June 2013
Volume 54, Issue 15
Free
ARVO Annual Meeting Abstract  |   June 2013
Persistent hypotony associated to the use of immunosuppressive therapy in glaucoma drainage implants
Author Affiliations & Notes
  • Susana Duch
    Ophthalmology- Glaucoma, Institut Condal d'Oftalmologia, Barcelona, Spain
  • Oana Stirbu
    Ophthalmology- Glaucoma, Institut Condal d'Oftalmologia, Barcelona, Spain
  • Elena Milla
    Ophthalmology- Glaucoma, Institut Condal d'Oftalmologia, Barcelona, Spain
  • Oscar Buchacra Castellano
    Ophthalmology- Glaucoma, Institut Condal d'Oftalmologia, Barcelona, Spain
  • Footnotes
    Commercial Relationships Susana Duch, None; Oana Stirbu, None; Elena Milla, None; Oscar Buchacra Castellano, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2013, Vol.54, 4791. doi:https://doi.org/
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Susana Duch, Oana Stirbu, Elena Milla, Oscar Buchacra Castellano; Persistent hypotony associated to the use of immunosuppressive therapy in glaucoma drainage implants. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4791. doi: https://doi.org/.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: To describe the histopathology of non-valved implants in three cases of persistent postoperative Hypotony after the restrictive tube ligature was released, in patients under long term immunosuppressive therapy.

Methods: Human tissue study of surgical pathology specimens with clinicopathological correlation

Results: The macroscopic appearance of the capsules, 3 and 4 months postoperatively, was immature and loose. Microscopic examination disclosed extremely irregular and loose tissue, its thickness measuring from 0.02 to 0.6mm, depending on the place of the capsule that was studied. The withdrawal of the immunosuppressive therapy did not allow the rebuilding of new capsules, and implant exchange with a valved device was needed, in order to recover IOP.

Conclusions: The use of chronic immunosuppressants may interfere with the capsule formation around the plates in non-valved drainage devices.Thus, in theses cases valved implants might be safer.

Keywords: 765 wound healing • 568 intraocular pressure • 638 pathology: human  
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×