June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
POSTURAL INTRAOCULAR PRESSURE CHANGES IN TRABECULECTOMIZED AND MEDICALLY-TREATED GLAUCOMA EYES
Author Affiliations & Notes
  • Akira Sawada
    Ophthalmology, Gifu Univ Grad School of Med, Gifu-shi, Japan
  • Tetsuya Yamamoto
    Ophthalmology, Gifu Univ Grad School of Med, Gifu-shi, Japan
  • Footnotes
    Commercial Relationships Akira Sawada, None; Tetsuya Yamamoto, Alcon Japan (R), Pfizer Japan (R), Senju (R), Santen (R), Kowa (R), Otsuka (R), Pfizer Japan (C), Senju (C), Kowa (C), Otsuka (C)
  • Footnotes
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Investigative Ophthalmology & Visual Science June 2013, Vol.54, 442. doi:https://doi.org/
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      Akira Sawada, Tetsuya Yamamoto; POSTURAL INTRAOCULAR PRESSURE CHANGES IN TRABECULECTOMIZED AND MEDICALLY-TREATED GLAUCOMA EYES. Invest. Ophthalmol. Vis. Sci. 2013;54(15):442. doi: https://doi.org/.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To compare the posture-induced intraocular pressure (IOP) changes in medically-treated and trabeculectomized glaucoma eyes with low IOPs

Methods: Thirty-five post-operated open-angle glaucoma (OAG) eyes with a cystic filtering bleb and 35 medically-treated OAG patients, which of both had IOPs with the Goldmann applanation tonometer (GAT) less than 12 mmHg, were enrolled into the study. The IOP was measured in the sitting and the lateral decubitus position with an ICare rebound tonometer (ICare). The IOP in the lateral decubitus position was measured in the upper-eyes 5 minutes after assuming this posture.

Results: The mean IOP measured with the GAT was 9.9 ± 1.4 mmHg in the trabeculectomized eyes and 10.0 ± 1.2 mmHg in the medically-treated eyes (P=0.646). In the surgically-treated group, the IOP with the ICare was 10.7 ± 2.5 mmHg in the sitting position and 11.9 ± 3.1 mmHg in the lateral decubitus position (P=0.000). On the other hand, in the medically-treated group, the IOP with the ICare was 11.4 ± 2.3 mmHg in the sitting position and 15.0 ± 2.7 mmHg in the lateral decubitus position (P=0.000). There was a significant difference in this postural IOP difference between the two groups, +1.2 mmHg in the surgically-treated group and +3.6 mmHg in the medically-treated group (P=0.000).

Conclusions: Our results indicate that successfully trabeculectomized eyes had less posture-induced IOP changes compared to medically-treated eyes.

Keywords: 568 intraocular pressure • 466 clinical (human) or epidemiologic studies: treatment/prevention assessment/controlled clinical trials • 765 wound healing  
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