Abstract
Purpose:
Several kinds of spectral domain optical coherence tomography (SD-OCT) compatible with measurement of subfoveal choroidal thickness (SFCT) have become commercially available. However there is little research about the differences between various models. In this study, the purpose is to compare SFCT measured using 3D OCT-2000 (Topcon, Corp., Tokyo, Japan) and SPECTRALIS HLA+OCT (Heidelberg Engineering, Heidelberg, Germany).
Methods:
Forty four eyes of 37 patients without any structural abnormality in the retinal images of the OCT were examined using both SD-OCTs. SFCT measured with 3D OCT-2000 was viewed as grayscale images for the first half (twenty two eyes of 17 patients) and as color images for the second half (twenty two eyes of 20 patients). The SFCT measured with SPECTRALIS HLA+OCT was viewed as grayscale images for both groups.
Results:
The SFCTs (mean+/-SD, µm) measured with SPECTRALIS HLA+OCT were 251.5+/-69.1 and 278.0+/-88.7, and the SFCTs measured with 3D OCT-2000 were 245.2+/-69.7 and 277.6+/-88.1, in the first and second groups respectively. With each instrument, there was no significant difference between the groups (P=0.209, P=0.115, Mann-Whitney U-test). In the first group, the SFCTs measured with 3D OCT-2000 were significantly thinner than those measured with SPECTRALIS HLA+OCT (P=0.034, Wilcoxon t-test). In the second group, the SFCTs showed no difference between those two OCTs.
Conclusions:
The SFCT measurement using grayscale image with 3D OCT-2000 might appear thinner than the SFCT measured with SPECTRALIS HLA+OCT.
Keywords: 550 imaging/image analysis: clinical •
552 imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) •
452 choroid