June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Performance of the Visual Field Index in Patients with Advanced Field Loss
Author Affiliations & Notes
  • Meera Ramanathan
    Ophthalmology, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA
  • Jun Mo Lee
    Ophthalmology, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA
  • Nila Cirineo
    Ophthalmology, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA
  • Abdelmonem Afifi
    Biostatistics, Karin Fielding School of Public Health, University of California at Los Angeles, Los Angeles, CA
  • Esteban Morales
    Ophthalmology, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA
  • Fei Yu
    Ophthalmology, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA
    Biostatistics, Karin Fielding School of Public Health, University of California at Los Angeles, Los Angeles, CA
  • Kouros Nouri-Mahdavi
    Ophthalmology, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA
  • Anne Coleman
    Ophthalmology, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA
    Epidemiology, Karin Fielding School of Public Health, University of California at Los Angeles, Los Angeles, CA
  • Joseph Caprioli
    Ophthalmology, Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA
  • Footnotes
    Commercial Relationships Meera Ramanathan, None; Jun Mo Lee, None; Nila Cirineo, None; Abdelmonem Afifi, None; Esteban Morales, None; Fei Yu, None; Kouros Nouri-Mahdavi, Allergan (C); Anne Coleman, None; Joseph Caprioli, Allergan Inc. (C), Allergan Inc. (F), Allergan Inc. (R)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 3929. doi:
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      Meera Ramanathan, Jun Mo Lee, Nila Cirineo, Abdelmonem Afifi, Esteban Morales, Fei Yu, Kouros Nouri-Mahdavi, Anne Coleman, Joseph Caprioli; Performance of the Visual Field Index in Patients with Advanced Field Loss. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3929.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

The purpose of this study is to explore the relationship between the Visual Field Index (VFI) and the visual field mean deviation (MD), determined by analyzing the change in VFI (ΔVFI) with change in MD (ΔMD) in patients with advanced damage.

 
Methods
 

The MD and VFI values obtained from visual field tests conducted on 176 eyes of 168 glaucoma patients having an MD around -20dB were studied. A total of 535 exams from 1984 to 2011 with MD values within the range of -16dB to -24dB were included. Two divisions were made with the first having serial MDs all less than or greater than -20 dB and the second with serial MDs crossing -20 dB. The relationship of ΔVFI with ΔMD was evaluated.

 
Results
 

The means (±SD) for the ΔVFI are 6.47 (±9.17) corresponding to MDs on either side of -20dB and 15.41 (±7.64) corresponding to MDs crossing -20dB (p<0.0001). For ΔVFI/ΔMD, these values are 6.47 (±9.17) when the range of MD falls on either side of -20 dB, and 8.12 (±6.78) when the range of MD crosses the -20 dB value (p<0.00026).

 
Conclusions
 

The value of the VFI becomes highly variable with MDs crossing -20dB in comparison to those VFIs corresponding to MDs on either side of -20dB. The reason for this effect is the change from use of pattern deviation to total deviation values in calculation of VFI at the MD boundary of -20dB. The development of methods to measure visual field rates that are free from this boundary effect would be desirable.

 
 
Figure 1. This plot is an example of a given patient’s pattern of MD progression and corresponding VFI fluctuation.
 
Figure 1. This plot is an example of a given patient’s pattern of MD progression and corresponding VFI fluctuation.
 
 
Figure 2. A representation of the relationship between ΔVFI and ΔMD for the 176 eyes in the study.
 
Figure 2. A representation of the relationship between ΔVFI and ΔMD for the 176 eyes in the study.
 
Keywords: 758 visual fields  
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