June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Visual outcomes of the surgical treatment of idiopathic intracranial hypertension
Author Affiliations & Notes
  • Prem Subramanian
    Wilmer Eye Institute, Baltimore, MD
    Neurosurgery, Johns Hopkins Unversity Sch of Med, Baltimore, MD
  • Pedro Fonseca
    Wilmer Eye Institute, Baltimore, MD
  • Neil Miller
    Wilmer Eye Institute, Baltimore, MD
    Neurosurgery, Johns Hopkins Unversity Sch of Med, Baltimore, MD
  • Daniele Rigamonti
    Neurosurgery, Johns Hopkins Unversity Sch of Med, Baltimore, MD
  • Footnotes
    Commercial Relationships Prem Subramanian, None; Pedro Fonseca, None; Neil Miller, Quark Pharmaceutical Company (C); Daniele Rigamonti, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 4573. doi:
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      Prem Subramanian, Pedro Fonseca, Neil Miller, Daniele Rigamonti; Visual outcomes of the surgical treatment of idiopathic intracranial hypertension. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4573.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To evaluate the visual outcomes of optic nerve sheath fenestration (ONSF) and shunting procedures in patients with idiopathic intracranial hypertension (IIH).

 
Methods
 

Retrospective observational case series in which the medical records of patients with severe idiopathic intracranial hypertension who underwent surgical treatment at the Johns Hopkins Hospital were reviewed for demographics and clinical findings. Patients who underwent ONSF were compared to shunted patients.

 
Results
 

Thirty-eight patients (35 women and 3 men) with a mean age of 30.3 years (range, 9-52) underwent surgical treatment of IIH (16 ONSF, 22 shunt). Pre-operative Frisen scale papilledema in the ONSF group was grade 3 (14.3%), grade 4 (71.4%) and grade 5 (14.3%). In the shunt group 27.8% of patients had pre-operative optic atrophy, grade 1 (16.7%), grade 2 (33.3%), grade 3 (16.7%) and grade 4 (5.5%). Pre-operative visual acuity (VA) was 60.6 ETDRS letters in the ONSF group and 73.9 letters in the shunt group (p=0.13). There was a trend towards worse pre-operative mean deviation in the ONSF group (-22.94 dB vs -14.86 db, p=0.09). At the last follow-up mean VA was 75.3 letters in the ONSF group and 77.0 letters in the shunt group (p=0.56). Mean deviation was worse after ONSF (-17.36 dB vs -8.78 dB, p<0.05).

 
Conclusions
 

Both ONSF and shunting are effective procedures in stabilizing or improving visual acuity and visual fields in IIH patients. In general there was a trend towards worse visual pre-operative visual function that could explain the worse visual fields outcomes after ONSF.

 
Keywords: 627 optic disc • 759 visual impairment: neuro-ophthalmological disease  
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