Six-month Report of Selective Retina Therapy on Central Serous Chorioretinopathy in Japanese Patients

Abstract

Purpose: To investigate the six-month result of Selective Retina Therapy (SRT) for Japanese patients with central serous chorioretinopathy (CSCR).

Methods: Seventeen eyes of 17 CSCR patients consisting of 11 males and 6 females were treated. Mean age was 55 years old (range 37-78 years old). All subjects had leakage measured by fluorescein angiography (FA) and persistent serous retinal detachment at the subfovea longer than 3 months. SRT laser (frequency-doubled, pulse-stretched Nd:YLF laser; 527 nm, 1.7 µs pulse duration, 100-Hz repetition rate, Medical Laser Center Lübeck, Germany) was used for treatment. Following test spots to determine the damage around the upper or lower vessel arcade, the treatment was performed at the leakage point on FA. Best corrected visual acuity (BCVA) examination, FA and optical coherence tomography (OCT) were performed at baseline, three and six months postoperatively. The change of serous retinal detachment (SRD) was evaluated by measuring central macular thickness (CMT) with OCT. The numbers of retreatment eyes were also examined while this follow-up period.

Results: The mean logMAR BCVA was 0.10, 0.03 and 0.06 at baseline, 0.03, 3 months and 6 months respectively (P<0.05 at 3 months, 0.29 at 6 months; as compared with baseline). The mean CMT was 369μm, 274μm and 257μm at baseline, 3 months and 6 months respectively (P<0.001 at 3 months, <0.001 at 6 months; as compared with baseline). The SRD at the fovea disappeared in 8 eyes (47%) at 3 months and 13 eyes (76%) at 6months. The leakage on FA disappeared in 7 eyes (41%) 3 months and 13 eyes (76%) at 6 months. The numbers of retreatment eyes were 10 (59%) at 3months and 4 (24%) at 6months.

Conclusions: SRT was still effective for 6 months follow-up for the conservation of the visual acuity and the decrease of the subfoveal fluid.

Keywords: 578 laser • 701 retinal pigment epithelium • 688 retina