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Jessica Adefusika, Cheryl Khanna; Incidence of trabeculectomy related complications at various Mitomycin C Concentrations from 1985 to 2010 in Olmsted County, MN. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3495.
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There have been increasing concerns over complications occurring from trabeculectomy subsequently leading to a decrease in this practice with a concurrent increase in tube-shunt procedures. In this study, we determined the incidence of complications associated with trabeculectomy without mitomycin C and at different mitomycin C concentrations between 1985 through 2010 in Olmsted County, MN.
This is a retrospective, population-based, longitudinal study of residents of Olmsted County, Minnesota, who underwent a trabeculectomy from 1985 to 2010. Complications related to trabeculectomy and dose of mitomycin C are reported.
Ten out of 361 patients who underwent trabeculectomy for glaucoma treatment during the study time period were found to have developed endophthalmitis. The incidence rate of endophthalmitis post trabeculectomy was calculated as 2.7%.
The rate of endophthalmitis post trabeculectomy in Olmsted County is lower than other published reports. We attribute the low incidence rate of complications to the lower mitomycin C concentration of 0.2mg/ml employed at this institution.
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