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Guang-ming Dai; Modeling of Human Refractions for Refractive Surgery. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3132. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the statistical distribution of sphere and cylinder for refractive surgical candidates.
Based on population statistics for 393,139,704 eyes in a 2006 national survey and a refractive surgery patient database for 8,246,757 eyes performed in the US until 2006, a statistical analysis was performed. For refractive sphere, a normal distribution is a reasonable measure for virgin eyes. For refractive surgical candidates, however, a Rayleigh distribution better represents the statistics as emmetropic patients do not seek refractive surgery (except for presbyopes). For refractive cylinder, a normal distribution is a reasonable measure for both the virgin eyes and refractive surgical candidates. These statistical models were used to generate random eyes for scientific research or commercial use.
One million random normal eyes and one million refractive surgical eyes were generated based on the proposed algorithms. Roughly 79% eyes are myopic, 13% are hyperopic and 7% are mixed astigmatic. The statistics of the simulated eyes follow the statistics assumed. This allows a “real-world” testing, or a “simulated clinical trial” for the development of new treatment algorithms, or verification and validation of to-be-released treatment software products, greatly speeds up the process and improves the efficiency for product development in a commercial environment. It may also be used in the vision research when a large number of eyes are required for statistical analysis.
The refractions of human eyes (sphere and cylinder) follow the proposed statistical distribution based on a large national optometric database. Simulation based on the statistics provides a useful means for vision research and commercial use.
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