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Riccardo Scotto, Marina Papadia, Alessandro Bagnis, Carlo Enrico Traverso; Evaluation Of The Interface Between Keratoprosthesis and Donor Cornea By Anterior Segment OCT. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3476.
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The synthetic Keratoprosthesis can restore visual function in patients affected by corneal blindness that are poor candidates for keratoplasty. Advances in medical treatment have resulted in a marked improvement in retention rates and visual outcomes. Anterior Segment (AS) OCT imaging provides additional information about the status of the prosthesis and the donor graft cornea.
AS-OCT imaging was performed at every follow-up visit to analyze prosthesis structure, iris position and interface between device and donor cornea.
Five eyes of 5 patients implanted with the Boston type I keratoprosthesis, between 2008 and 2011, were included in this retrospective analysis. Mean corneal thickness near the prosthesis was 626 ±34 μm (range 549-694 μm) in the nasal sector, and 643 ±59 μm in the temporal sector (range 571-657 μm).
Spectral-domain AS-OCT allows high resolution imaging of the keratoprosthesis device-donor cornea interface, precise visualization of the iris profile and quantification of the irido-corneal angle. This imaging technique, able to provide high-resolution images of the anterior segment, can help identify the risk for keratoprosthesis-related complications, such as corneal melting and angle closure glaucoma.
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