision after Wavefront-guided (WFG) vs. Wavefront-optimized (WFO) LASIK

Abstract

 

Purpose

 

To compare higher order aberration (HOA) root mean square (RMS) and patient satisfaction of postoperative vision after WFG vs. WFO LASIK.

 

Methods

 

Participants randomized to receive WFG LASIK (VISX Star S4, Abbott Medical Optics) or WFO LASIK (Wavelight Allegretto Wave Eye-Q, Alcon Surgical) underwent testing to determine their HOA RMS preoperatively and at 6 months (M) postoperatively. RMS HOA were analyzed at four different pupil sizes (4, 5, 6, and 7mm) using Complete Ophthalmic Analysis System (COAS, Abbott Medical Optics). A repeated measures analysis of variance (RM-ANOVA) was used to compare WFG vs. WFO LASIK HOA RMS at each pupil size over time. Participants responded to a questionnaire preoperatively and 6M postoperatively. A Mann-Whitney test was used to compare patient satisfaction of postoperative vision. A p-value <0.05 was considered statistically significant.

 

Results

 

LASIK was performed on 18 WFG and 17 WFO participants. Differences in preoperative age or manifest spherical equivalent (MSE) were as follows: Age: 30.7 ±7.5 years (y) WFG vs. 32.6 ±8.8y WFO, p=0.34; MSE: -2.96±0.97 Diopters (D) WFG vs. -3.62±1.57 WFO, p=0.04. MSE at 6M was 0.04±0.27 WFG vs. -0.02±0.26 WFO, p=0.33. Results of HOA RMS analysis at each pupil size, over time are presented in Figure 1. Comparing WFG vs. WFO over time at each pupil size p=0.75, 0.80, 0.74, 0.24 at 4mm, 5mm, 6mm, and 7mm respectively. Results from the questionnaire are presented in Table 1.

 

Conclusions

 

Results show there is no significant difference in RMS HOA when comparing WFG vs. WFO LASIK over time. Questionnaire results also showed no significant difference when assessing expected visual outcomes in WFG vs. WFO LASIK. Ongoing testing in this study will determine if either WFG or WFO generated optical quality affects military task performance.

 

 

Figure 1. WFG vs. WFO LASIK higher order aberrations (HOA) root mean square (RMS)

 

 

Table 1. Patient satisfaction and quality of vision questionnaire results.

 

Keywords: 683 refractive surgery: LASIK • 669 quality of life • 679 refractive surgery: comparative studies