June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Clinical and Tomographic Findings in Filtering Blebs Undergoing Digital Compression
Author Affiliations & Notes
  • Miriam Ramos-Hernandez
    Instituto de Oftalmologia y Ciencias Visuales, Guadalajara, Mexico
  • Miriam Ramos-Hernandez
    Instituto de Oftalmologia y Ciencias Visuales, Guadalajara, Mexico
  • Elia Chavez
    Instituto de Oftalmologia y Ciencias Visuales, Guadalajara, Mexico
  • Luz Giorgi-Sandoval
    Asistencia e Investigacion en Glaucoma, A.C., Guadalajara, Mexico
  • Jose Paczka
    Asistencia e Investigacion en Glaucoma, A.C., Guadalajara, Mexico
    Instituto de Oftalmologia y Ciencias Visuales, Guadalajara, Mexico
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 4494. doi:
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      Miriam Ramos-Hernandez, Miriam Ramos-Hernandez, Elia Chavez, Luz Giorgi-Sandoval, Jose Paczka; Clinical and Tomographic Findings in Filtering Blebs Undergoing Digital Compression. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4494.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To investigate clinical and tomographic profile of filtering blebs of eyes requiring digital compression to decrease intraocular pressure (IOP) as compared to blebs spontaneously achieving adequate IOP

 
Methods
 

We prospectively assessed 13 eyes which underwent primary mitomycin C augmented trabeculectomy and required continuous digital compression (DC) to achieve target IOP; 18 additional operated eyes (equivalent type of filtering surgery) not requiring digital compression (NRDC) to reach adequate level of IOP were also included in the study. All cases underwent clinical photography and anterior segment tomography (Cirrus anterior segment module of optical coherence tomography; Carl Zeiss Meditec; San Leandro, California, U.S.A.). Filtering bleb photographs and tomographic images were assessed by the same investigator (JAP) in a masked fashion. Würzburg filtering bleb score was used for clinical assessment. A novel weighted score for tomographic analysis was also applied.

 
Results
 

Thirteen eyes from 9 patients (mean age: 64.5 ± 8.2 years) belonging to the DC group had a mean IOP (13.4 ± 5.1 mm Hg) that was not significantly different to the mean value of IOP (14.1 ± 4.7 mm Hg, P > 0.05) of 18 eyes from 15 patients (mean age: 69.8 ± 4.9 years) of NRDC group. Mean scores derived from the Würzburg classification were not different between groups (8.5 ± 2.7. vs. 9.1 ± 3.2; DC vs. NRDC, respectively). In contrast, the tomographic score of the DC group (4.0 ± 2.6) was significantly different to the one obtained after scoring the NRDC group (7.6 ± 1.6, P = 0.01).

 
Conclusions
 

The current study suggests that structural findings of filtering blebs derived from anterior segment OCT (tomographic score) seems to perform better than clinical assessment to differentiate among blebs of different capacities of filtration.

 
Keywords: 568 intraocular pressure • 462 clinical (human) or epidemiologic studies: outcomes/complications • 550 imaging/image analysis: clinical  
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