June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Detection of Functional Defect in Early Glaucoma using Standard Automated Perimetry and Flicker Defined Form Perimetry
Author Affiliations & Notes
  • Yuan-Hao (Derek) Ho
    School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada
  • John Flanagan
    School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada
    Department of Ophthalmology & Vision Science, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
  • Footnotes
    Commercial Relationships Yuan-Hao (Derek) Ho, None; John Flanagan, Heidelberg Engineering (C), Heidelberg Engineering (R), Heidleberg Engineering (F), Carl Zeiss Meditec (C), Carl Zeiss Meditiec (R), Carl Zeiss Meditiec (R), Alcon Pharmaceuticals (R), Alcon Pharmaceuticals (R), Optovue Inc (F), Optovue Inc (F), Photon etc (F), Photon etc (F)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 3951. doi:https://doi.org/
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      Yuan-Hao (Derek) Ho, John Flanagan; Detection of Functional Defect in Early Glaucoma using Standard Automated Perimetry and Flicker Defined Form Perimetry. Invest. Ophthalmol. Vis. Sci. 2013;54(15):3951. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To compare the detection of functional loss in early glaucoma using standard automated perimetry and flicker defined form perimetry.

Methods: 156 early-moderate glaucomatous subjects were recruited (average age: 62.6±11.0; 75 male, 78 OD). Humphrey Field Analyzer (HFA) SITAStd 24-2 classified subjects as 130 early glaucoma eyes and 26 moderate glaucoma eyes using a modified Hodapp criteria (MD: -2.12±2.04dB; PSD: 2.56±1.78dB). The Heidelberg Edge Perimetry (HEP) was used to perform both standard automated perimetry (HEP-SAP) and flicker defined form perimetry (HEP-FDF). Of note is that both forms of perimetry share the identical normative database. Participants were tested at 3 visits within a 3 month period, including HFA SITAStd 24-2 (visit 1), HEP-SAP ASTAStd 24-2 (visit 2&3) and HEP-FDF ASTAStd 24-2 (all visits). Unreliable visual fields were excluded from the study.

Results: The HEP-FDF gave more defects (2514 PD less than 5%, 1568 less than 1%, 1357 less than 0.5%; MS:13.33±6.34 dB) than HEP-SAP (1817 PD less than 5%, 833 less than 1%, 647 less than 0.5%; MS: 27.89 ±3.91 dB). Test re-retest characteristics were similar for both HEP-FDF(r=0.82, MoD=-0.43, CoR=7.47) and HEP-SAP(r=0.75,MoD=-0.15, CoR=5.45) in our study. Test time was significantly (p<0.001) longer for HEP-FDF (463.12±150.97 sec) than HEP-SAP (353.19±75.84 sec), due to the larger number of field defects detected by HEP-FDF.

Conclusions: Visual field defects were detected earlier by HEP-FDF when compared to HEP-SAP in early glaucoma. Both tests gave similar test-retest characteristics. There was a similar test time for similar amounts of defect. The greater the defect the longer the test time.

Keywords: 758 visual fields • 642 perimetry • 612 neuro-ophthalmology: diagnosis  
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