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Naoto Hanyuda, Taku Sato, Ryo Mukai, Shoji Kishi; Autofluorescence and OCT of Retinal pigment epithelial tears. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4087.
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© ARVO (1962-2015); The Authors (2016-present)
To determine using optical coherence tomography (SD-OCT), fundus autofluorescence (FAF) that factors of poor visual acuity of retinal pigment epithelial tear (RPE tear) after treatment for exudative age-related macular degeneration (AMD).
A total of 182 patients (183 eyes) who were treated by PDT combined with anti-VEGF for exudative AMD. 7 eyes (3.8%) developed RPE tear following therapy. 5 eyes of 7 eyes were observed using optical coherence tomography (SD-OCT), fundus autofluorescence (FAF). We evaluated characteristics of the onset of RPE tear, and the changes of the findings .
In all cases FAF showed absence of autofluorescense in the area of denuded RPE and showed hyperfluorescense in the role of the RPE. In 3 eyes of 5 eyes the area of denuded RPE changed hypofluorescense area in FAF. In 2 eyes of 5 eyes proliferation of RPE was observed in SD-OCT.
RPE tears changed from absence of autofluorescense in the area of denuded RPE to hypofluorescense area in FAF. We confirmed re-growth of RPE in SD-OCT.
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