Purchase this article with an account.
SAAD AL-DAHMASH, Carol Shields, Swathi Kaliki, Timothy Johnson, Jerry Shields; Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Metastasis in 31 Eyes. Invest. Ophthalmol. Vis. Sci. 2013;54(15):4865.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To describe the characteristics of choroidal metastasis using enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT).
A retrospective observational study.
Of 31eyes with choroidal metastasis imaged with EDI-OCT, 14 (45%) displayed image detail suitable for study. The metastasis originated from breast carcinoma (n=7, 50 %), lung carcinoma (n=5, 36%), pancreatic carcinoma (n=1, 7%), and thyroid carcinoma (n=1, 7%). The mean tumor basal diameter was 6.4 mm and thickness 2.3 mm by B-scan ultrasonography. The tumor was located in the macula in 6 (43 %) and was extramacular in 8 (57%) cases. By EDI-OCT, the mean tumor thickness was 987 μm. The tumor features included irregular (“lumpy bumpy”) anterior contour (n=9, 64%), posterior shadowing (n=12, 86%), and anterior compression of the overlying choriocapillaris (n=13, 93%), with retinal pigment epithelium (RPE) abnormalities (n=11, 78%). Outer retinal features included structural loss of photoreceptors (n=9, 64%), inner segment-outer segment (IS-OS) junction (n=8, 57%), external limiting membrane (n=4, 29%), outer nuclear layer (n=1, 7%), and outer plexiform layer (n=1, 7%). Inner retinal layers from the inner nuclear layer and inwards was normal. Subretinal fluid (n=11, 79%), subretinal lipofuscin (n=1, 7%), and intraretinal edema (n=2, 14%) were identified.
EDI-OCT features of choroidal metastasis include irregular (lumpy bumpy) anterior tumor surface, and disruption of RPE and outer retinal layers with preservation of the inner retinal layers.
This PDF is available to Subscribers Only