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Juan Giralt, Ricardo Casaroli-Marano, Anniken Burés-Jelstrup, Rafael Navarro, Jose Juan Martinez-Toldos, Christian Fernandez-Martinez, MSocorro Alforja, Amanda Rey Torrente; Subthreshold diode micropulse laser photocoagulation versus low-fluence photodynamic therapy for the treatment of chronic central serous chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4140. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To compare clinical outcomes in patients with chronic central serous chorioretinopathy (cCSC), undergoing photocoagulation with subthreshold diode micropulse laser (SDM) versus low-fluence photodynamic therapy (PDT).
Retrospective, comparative, interventional case series. Thirty six eyes of 36 patients with no spontaneous resolution of neuroepithelial serous detachment confirmed by optical coherence tomography (OCT) and fluorescein angiography, after 6 months of the disease onset were included in this study, and underwent SDM or PDT. Best-corrected visual acuity (BCVA) and OCT were assessed prior to treatment and during the clinic follow-up.
We evaluated 20 eyes in the SDM group and 16 eyes in the PDT group. All patients had an anatomical and functional improvement after treatment, except for two patients in the PDT group. In the SDM group, the average improvement of BCVA was 0.39±0.22 with central foveal thickness decrease of 210.1±77.6 μm. The retreatment rate was 0.45. The clinical follow-up was 13.5±6 months. In the PDT group, the average improvement of BCVA was 0.20±0.30 with central foveal thickness decrease of 102 ± 761μm. The retreatment rate was 0.19. The clinical follow-up was 20.4 ± 14.2 months.
These preliminary results show that SDM is more effective, inexpensive and save than low fluence PDT in the treatment of cCSC.
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