June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Parameters related to Choroidal thickness
Author Affiliations & Notes
  • Yasuki Ito
    Ophthalmology, Nagoya University Graduate School of Medicine,, Nagoya, Japan
  • Kazuhiro Oiwa
    Ophthalmology, Nagoya University Graduate School of Medicine,, Nagoya, Japan
  • Eiji Iwata
    Ophthalmology, Nagoya University Graduate School of Medicine,, Nagoya, Japan
  • Akiko Takahashi
    Ophthalmology, Nagoya University Graduate School of Medicine,, Nagoya, Japan
  • Tetsuhiro Yasuma
    Ophthalmology, Nagoya University Graduate School of Medicine,, Nagoya, Japan
  • Kenichi Kawano
    Ophthalmology, Nagoya University Graduate School of Medicine,, Nagoya, Japan
  • Nobuyuki Hamajima
    Department of Preventive Medicine, Nagoya University Graduate School of Medicine,, Nagoya, Japan
  • Hiroko Terasaki
    Ophthalmology, Nagoya University Graduate School of Medicine,, Nagoya, Japan
  • Footnotes
    Commercial Relationships Yasuki Ito, None; Kazuhiro Oiwa, None; Eiji Iwata, None; Akiko Takahashi, None; Tetsuhiro Yasuma, None; Kenichi Kawano, None; Nobuyuki Hamajima, None; Hiroko Terasaki, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 4632. doi:
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      Yasuki Ito, Kazuhiro Oiwa, Eiji Iwata, Akiko Takahashi, Tetsuhiro Yasuma, Kenichi Kawano, Nobuyuki Hamajima, Hiroko Terasaki; Parameters related to Choroidal thickness. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4632.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: The choroidal thickness has been reported to be significantly correlated with age and axial length. In addition, the choroid in eyes with central serous chorioretinopathy (CSC) has been reported to be thicker. Because smoking is a risk factor of CSC, we tested the hypothesis that the choroid will be thicker in smokers. We also examined whether the choroidal thickness was affected by body weight.

Methods: A total of 495 subjects (197 men, 298 women) who were ≥40-years-of-age and were in the Comprehensive Health Examination Program (Yakumo Study) in 2011 were studied. All were examined by optical coherence tomography, fundus photography, and axial length measurements. The choroidal thickness was measured in the OCT images, and the relationship with the ocular parameters, bodyweight, sex, and smoking were determined.

Results: The average choroidal thickness was 222.3 ± 90.7 µm. The choroidal thickness was significantly correlated with age (P <0.0001), axial length (P <0.0001), and body weight (P <0.05). The choroidal thickness was thicker in smokers than in non-smokers (258.0 ± 110.2 µm vs 217.5 ± 87.1 µm, respectively; P <0.05). Regression analysis also showed that the choroidal thickness was significantly correlated negatively with age (P <0.0001), negatively with axial length (P <0.0001), positively with body weight (P <0.001) and with smoking (P <0.05). Sex was not significantly associated with choroidal thickness (P >0.05).

Conclusions: The choroidal thickness is associated with not only axial length and age, but also bodyweight and smoking. Smoking may disturb choroidal circulation and cause the thickening of choroid and may eventually increase the risk of CSC. In addition, body weight should also be considered to evaluate the choroidal thickness.

Keywords: 452 choroid • 688 retina  
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