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Sakina Kashani, Katherine Meagher, Stephen Beatty, David Thurnham, Alan Howard, John Nolan; An Investigation into Declared vs Actual Content of Commercially Available Food Supplements Containing the Macular Carotenoids. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3772.
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The macular carotenoids lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) are commercially available in a variety of food supplements. These supplements are promoted to support eye health and wellbeing. The purpose of this study is to analyse these supplements in order to test concordance between declared and actual content of the respective macular carotenoids.
20 commercially available food supplements claiming content of L, and/or Z, and/or MZ (some with co-antioxidants) were selected for carotenoid analysis by high performance liquid chromatography (HPLC). 3 capsules/tablets were selected at random from each packet.
Table 1 presents the declared vs (average) measured macular carotenoid content of seven supplements tested.
The observed discrepancies between actual and alleged concentrations of the respective macular carotenoids, and the identification of the presence of MZ in commercially available preparations is particularly important when such formulations are used for research.
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